Nitric oxide signalling in the brain and its control of bodily functions

Konstantina Chachlaki; Vincent Prevot

doi:10.1111/bph.14800

journal article Sep 08, 2019

Nitric oxide signalling in the brain and its control of bodily functions

Konstantina Chachlaki

Vincent Prevot

British Journal of Pharmacology Vol. 177 No. 24 pp. 5437-5458 · Wiley

View at Publisher Save 10.1111/bph.14800

Abstract

Nitric oxide (NO) is a versatile molecule that plays key roles in the development and survival of mammalian species by endowing brain neuronal networks with the ability to make continual adjustments to function in response to moment‐to‐moment changes in physiological input. Here, we summarize the progress in the field and argue that NO‐synthetizing neurons and NO signalling in the brain provide a core hub for integrating sensory‐ and homeostatic‐related cues, control key bodily functions, and provide a potential target for new therapeutic opportunities against several neuroendocrine and behavioural abnormalities.

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References

Details

Published: Sep 08, 2019
Vol/Issue: 177(24)
Pages: 5437-5458
License: View

Authors

K

Konstantina Chachlaki

Inserm, Laboratory of Development and Plasticity of the Neuroendocrine Brain Jean‐Pierre Aubert Research Centre, UMR‐S 1172 Lille France; School of Medicine University of Lille Lille France; CHU Lille FHU 1,000 days for Health Lille France

V

Vincent Prevot

Inserm, Laboratory of Development and Plasticity of the Neuroendocrine Brain Jean‐Pierre Aubert Research Centre, UMR‐S 1172 Lille France; School of Medicine University of Lille Lille France; CHU Lille FHU 1,000 days for Health Lille France

Funding

Agence Nationale de la Recherche Award: ANR‐17‐CE16‐0015‐01

European Genomic Institute for Diabetes

Cite This Article

Konstantina Chachlaki, Vincent Prevot (2019). Nitric oxide signalling in the brain and its control of bodily functions. British Journal of Pharmacology, 177(24), 5437-5458. https://doi.org/10.1111/bph.14800

Nitric oxide signalling in the brain and its control of bodily functions

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