journal article Open Access Oct 30, 2025

Using miniaturized laboratory equipment and DNA barcoding to improve conservation genetics training and identify illegally traded species

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Abstract
Abstract
Illegal wildlife trade (IWT) is one of the largest global illegal activities, and it negatively affects biodiversity and sustainable development worldwide. DNA barcoding coupled with high‐throughput sequencing (i.e., metabarcoding) is useful in identifying taxa affected by IWT and has been used routinely for decades. However, for countries lacking laboratory infrastructure, sequencing units, and trained staff, the application of DNA barcoding tools in conservation is limited and depends on slow sample transport processes and molecular analyses carried out abroad. Guinea‐Bissau, on the West African coast, has one of the lowest human development indices in the world and is a biodiversity hotspot threatened by IWT. We explored the potential use of inexpensive and portable miniaturized laboratory equipment (MLE) and DNA barcoding tools to improve training in conservation genetics and identification of traded species. We tested these technologies in tissue samples collected at different times and contexts in Guinea‐Bissau and used 3 primer pairs amplifying mitochondrial DNA fragments. We successfully identified 33 tissue samples to the species level; thus, MLE may accelerate the use of DNA and metabarcoding methods in countries that have low research funding and limited infrastructure. The use of these technologies has the potential to advance the discipline of conservation genetics in Guinea‐Bissau and other countries and to train students and employees of government agencies dedicated to investigating environmental crimes.
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References
69
[1]
GenBank

D. A. Benson, Mark Cavanaugh, Karen Clark et al.

Nucleic Acids Research 10.1093/nar/gks1195
[4]
TreeViewer: Flexible, modular software to visualise and manipulate phylogenetic trees

Giorgio Bianchini, Patricia Sánchez‐Baracaldo

Ecology and Evolution 10.1002/ece3.10873
[5]
Next-generation technologies applied to age-old challenges in Madagascar

Marina B. Blanco, Lydia K. Greene, Fidisoa Rasambainarivo et al.

Conservation Genetics 10.1007/s10592-020-01296-0
[6]
BLAST: a more efficient report with usability improvements

Grzegorz M. Boratyn, Christiam Camacho, Peter S. Cooper et al.

Nucleic Acids Research 10.1093/nar/gkt282
[7]
Brugiére D. "Distribution and status of lions and leopards in southern Guinea‐Bissau and western Guinea, West Africa" Cat News (2005)
[9]
Cá A.(2008).Estudos sobre caça e mercado de primatas em Tombali Sul da Guiné‐Bissau(PhD dissertation).Instituto de Ciências Biológicas Universidade Federal de Minas Gerais.
[10]
Casanova C. &Sousa C.(2007).Plano de acção nacional para a conservação das populações de chimpanzés cólubus vermelhos ocidentais e cólubus brancos e pretos ocidentais na República da Guiné‐Bissau.Instituto da Biodiversidade e das Áreas Protegidas (IBAP).
[11]
Central Intelligence Agency (CIA). (2024).Guinea‐Bissau factbook.https://www.cia.gov/the‐world‐factbook/countries/guinea‐bissau/
[19]
Ferreira da Silva M. J. "A qualitative assessment of Guinea‐Bissau's hunting history and culture and their implications for primate conservation" African Primates (2021)
[23]
Biological identifications through DNA barcodes

Paul D. N. Hebert, Alina Cywinska, Shelley L. Ball et al.

Proceedings of the Royal Society of London. Series... 10.1098/rspb.2002.2218
[24]
Limited resources of genome sequencing in developing countries: Challenges and solutions

Mohamed Helmy, Mohamed Awad, Kareem A. Mosa

Applied & Translational Genomics 10.1016/j.atg.2016.03.003
[27]
Multiple Alignment of DNA Sequences with MAFFT

Kazutaka Katoh, George Asimenos, Hiroyuki Toh

Methods in Molecular Biology™ 10.1007/978-1-59745-251-9_3
[31]
Cutadapt removes adapter sequences from high-throughput sequencing reads

Marcel Martin

EMBnet.journal 10.14806/ej.17.1.200
[38]
Nellemann C. (2016)
[39]
Nellemann C. (2014)
[40]
IQ-TREE: A Fast and Effective Stochastic Algorithm for Estimating Maximum-Likelihood Phylogenies

Lam-Tung Nguyen, Heiko A. Schmidt, Arndt von Haeseler et al.

Molecular Biology and Evolution 10.1093/molbev/msu300
[47]
Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples

Joshua Quick, Nathan D Grubaugh, Steven T Pullan et al.

Nature Protocols 10.1038/nprot.2017.066
[49]
Summarizing the Evidence on the International Trade in Illegal Wildlife

Gail Emilia Rosen, Katherine F. Smith

EcoHealth 10.1007/s10393-010-0317-y
[50]
Rowe N. (2016)

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Details
Published
Oct 30, 2025
Vol/Issue
40(2)
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Authors
Funding
European Regional Development Fund Award: NORTE‐01‐0145‐FEDER‐000046
Fundação para a Ciência e a Tecnologia Award: UID/00713/2020
Mohamed bin Zayed Species Conservation Fund Award: 232533027
Cite This Article
Maria Joana Ferreira da Silva, Ivo Colmonero‐Costeira, Saidil Lamine Djaló, et al. (2025). Using miniaturized laboratory equipment and DNA barcoding to improve conservation genetics training and identify illegally traded species. Conservation Biology, 40(2). https://doi.org/10.1111/cobi.70165
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