Natural history of hypertrophic cardiomyopathy in cats from rehoming centers: The CatScan II study

Jose Novo Matos; Jessie Rose Payne; Joonbum Seo; Virginia Luis Fuentes

doi:10.1111/jvim.16576

journal article Open Access Nov 01, 2022

Natural history of hypertrophic cardiomyopathy in cats from rehoming centers: The CatScan II study

Jose Novo Matos

Jessie Rose Payne Joonbum Seo

Virginia Luis Fuentes

Journal of Veterinary Internal Medicine Vol. 36 No. 6 pp. 1900-1912 · Oxford University Press (OUP)

View at Publisher Save 10.1111/jvim.16576

Abstract

Abstract

Background
The natural history of hypertrophic cardiomyopathy (HCM) in cats has been mainly studied in cats referred for suspected heart disease, which can skew the results towards cats with clinical signs. Few data are available on factors associated with development of HCM in cats.

Hypotheses
(1) Clinical variables can predict which cats will develop HCM; (2) HCM in cats not referred for suspected heart disease is associated with a low rate of cardiovascular events.

Animals
One hundred seven cats from rehoming centers without a history of clinical signs of cardiac or systemic disease at the time of adoption.

Methods
Prospective longitudinal study. After rehoming, shelter cats were reexamined for serial echocardiograms. Cox regression analysis was used to identify predictors of development of HCM in cats that were normal at baseline. Adverse cardiovascular events including heart failure, thromboembolism, or sudden death were recorded.

Results
Cats were monitored for a median of 5.6 [1.2-9.2] years. At baseline, 68/107 cats were normal, 18/107 were equivocal and 21/107 had HCM. Nineteen cats developed HCM during the study period. The factors at baseline associated with increased hazard of developing HCM were lower left atrial fractional shortening, higher left ventricular fractional shortening, and higher body weight. Cardiovascular events were observed in 21% of cats with HCM.

Conclusions and Clinical Importance
Cardiovascular events were common in cats with HCM from a rehoming center study sample. Lower left atrial systolic function appears to precede overt HCM.

Topics

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Details

Published: Nov 01, 2022
Vol/Issue: 36(6)
Pages: 1900-1912
License: View

Authors

J

Jose Novo Matos

Clinical Science and Services, Royal Veterinary College , Hertfordshire,

J

Jessie Rose Payne

Langford Vets Small Animal Referral Hospital, University of Bristol , Bristol,

J

Joonbum Seo

Animal Referral Centre , Auckland,; School of Veterinary Science, Massey University , Palmerston North,

V

Virginia Luis Fuentes

Clinical Science and Services, Royal Veterinary College , Hertfordshire,

Funding

Petplan Charitable Trust

Everts Luff Feline Endowment

Cite This Article

Jose Novo Matos, Jessie Rose Payne, Joonbum Seo, et al. (2022). Natural history of hypertrophic cardiomyopathy in cats from rehoming centers: The CatScan II study. Journal of Veterinary Internal Medicine, 36(6), 1900-1912. https://doi.org/10.1111/jvim.16576

Natural history of hypertrophic cardiomyopathy in cats from rehoming centers: The CatScan II study

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