Metabolic Syndrome Increases the Prevalence of Spine Osteoarthritis

Rajiv Gandhi; Kenneth M Woo; Michael G Zywiel; Y Raja Rampersaud

doi:10.1111/os.12093

journal article Feb 01, 2014

Metabolic Syndrome Increases the Prevalence of Spine Osteoarthritis

Rajiv Gandhi Kenneth M Woo Michael G Zywiel Y Raja Rampersaud

Orthopaedic Surgery Vol. 6 No. 1 pp. 23-27 · Wiley

View at Publisher Save 10.1111/os.12093

Abstract

ObjectiveTo determine whether the prevalence of severe spinal osteoarthritis (OA) increases with the number of metabolic syndrome (MetS) risk factors.MethodsData from a single surgeon's high volume, spine surgery practice were reviewed. Severe OA was defined as degenerative spondylolisthesis or cervical or lumbar stenosis causing neurologically based symptoms and early OA as lumbar and cervical spondylosis causing axial pain only. Logistic regression modeling was used to determine the odds (adjusted for age and sex) of having severe spine OA with more numerous MetS risk factors.ResultsSevere spinal OA was identified in 839/1502 patients (55.9%) and early OA in the remaining 663 individuals (44.1%). The overall prevalence of MetS was 30/1502 (2.0%): 26/839 (3.1%) in the severe OA group and 4/663 (0.6%) in the early OA group (P = 0.001). Presence of all four MetS risk factors was associated with almost quadruple the odds of having severe OA as compared with absence of risk factors (OR 3.9 [1.4–11.6], P < 0.01).ConclusionThe components of MetS are more prevalent in subjects with severe spinal OA than in those with spondylosis causing axial pain. Future study of the association between MetS and the incidence of OA is required.

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Details

Published: Feb 01, 2014
Vol/Issue: 6(1)
Pages: 23-27
License: View

Authors

R

Rajiv Gandhi

Division of Orthopaedic Surgery Toronto Western Hospital University of Toronto Toronto Ontario Canada

K

Kenneth M Woo

Division of Orthopaedic Surgery Toronto Western Hospital University of Toronto Toronto Ontario Canada

M

Michael G Zywiel

Division of Orthopaedic Surgery Toronto Western Hospital University of Toronto Toronto Ontario Canada

Y

Y Raja Rampersaud

Division of Orthopaedic Surgery Toronto Western Hospital University of Toronto Toronto Ontario Canada

Cite This Article

Rajiv Gandhi, Kenneth M Woo, Michael G Zywiel, et al. (2014). Metabolic Syndrome Increases the Prevalence of Spine Osteoarthritis. Orthopaedic Surgery, 6(1), 23-27. https://doi.org/10.1111/os.12093

Metabolic Syndrome Increases the Prevalence of Spine Osteoarthritis

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