Wound closure and alveoplasty after preventive tooth extractions in patients with antiresorptive intake—A randomized pilot trial

Oliver Ristow; Thomas Rückschloß; Julius Moratin; Michael Müller; Reinald Kühle; Horn Dominik; Maximilian Pilz; Veronika Shavlokhova; Sven Otto; Jürgen Hoffmann; Christian Freudlsperger

doi:10.1111/odi.13556

journal article Open Access Aug 10, 2020

Wound closure and alveoplasty after preventive tooth extractions in patients with antiresorptive intake—A randomized pilot trial

Oliver Ristow

Thomas Rückschloß

Julius Moratin

Michael Müller

Reinald Kühle Horn Dominik Maximilian Pilz

Veronika Shavlokhova Sven Otto

Jürgen Hoffmann

Christian Freudlsperger

Oral Diseases Vol. 27 No. 3 pp. 532-546 · Wiley

View at Publisher Save 10.1111/odi.13556

Abstract

AbstractObjectivesTo compare success rates between the sub‐periosteal prepared (SPP) muco‐periosteal flap and the epi‐periosteal prepared (EPP) mucosa flap and the feasibility of alveoplasty after surgical tooth extractions in patients undergoing/after antiresorptive treatment.SubjectsPatients with an indication for preventive tooth extraction undergoing/after antiresorptive treatment were enrolled over a 24‐month period in a parallel‐group randomized clinical pilot trial and randomly assigned for primary wound closure to either the SPP or the EPP group. The primary outcome was treatment failure 8 weeks after surgery. To assess the feasibility of alveoplasty, necrotic bone changes at the time point of tooth extraction were evaluated.ResultsOne hundred and sixty patients were randomized to the SSP (n = 82) or the EPP (n = 78) group. One hundred and fifty‐seven patients met the primary endpoint 8 weeks after surgery with five treatment failures for the SPP group (6.3%) and 18 (23.4%) for the EPP group (p = .004). A significant relationship (p < .0001) was observed between symptomatic teeth and non‐vital bone found in 54.8% of all biopsies.ConclusionsThe strong superiority of the muco‐periosteal flap as primary wound closure revealed the feasibility and effectiveness of the study. The large number of necrotic biopsies emphasizes the importance of alveoplasty as a preventive measure.

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Metrics

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Citations

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References

Details

Published: Aug 10, 2020
Vol/Issue: 27(3)
Pages: 532-546
License: View

Authors

O

Oliver Ristow

Department of Oral and Maxillofacial Surgery University of Heidelberg Heidelberg Germany

T

Thomas Rückschloß

Department of Oral and Maxillofacial Surgery University of Heidelberg Heidelberg Germany

J

Julius Moratin

Department of Oral and Maxillofacial Surgery University of Heidelberg Heidelberg Germany

M

Michael Müller

Department of Oral and Maxillofacial Surgery University of Heidelberg Heidelberg Germany

R

Reinald Kühle

Department of Oral and Maxillofacial Surgery University of Heidelberg Heidelberg Germany

H

Horn Dominik

Department of Oral and Maxillofacial Surgery Saarland University Homburg Germany

M

Maximilian Pilz

Department of Biometry Institute of Medical Biometry and Informatics University of Heidelberg Heidelberg Germany

V

Veronika Shavlokhova

Department of Oral and Maxillofacial Surgery University of Heidelberg Heidelberg Germany

S

Sven Otto

Department of Oral and Maxillofacial Surgery Martin‐Luther‐University Halle‐Wittenberg Halle (Saale) Germany

J

Jürgen Hoffmann

Department of Oral and Maxillofacial Surgery University of Heidelberg Heidelberg Germany

C

Christian Freudlsperger

Department of Oral and Maxillofacial Surgery University of Heidelberg Heidelberg Germany

Funding

Deutsche Forschungsgemeinschaft Award: RI2813/2‐1

Cite This Article

Oliver Ristow, Thomas Rückschloß, Julius Moratin, et al. (2020). Wound closure and alveoplasty after preventive tooth extractions in patients with antiresorptive intake—A randomized pilot trial. Oral Diseases, 27(3), 532-546. https://doi.org/10.1111/odi.13556

Wound closure and alveoplasty after preventive tooth extractions in patients with antiresorptive intake—A randomized pilot trial

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