Duchenne muscular dystrophy

Eppie M Yiu; Andrew J Kornberg

doi:10.1111/jpc.12868

journal article Mar 09, 2015

Duchenne muscular dystrophy

Eppie M Yiu Andrew J Kornberg

Journal of Paediatrics and Child Health Vol. 51 No. 8 pp. 759-764 · Wiley

View at Publisher Save 10.1111/jpc.12868

Abstract

AbstractDuchenne muscular dystrophy, an X‐linked disorder, has an incidence of one in 5000 boys and presents in early childhood with proximal muscle weakness. Untreated boys become wheelchair bound by the age of 12 years and die of cardiorespiratory complications in their late teens to early 20s. The use of corticosteroids, non‐invasive respiratory support, and active surveillance and management of associated complications have improved ambulation, function, quality of life and life expectancy. The clinical features, investigations and management of Duchenne muscular dystrophy are reviewed, as well as the latest in some of the novel therapies.

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Metrics

263

Citations

48

References

Details

Published: Mar 09, 2015
Vol/Issue: 51(8)
Pages: 759-764
License: View

Authors

E

Eppie M Yiu

Neurology Department Royal Children's Hospital Melbourne Melbourne Victoria Australia; Bruce Lefroy Centre Murdoch Childrens Research Institute Melbourne Victoria Australia; Neurosciences Research Murdoch Childrens Research Institute Melbourne Victoria Australia; Department of Paediatrics The University of Melbourne Melbourne Victoria Australia

A

Andrew J Kornberg

Neurology Department Royal Children's Hospital Melbourne Melbourne Victoria Australia; Neurosciences Research Murdoch Childrens Research Institute Melbourne Victoria Australia; Department of Paediatrics The University of Melbourne Melbourne Victoria Australia

Funding

Victorian Government's Operational Infrastructure Support Program

National Health Medical Research Council of Australia (NHMRC) Early Career Fellowship

Cite This Article

Eppie M Yiu, Andrew J Kornberg (2015). Duchenne muscular dystrophy. Journal of Paediatrics and Child Health, 51(8), 759-764. https://doi.org/10.1111/jpc.12868

Duchenne muscular dystrophy

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