Synthesis and Potentiometric Titrations of Some New 4-(Benzylideneamino)-4,5-dihydro-1H-1,2,4-triazol-5-one Derivatives in Non-Aqueous Media

Şule Bahçeci; Haydar Yüksek; Zafer Ocak; Ibrahim Azakli; Muzaffer Alkan; Mustafa Ozdemir

doi:10.1135/cccc20021215

journal article Jan 01, 2002

Synthesis and Potentiometric Titrations of Some New 4-(Benzylideneamino)-4,5-dihydro-1H-1,2,4-triazol-5-one Derivatives in Non-Aqueous Media

Şule Bahçeci Haydar Yüksek

Zafer Ocak Ibrahim Azakli Muzaffer Alkan Mustafa Ozdemir

Collection of Czechoslovak Chemical Communications Vol. 67 No. 8 pp. 1215-1222 · Institute of Organic Chemistry & Biochemistry

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Abstract

The synthesis of 3-alkyl(aryl)-4-[4-(dimethylamino)benzylideneamino]-4,5-dihydro-1H-1,2,4-triazol-5-ones (3) from the reactions of 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (2) with 4-(dimethylamino)benzaldehyde is described. The newly synthesized 3 type compounds were titrated potentiometrically with tetrabutylammonium hydroxide in three non-aqueous solvents, including acetonitrile, isopropyl alcohol and N,N-dimethylformamide. The half-neutralization potential values and the corresponding pKa values were determined for all cases. Thus, the effects of solvents and molecular structure upon acidity were investigated. In addition, N-acetyl derivatives of 3 type compounds were also obtained. The new synthesized compounds in the study were fully characterized.

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Details

Published: Jan 01, 2002
Vol/Issue: 67(8)
Pages: 1215-1222

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Cite This Article

Şule Bahçeci, Haydar Yüksek, Zafer Ocak, et al. (2002). Synthesis and Potentiometric Titrations of Some New 4-(Benzylideneamino)-4,5-dihydro-1H-1,2,4-triazol-5-one Derivatives in Non-Aqueous Media. Collection of Czechoslovak Chemical Communications, 67(8), 1215-1222. https://doi.org/10.1135/cccc20021215

Synthesis and Potentiometric Titrations of Some New 4-(Benzylideneamino)-4,5-dihydro-1H-1,2,4-triazol-5-one Derivatives in Non-Aqueous Media

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