Seizure-precipitating factors in dogs with idiopathic epilepsy

Johanna A. Forsgård; Liisa Metsähonkala; Anna-Mariam Kiviranta; Sigitas Cizinauskas; Jouni J.T. Junnila; Outi Laitinen-Vapaavuori; Tarja S. Jokinen

doi:10.1111/jvim.15402

journal article Open Access Mar 01, 2019

Seizure-precipitating factors in dogs with idiopathic epilepsy

Johanna A. Forsgård

Liisa Metsähonkala Anna-Mariam Kiviranta

Sigitas Cizinauskas Jouni J.T. Junnila Outi Laitinen-Vapaavuori Tarja S. Jokinen

Journal of Veterinary Internal Medicine Vol. 33 No. 2 pp. 701-707 · Oxford University Press (OUP)

View at Publisher Save 10.1111/jvim.15402

Abstract

Abstract

Background
Stress, sleep deprivation, and infectious diseases are important seizure-precipitating factors in human epilepsy patients. However, these factors have not been thoroughly studied in epileptic dogs.

Objective
Seizure-precipitating factors are common in dogs with idiopathic epilepsy and the occurrence of these factors associate with the dogs' signalment, personality, and epilepsy-related factors.

Animals
Fifty dogs with diagnosed idiopathic epilepsy from the hospital populations of University Veterinary Teaching Hospital of University of Helsinki and Referral Animal Hospital Aisti.

Methods
In a retrospective cross-sectional observational study, owners were interviewed about their dogs' possible seizure-precipitating factors according to a predefined questionnaire. The dogs were identified and selected by searching the medical records of the participating animal hospitals.

Results
The prevalence of seizure-precipitating factors in the study population was 74% (37/50). The most frequently reported factors included stress-related situations, sleep deprivation, weather, and hormonal factors. In dogs with focal onset seizures, the number of precipitating factors was 1.9 (95% CI 1.1-3.4) times higher compared to dogs with generalized seizures.

Conclusions and Clinical Importance
Seizure-precipitating factors are common in dogs with idiopathic epilepsy, and the nature of these factors is consistent with those of human patients. Aside from antiepileptic medication, acknowledging and avoiding seizure-precipitating factors could help veterinarians achieve better treatment outcomes.

Topics

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Citations

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References

Details

Published: Mar 01, 2019
Vol/Issue: 33(2)
Pages: 701-707
License: View

Authors

J

Johanna A. Forsgård

Faculty of Veterinary Medicine, University of Helsinki Department of Equine and Small Animal Medicine, , Helsinki,

L

Liisa Metsähonkala

Pediatric Neurologist, Hospital of Children and Adolescents, Helsinki University Central Hospital , Helsinki,

A

Anna-Mariam Kiviranta

Faculty of Veterinary Medicine, University of Helsinki Department of Equine and Small Animal Medicine, , Helsinki,

S

Sigitas Cizinauskas

Referral Animal Hospital Aisti , Vantaa,

J

Jouni J.T. Junnila

4Pharma Ltd , Helsinki,

O

Outi Laitinen-Vapaavuori

Faculty of Veterinary Medicine, University of Helsinki Department of Equine and Small Animal Medicine, , Helsinki,

T

Tarja S. Jokinen

Faculty of Veterinary Medicine, University of Helsinki Department of Equine and Small Animal Medicine, , Helsinki,

Cite This Article

Johanna A. Forsgård, Liisa Metsähonkala, Anna-Mariam Kiviranta, et al. (2019). Seizure-precipitating factors in dogs with idiopathic epilepsy. Journal of Veterinary Internal Medicine, 33(2), 701-707. https://doi.org/10.1111/jvim.15402

Seizure-precipitating factors in dogs with idiopathic epilepsy

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