Mortality in schizophrenia: 30‐year nationwide follow‐up study

A. Tanskanen; J. Tiihonen; H. Taipale

doi:10.1111/acps.12913

journal article Jun 13, 2018

Mortality in schizophrenia: 30‐year nationwide follow‐up study

A. Tanskanen J. Tiihonen H. Taipale

Acta Psychiatrica Scandinavica Vol. 138 No. 6 pp. 492-499 · Wiley

View at Publisher Save 10.1111/acps.12913

Abstract

ObjectiveRecent reports suggest that the mortality gap between persons with schizophrenia and the general population is increasing. We investigated the mortality, age at death, and causes of death among persons diagnosed with schizophrenia and the general population in Finland during 1984–2014.MethodsAll persons with schizophrenia in Finland were identified from hospital discharge register, and compared with the Finnish population aged 16 years and older during 1984–2014, based on data from Statistics Finland. Age at death and standardized mortality ratio (SMR) were calculated for each follow‐up year.ResultsMean age at death increased from 57.6 years in 1984 to 70.1 years in 2014 in persons with schizophrenia, and from 70.9 to 77.5 years in the general population. All‐cause SMR remained stable during the follow‐up (2.6 in 1984 and 2.7 in 2014). A major change was observed in SMR for suicides which decreased from 11.0 in 1984 to 6.6 in 2014 (−40%). The SMRs for cardiovascular and cancer deaths showed increasing trends.ConclusionThe longevity of persons with schizophrenia is improving at approximately the same rate as the general population but suicide rates have declined substantially. However, there is still a major disparity in mortality compared with general population.

Topics

No keywords indexed for this article. Browse by subject →

References

25

[1]

10.1016/j.schres.2017.09.005

[2]

10.1192/bjp.bp.117.202606

[3]

10.1016/s2215-0366(17)30078-0

[4]

10.1056/nejmms1610125

[5]

10.1093/schbul/sbu138

[6]

10.1503/cmaj.161351

[7]

10.1016/j.schres.2013.02.025

[8]

10.1111/acps.12742

[9]

10.1016/s0140-6736(09)60742-x

[10]

A Nationwide Cohort Study of Oral and Depot Antipsychotics After First Hospitalization for Schizophrenia

Jari Tiihonen, Jari Haukka, Mark Taylor et al.

American Journal of Psychiatry 10.1176/appi.ajp.2011.10081224

[11]

10.1001/jamapsychiatry.2017.1322

[12]

10.1093/schbul/sbx176

[13]

10.1177/1359786810385490

[14]

10.7326/0003-4819-140-10-200405180-00037

[15]

10.1007/s12199-013-0329-7

[16]

10.1192/bjp.bp.117.198952

[17]

10.1017/s0033291712000396

[18]

Mortality Rates After the First Diagnosis of Psychotic Disorder in Adolescents and Young Adults

Gregory E. Simon, Christine Stewart, Bobbi Jo Yarborough et al.

JAMA Psychiatry 10.1001/jamapsychiatry.2017.4437

[19]

Statistics Finland's PX‐Web databases [Internet]. Available from:http://pxnet2.stat.fi/PXWeb/pxweb/en/StatFin/StatFin__vrm__synt/statfin_synt_pxt_001.px/?rxid=6e4b2c6d-c45c-4810-95f2-141986ba549f

[20]

10.1177/0269881107075509

[21]

10.1016/j.schres.2005.02.010

[22]

10.1017/s0033291708004194

[23]

10.1097/yco.0b013e32835035ca

[24]

10.1192/bjp.173.6.494

[25]

10.1007/s00127-010-0209-z

Cited By

129

A Case for Thalamic Mechanisms of Schizophrenia: Perspective From Modeling 22q11.2 Deletion Syndrome

Yanbo Jiang, Mary H. Patton · 2021

Frontiers in Neural Circuits

High Intensity Interval training (HIIT) for people with severe mental illness: A systematic review & meta-analysis of intervention studies– considering diverse approaches for mental and physical recovery

Nicole Korman, Michael Armour · 2020

Psychiatry Research

The American Psychiatric Association Practice Guideline for the Treatment of Patients With Schizophrenia

George A. Keepers, Laura J. Fochtmann · 2020

American Journal of Psychiatry

The Lancet Psychiatry Commission: a blueprint for protecting physical health in people with mental illness

Joseph Firth, Najma Siddiqi · 2019

The Lancet Psychiatry

Evidence-based guidelines for the pharmacological treatment of schizophrenia: Updated recommendations from the British Association for Psychopharmacology

Thomas RE Barnes, Richard Drake · 2019

Journal of Psychopharmacology

Effects of chronic physical illness on treatment outcomes among patients with schizophrenia

Ivona Šimunović Filipčić, Žarko Bajić · 2019

Current Opinion in Psychiatry

Metrics

129

Citations

25

References

Details

Published: Jun 13, 2018
Vol/Issue: 138(6)
Pages: 492-499
License: View

Authors

A

A. Tanskanen

Department of Clinical Neuroscience Karolinska Institutet Stockholm Sweden; Department of Forensic Psychiatry Niuvanniemi Hospital University of Eastern Finland Kuopio Finland

J

J. Tiihonen

Department of Clinical Neuroscience Karolinska Institutet Stockholm Sweden; Department of Forensic Psychiatry Niuvanniemi Hospital University of Eastern Finland Kuopio Finland; Center for Psychiatry Research Stockholm City Council Stockholm Sweden

H

H. Taipale

Department of Clinical Neuroscience Karolinska Institutet Stockholm Sweden; Department of Forensic Psychiatry Niuvanniemi Hospital University of Eastern Finland Kuopio Finland; School of Pharmacy University of Eastern Finland Kuopio Finland

Funding

Niuvanniemi Hospital

Cite This Article

A. Tanskanen, J. Tiihonen, H. Taipale (2018). Mortality in schizophrenia: 30‐year nationwide follow‐up study. Acta Psychiatrica Scandinavica, 138(6), 492-499. https://doi.org/10.1111/acps.12913

Mortality in schizophrenia: 30‐year nationwide follow‐up study

You May Also Like