Integrated circuits and molecular components for stress and feeding: implications for eating disorders

J. A. Hardaway; N. A. Crowley; C. M. Bulik; T. L. Kash

doi:10.1111/gbb.12185

journal article Jan 01, 2015

Integrated circuits and molecular components for stress and feeding: implications for eating disorders

J. A. Hardaway N. A. Crowley C. M. Bulik T. L. Kash

Genes, Brain and Behavior Vol. 14 No. 1 pp. 85-97 · Wiley

View at Publisher Save 10.1111/gbb.12185

Abstract

Eating disorders are complex brain disorders that afflict millions of individuals worldwide. The etiology of these diseases is not fully understood, but a growing body of literature suggests that stress and anxiety may play a critical role in their development. As our understanding of the genetic and environmental factors that contribute to disease in clinical populations like anorexia nervosa, bulimia nervosa and binge eating disorder continue to grow, neuroscientists are using animal models to understand the neurobiology of stress and feeding. We hypothesize that eating disorder clinical phenotypes may result from stress‐induced maladaptive alterations in neural circuits that regulate feeding, and that these circuits can be neurochemically isolated using animal model of eating disorders.

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Metrics

58

Citations

179

References

Details

Published: Jan 01, 2015
Vol/Issue: 14(1)
Pages: 85-97
License: View

Authors

J

J. A. Hardaway

Bowles Alcohol Center University of North Carolina at Chapel Hill NC USA

N

N. A. Crowley

Bowles Alcohol Center University of North Carolina at Chapel Hill NC USA

C

C. M. Bulik

UNC Eating Disorders Program University of North Carolina at Chapel Hill NC USA

T

T. L. Kash

Bowles Alcohol Center University of North Carolina at Chapel Hill NC USA

Funding

National Institutes of Health Award: AA011605

Cite This Article

J. A. Hardaway, N. A. Crowley, C. M. Bulik, et al. (2015). Integrated circuits and molecular components for stress and feeding: implications for eating disorders. Genes, Brain and Behavior, 14(1), 85-97. https://doi.org/10.1111/gbb.12185

Integrated circuits and molecular components for stress and feeding: implications for eating disorders

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