ISPAD Clinical Practice Consensus Guidelines 2018: Glycemic control targets and glucose monitoring for children, adolescents, and young adults with diabetes

Diabetes Control and Complications Trial Research Group "The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus" N Engl J Med (1993) 10.1056/nejm199309303291401

[2]

Diabetes Control and Complications Trial Research Group "Effect of intensive diabetes treatment on the development and progression of long-term complications in adolescents with insulin-dependent diabetes mellitus: diabetes control and complications trial" J Pediatr (1994) 10.1016/s0022-3476(94)70190-3

[3]

Lachin "Effect of glycemic exposure on the risk of microvascular complications in the diabetes control and complications trial--revisited" Diabetes (2008) 10.2337/db07-1618

[4]

Nathan "Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration: the diabetes control and complications trial/epidemiology of diabetes interventions and complications and Pittsburgh epidemiology of diabetes complications experience (1983-2005)" Arch Intern Med (2009) 10.1001/archinternmed.2009.193

[5]

White "Beneficial effects of intensive therapy of diabetes during adolescence: outcomes after the conclusion of the Diabetes Control and Complications Trial (DCCT)" J Pediatr (2001) 10.1067/mpd.2001.118887

[6]

Hofer "Tracking of metabolic control from childhood to young adulthood in type 1 diabetes" J Pediatr (2014) 10.1016/j.jpeds.2014.07.001

[7]

Samuelsson "A high mean-HbA1c value 3-15 months after diagnosis of type 1 diabetes in childhood is related to metabolic control, macroalbuminuria, and retinopathy in early adulthood--a pilot study using two nation-wide population based quality registries" Pediatr Diabetes (2014) 10.1111/pedi.12085

[8]

Donaghue "The effect of prepubertal diabetes duration on diabetes. Microvascular complications in early and late adolescence" Diabetes Care (1997) 10.2337/diacare.20.1.77

[9]

Genuth "Effects of prior intensive versus conventional therapy and history of glycemia on cardiac function in type 1 diabetes in the DCCT/EDIC" Diabetes (2013) 10.2337/db12-0546

[10]

Writing Team for the DCCT/EDIC Research Group "Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy: the epidemiology of diabetes interventions and complications (EDIC) study" JAMA (2003) 10.1001/jama.290.16.2159

[11]

Gubitosi-Klug "Effects of prior intensive insulin therapy and risk factors on patient-reported visual function outcomes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) cohort" JAMA Ophthalmol (2016) 10.1001/jamaophthalmol.2015.4606

[12]

Orchard "Association between 7 years of intensive treatment of type 1 diabetes and long-term mortality" JAMA (2015) 10.1001/jama.2014.16107

[13]

Arbelaez "Glycemic extremes in youth with T1DM: the structural and functional integrity of the developing brain" Pediatr Diabetes (2013) 10.1111/pedi.12088

[14]

Barnea-Goraly "Alterations in white matter structure in young children with type 1 diabetes" Diabetes Care (2014) 10.2337/dc13-1388

[15]

Broadley "A systematic review and meta-analysis of executive function performance in type 1 diabetes mellitus" Psychosom Med (2017) 10.1097/psy.0000000000000460

[16]

Perantie "Regional brain volume differences associated with hyperglycemia and severe hypoglycemia in youth with type 1 diabetes" Diabetes Care (2007) 10.2337/dc07-0351

[17]

Ryan "Neurocognitive consequences of diabetes" Am Psychol (2016) 10.1037/a0040455

[18]

Foland-Ross "Longitudinal assessment of hippocampus structure in children with type 1 diabetes" Pediatr Diabetes (2018) 10.1111/pedi.12683

[19]

Aye "White matter structural differences in young children with type 1 diabetes: a diffusion tensor imaging study" Diabetes Care (2012) 10.2337/dc12-0017

[20]

Ryan "Why is cognitive dysfunction associated with the development of diabetes early in life? The diathesis hypothesis" Pediatr Diabetes (2006) 10.1111/j.1399-5448.2006.00206.x

[21]

Cooper "A population-based study of risk factors for severe hypoglycaemia in a contemporary cohort of childhood-onset type 1 diabetes" Diabetologia (2013) 10.1007/s00125-013-2982-1

[22]

Downie "Continued reduction in the prevalence of retinopathy in adolescents with type 1 diabetes: role of insulin therapy and glycemic control" Diabetes Care (2011) 10.2337/dc11-0102

[23]

Johnson "Long-term outcome of insulin pump therapy in children with type 1 diabetes assessed in a large population-based case-control study" Diabetologia (2013) 10.1007/s00125-013-3007-9

[24]

Ly "Effect of sensor-augmented pump therapy and automated insulin suspension vs standard insulin pump therapy on hypoglycemia in patients with type 1 diabetes: a randomized clinical trial" JAMA (2013) 10.1001/jama.2013.277818

[25]

Bohn "20 years of pediatric benchmarking in Germany and Austria: age-dependent analysis of longitudinal follow-up in 63,967 children and adolescents with type 1 diabetes" PLoS One (2016) 10.1371/journal.pone.0160971

[26]

Haynes "Severe hypoglycemia rates are not associated with HbA1c: a cross-sectional analysis of 3 contemporary pediatric diabetes registry databases" Pediatr Diabetes (2017) 10.1111/pedi.12477

[27]

Karges "for the DPV Initiative Glycated hemoglobin A1c as a risk factor for severe hypoglycemia in pediatric type 1 diabetes" Pediatr Diabetes (2017) 10.1111/pedi.12348

[28]

Karges "Hemoglobin A1c levels and risk of severe hypoglycemia in children and young adults with type 1 diabetes from Germany and Austria: a trend analysis in a cohort of 37,539 patients between 1995 and 2012" PLoS Med (2014) 10.1371/journal.pmed.1001742

[29]

Davis "Acute hyperglycaemia impairs cognitive function in children with IDDM" J Pediatr Endocrinol Metab (1996) 10.1515/jpem.1996.9.4.455

[30]

Martin "Acute effects of hyperglycemia in children with type 1 diabetes mellitus: the patient's perspective" J Pediatr Endocrinol Metab (2006) 10.1515/jpem.2006.19.7.927

[31]

Nathan "Translating the A1C assay into estimated average glucose values" Diabetes Care (2008) 10.2337/dc08-0545

[32]

Bergenstal "for the T1D Exchange Racial Differences Study Group. Racial differences in the relationship of glucose concentrations and hemoglobin A1c levels" Ann Intern Med (2017) 10.7326/m16-2596

[33]

Beck "The fallacy of average: how using HbA1c alone to assess glycemic control can be misleading" Diabetes Care (2017) 10.2337/dc17-0636

[34]

Herman "Do race and ethnicity impact hemoglobin A1c independent of glycemia?" J Diabetes Sci Technol (2009) 10.1177/193229680900300406

[35]

Venkataraman "Ethnicity modifies the relation between fasting plasma glucose and HbA1c in Indians, Malays and Chinese" Diabet Med (2012) 10.1111/j.1464-5491.2012.03599.x

[36]

Wilson "Hemoglobin A1c and mean glucose in patients with type 1 diabetes: analysis of data from the Juvenile Diabetes Research Foundation continuous glucose monitoring randomized trial" Diabetes Care (2011) 10.2337/dc10-1054

[37]

Wilson "for the Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Study Group Persistence of individual variations in glycated hemoglobin: analysis of data from the Juvenile Diabetes Research Foundation continuous glucose monitoring randomized trial" Diabetes Care (2011) 10.2337/dc10-1661

[38]

Hempe "High and low hemoglobin glycation phenotypes in type 1 diabetes: a challenge for interpretation of glycemic control" J Diabetes Complicat (2002) 10.1016/s1056-8727(01)00227-6

[39]

Haller "Predictors of control of diabetes: monitoring may be the key" J Pediatr (2004) 10.1016/j.jpeds.2003.12.042

[40]

Miller "for the T1D Exchange Clinic Network. Evidence of a strong association between frequency of self-monitoring of blood glucose and hemoglobin A1c levels in T1D Exchange clinic registry participants" Diabetes Care (2013) 10.2337/dc12-1770

[41]

Redondo "for the Pediatric Diabetes Consortium. Pediatric diabetes consortium type 1 diabetes new onset (NeOn) study: factors associated with HbA1c levels one year after diagnosis" Pediatr Diabetes (2014) 10.1111/pedi.12061

[42]

Ziegler "for the DPV-Wiss-Initiative Frequency of SMBG correlates with HbA1c and acute complications in children and adolescents with type 1 diabetes" Pediatr Diabetes (2011) 10.1111/j.1399-5448.2010.00650.x

[43]

Tsalikian "Prevention of hypoglycemia during exercise in children with type 1 diabetes by suspending basal insulin" Diabetes Care (2006) 10.2337/dc06-0495

[44]

Bergenstal "Identifying variables associated with inaccurate self-monitoring of blood glucose: proposed guidelines to improve accuracy" Diabetes Educ (2000) 10.1177/014572170002600610

[45]

Schmid "System accuracy of blood glucose monitoring systems: impact of use by patients and ambient conditions" Diabetes Technol Ther (2013) 10.1089/dia.2013.0047

[46]

https://www.fda.gov/downloads/ucm380327.pdf

[47]

Roberts "Exercise in youth with type 1 diabetes" Curr Pediatr Rev (2015) 10.2174/1573396311666150702105340

[48]

Chiang "Type 1 diabetes through the life span: a position statement of the American Diabetes Association" Diabetes Care (2014) 10.2337/dc14-1140

[49]

Beckles "Diagnosis and management of diabetes in children and young people: summary of updated NICE guidance" BMJ (2016) 10.1136/bmj.i139

[50]

American Diabetes Association "12. Children and Adolescents: Standards of Medical Care in Diabetes-2018" Diabetes Care (2018) 10.2337/dc18-s012

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Details

Published: Oct 01, 2018
Vol/Issue: 19
Pages: 105-114
License: View

Authors

L

Linda A. DiMeglio

Division of Pediatric Endocrinology and Diabetology and Wells Center for Pediatric Research, Department of Pediatrics; Indiana University School of Medicine; Indianapolis Indiana

C

Carlo L. Acerini

Department of Paediatrics; University of Cambridge; Cambridge UK

E

Ethel Codner

Institute of Maternal and Child Research (IDMI), School of Medicine; Universidad de Chile; Santiago Chile

M

Maria E. Craig

Institute of Endocrinology and Diabetes, Children's Hospital at Westmead; Sydney Australia

S

Sabine E. Hofer

Department of Pediatrics; Medical University of Innsbruck; Innsbruck Austria

K

Kubendran Pillay

Westville Hospital; Durban South Africa

D

David M. Maahs

Division of Pediatric Endocrinology; Stanford University; Stanford California

Cite This Article

Linda A. DiMeglio, Carlo L. Acerini, Ethel Codner, et al. (2018). ISPAD Clinical Practice Consensus Guidelines 2018: Glycemic control targets and glucose monitoring for children, adolescents, and young adults with diabetes. Pediatric Diabetes, 19, 105-114. https://doi.org/10.1111/pedi.12737

ISPAD Clinical Practice Consensus Guidelines 2018: Glycemic control targets and glucose monitoring for children, adolescents, and young adults with diabetes

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