Abstract
AbstractBackgroundToxoplasmosis is a zoonotic disease that affects humans and warm‐blooded animals. This study describes an outbreak of toxoplasmosis in howler monkeys (Alouatta sp.) and survival of capuchins (Sapajus apella), under the same environmental conditions.MethodsHowler monkeys were submitted to post‐mortem examination. Tissue samples were processed to histopathology and immunohistochemistry to detect lesions and tachyzoites of Toxoplasma gondii. Tissue samples were also frozen and submitted to PCR and genotyping of T. gondii.ResultsTypical lesions were observed in several organs including the liver, lymph node, and brain, with intralesional cysts and tachyzoites of T. gondii demonstrated by immunohistochemistry. T. gondii genomic sequences were amplified by PCR, and genotyping characterized the same T. gondii clone in all howler monkeys.ConclusionsOur results support the notion that some species of neotropical primates are highly susceptible to toxoplasmosis and the hypothesis that capuchins (S. apella) may be resistant.
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18
Citations
32
References
Details
Published
Dec 06, 2020
Vol/Issue
50(2)
Pages
99-107
License
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Authors
Funding
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Conselho Nacional de Desenvolvimento Cientifico e Tecnologico
Fundação de Amparo à Pesquisa do Estado de Minas Gerais
Cite This Article
Clarissa Helena Santana, Ayisa Rodrigues de Oliveira, Daniel O. dos Santos, et al. (2020). Genotyping of Toxoplasma gondii in a lethal toxoplasmosis outbreak affecting captive howler monkeys (Alouatta sp.). Journal of Medical Primatology, 50(2), 99-107. https://doi.org/10.1111/jmp.12506