Nicotinicα4β2acetylcholine receptors and cognitive function in Parkinson's disease

R. Lorenz; S. Samnick; U. Dillmann; M. Schiller; M. F. Ong; K. Faßbender; A. Buck; J. Spiegel

doi:10.1111/ane.12259

journal article Apr 25, 2014

Nicotinicα4β2acetylcholine receptors and cognitive function in Parkinson's disease

R. Lorenz S. Samnick U. Dillmann M. Schiller

M. F. Ong K. Faßbender A. Buck J. Spiegel

Acta Neurologica Scandinavica Vol. 130 No. 3 pp. 164-171 · Hindawi Limited

View at Publisher Save 10.1111/ane.12259

Topics

No keywords indexed for this article. Browse by subject →

References

28

[1]

Deuschl (1999)

[2]

Braak "Stages in the development of Parkinson's disease-related pathology" Cell Tissue Res (2004) 10.1007/s00441-004-0956-9

[3]

Borghammer "Perfusion and metabolism imaging studies in Parkinson's disease" Dan Med J (2012)

[4]

Fujita "Quantification of nicotinergic acetylcholine receptors in human brain using [123I]5-I-A-85380 SPET" Eur J Nucl Med Mol Imaging (2003) 10.1007/s00259-003-1320-0

[5]

Mamede "Quantification of human nicotinic acetylcholine receptors with 123I-5IA-SPECT" J Nucl Med (2004)

[6]

Staley "123I-5-IA-85380 SPECT measurement of nicotinic acetylcholine receptors in human brain by the constant infusion paradigm: feasibility and reproducibility" J Nucl Med (2005)

[7]

Fujita "Widespread decrease of nicotinic acetylcholine receptors in Parkinson's disease" Ann Neurol (2006) 10.1002/ana.20688

[8]

Kas "Decrease of nicotinic receptors in the nigrostriatal system in Parkinson's disease" J Cereb Blood Flow Metab (2009) 10.1038/jcbfm.2009.74

[9]

Oishi "Quantification of nicotinic acetylcholine receptors in Parkinson's disease with (123)I-5IA SPECT" J Neurol Sci (2007) 10.1016/j.jns.2007.02.014

[10]

Mukhin "5-iodo-A-85380, an α4β2 subtype-ligand for nicotinic acetylcholine receptors" Mol Pharmacol (2000) 10.1124/mol.57.3.642

[11]

Pimlott "Nicotinic acetylcholine receptor distribution in Alzheimer′s disease, dementia with Lewy bodies, Parkinson's disease and vascular dementia: In vitro binding study using 5-[125I]-A-85380" Neuropsychopharmacology (2004) 10.1038/sj.npp.1300302

[12]

Schmaljohann "In vitro evaluation of nicotinic acetylcholine receptors with 2-[18F]F-A85380 in Parkinson's disease" Nucl Med Biol (2006) 10.1016/j.nucmedbio.2005.12.012

[13]

Meyer "Reduced alpha4beta2-nicotinic acetylcholine receptor binding and its relationship to mild cognitive and depressive symptoms in Parkinson disease" Arch Gen Psychiatry (2009) 10.1001/archgenpsychiatry.2009.106

[14]

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assesment of Alzheimer's disease

J. C. Moms, A. Heyman, R. C. Mohs et al.

Neurology 1989 10.1212/wnl.39.9.1159

[15]

Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases.

A J Hughes, S E Daniel, L Kilford et al.

Journal of Neurology, Neurosurgery &amp; Psych... 1992 10.1136/jnnp.55.3.181

[16]

Miah "Early-stage cognitive impairment in Parkinson's disease and the influence of dopamine replacement therapy" Eur J Neurol (2012) 10.1111/j.1468-1331.2011.03578.x

[17]

Molloy "Effect of levodopa on cognitive function in Parkinson's disease with and without dementia and dementia with Lewy bodies" J Neurol Neurosurg Psychiatry (2006) 10.1136/jnnp.2006.098079

[18]

Morrison "Effects of levodopa on cognitive functioning in moderate-to-severe Parkinson's disease (MSPD)" J Neural Transm (2004) 10.1007/s00702-004-0145-8

[19]

Chang "A method for attenuation correction in radionuclide computed tomography" IEEE Trans Nucl Sci (1978) 10.1109/tns.1978.4329385

[20]

Berres "Normal ranges of neuropsychological tests for the diagnosis of Alzheimer's disease" Stud Health Technol Inform (2000)

[21]

Bohnen "The cholinergic system and Parkinson's disease" Behav Brain Res (2011) 10.1016/j.bbr.2009.12.048

[22]

Atack "Molecular forms of acetylcholinesterase and butyrylcholinesterase in the aged human central nervous system" J Neurochem (1986) 10.1111/j.1471-4159.1986.tb02858.x

[23]

Bohnen "Heterogeneity of cholinergic denervation in Parkinson's disease without dementia" J Cereb Blood Flow Metab (2012) 10.1038/jcbfm.2012.60

[24]

Kotagal "Thalamic cholinergic innervation is spared in Alzheimer disease compared to parkinsonian disorders" Neurosci Lett (2012) 10.1016/j.neulet.2012.02.083

[25]

Müller "Cholinergic dysfunction in Parkinson's disease" Curr Neurol Neurosci Rep (2013) 10.1007/s11910-013-0377-9

[26]

Bohnen "Gait speed in Parkinson's disease correlates with cholinergic degeneration" Neurology (2013) 10.1212/wnl.0b013e3182a9f558

[27]

Benarroch "Pedunculopontine nucleus: functional organization and clinical implications" Neurology (2013) 10.1212/wnl.0b013e3182886a76

[28]

Mesulam "Cholinergic circuitry of the human nucleus basalis and its fate in Alzheimer′s disease" J Comp Neurol (2013) 10.1002/cne.23415

Cited By

27

Cortical α4β2-nicotinic acetylcholine receptors and cognitive decline in Parkinson's disease

Kelly A Mills, Hiroto Kuwabara · 2025

Journal of Parkinson’s Disease

PET Imaging of Cholinergic Neurotransmission in Neurodegenerative Disorders

Solveig Tiepolt, Philipp M. Meyer · 2022

Journal of Nuclear Medicine

Nicotinic Acetylcholine Receptor Density in Cognitively Intact Subjects at an Early Stage of Parkinsonâ€™s Disease

Ioannis Ugo Isaias, JÃ¶rg Spiegel · 2014

Frontiers in Aging Neuroscience

Metrics

27

Citations

28

References

Details

Published: Apr 25, 2014
Vol/Issue: 130(3)
Pages: 164-171
License: View

Authors

R

R. Lorenz

Department of Nuclear Medicine; University of Würzburg; Würzburg Germany

S

S. Samnick

Department of Nuclear Medicine; University of Würzburg; Würzburg Germany

U

U. Dillmann

Department of Neurology; Saarland University; Homburg/Saar Germany

M

M. Schiller

Department of Nuclear Medicine; University of Würzburg; Würzburg Germany

M

M. F. Ong

Department of Biometry; Epidemiology and Medical Informatics; Saarland University; Homburg/Saar Germany

K

K. Faßbender

Department of Neurology; Saarland University; Homburg/Saar Germany

A

A. Buck

Department of Nuclear Medicine; University of Würzburg; Würzburg Germany

J

J. Spiegel

Department of Neurology; Saarland University; Homburg/Saar Germany

Cite This Article

R. Lorenz, S. Samnick, U. Dillmann, et al. (2014). Nicotinicα4β2acetylcholine receptors and cognitive function in Parkinson's disease. Acta Neurologica Scandinavica, 130(3), 164-171. https://doi.org/10.1111/ane.12259

Nicotinicα4β2acetylcholine receptors and cognitive function in Parkinson's disease

You May Also Like