Solvent-free syntheses of some quinazolin-4(3H)-ones derivatives

S Mohana Roopan; T Maiyalagan; F Nawaz Khan

doi:10.1139/v08-149

journal article Nov 01, 2008

Solvent-free syntheses of some quinazolin-4(3H)-ones derivatives

S Mohana Roopan T Maiyalagan F Nawaz Khan

Canadian Journal of Chemistry Vol. 86 No. 11 pp. 1019-1025 · Canadian Science Publishing

View at Publisher Save 10.1139/v08-149

Abstract

Solvent-free syntheses of quinazolin-4(3H)-ones were performed by reaction of anthranillic acid with different amides, such as nicotinamide, benzamide, formamide, etc., on montmorillonite K-10. Products were confirmed by FTIR, 1HNMR, and 13CNMR spectroscopic techniques. All synthesized compounds exhibited antioxidant properties and have been compared with standard antioxidant BHT.Key words: quinazolinone, montmorillonite K-10, solvent-free conditions, antioxidant properties.

Topics

No keywords indexed for this article. Browse by subject →

References

32

[1]

D.J. Brown. In Comprehensive heterocyclic chemistry. Vol. 3. Edited by A.R. Katritzky and C.W Rees. Pergamon Press, Oxford, UK. 1984. p. 57.

[2]

Wamhoff J. Dzenis. Adv. Heterocyclic. Chem. (1992) 10.1016/s0065-2725(08)60222-6

[3]

Sinha M. Srivastava. Prog. Drug Res. (1994)

[4]

Gao X. Z. Chen. Molecules (2007) 10.3390/12122621

[5]

Yang Z. Xu. Bioorg. Med. Chem. Lett. (2007) 10.1016/j.bmcl.2007.01.101

[6]

Bartroli E. J. Forn. J.Med.Chem. (1998) 10.1021/jm9707277

[7]

B.A. Keay and P.W. Dibble. In Comprehensive Heterocyclic Chemistry. Vol. II. Edited by A.R. Katritzky, C.W. Rees, and E.F.V. Scriven. Pergamon Press, Oxford, UK. 1996. pp. 395-436. 10.1016/b978-008096518-5.00047-2

[8]

Kunes J. J. Janota. Il Farmaco (2000) 10.1016/s0014-827x(00)00100-2

[9]

Grover S.G. Kini. Eur. J. Med. Chem. (2006) 10.1016/j.ejmech.2005.09.002

[10]

Tiwari V.K. Mishra. Eur. J. Med. Chem. (2007) 10.1016/j.ejmech.2007.01.002

[11]

Synthesis of novel 4,6-disubstituted quinazoline derivatives, their anti-inflammatory and anti-cancer activity (cytotoxic) against U937 leukemia cell lines☆

P. Mani Chandrika, T. Yakaiah, A. Raghu Ram Rao et al.

European Journal of Medicinal Chemistry 2008 10.1016/j.ejmech.2007.06.010

[12]

Connolly D. J. Guiry. Tetrahedron (2005) 10.1016/j.tet.2005.07.010

[13]

Buckley N. Williams. Bioorg. Med. Chem. Lett. (2005) 10.1016/j.bmcl.2004.11.015

[14]

Rad-Moghadam M. Mohseni. J. Chem. Res. Synop.

[15]

Ried W. Stephan. Chem. Ber. (1963) 10.1002/cber.19630960507

[16]

Yang A. Kaplan. Tetrahedron Lett. (2000) 10.1016/s0040-4039(00)01201-6

[17]

Alagarsamy S. De Clercq. Indian J. Pharm. Sci. (2007) 10.4103/0250-474x.33167

[18]

Pannerselvam R.V. Sridhar. Indian J. Pharm. Sci. (2003)

[19]

Varma. Green Chem. (1999) 10.1039/a808223e

[20]

Varma. Clean Prod. Pros. (1999)

[21]

Nawaz Khan R. Chem. (2003)

[22]

Nawaz Khan R. Pillai. Tetrahedron Lett. (2002) 10.1016/s0040-4039(02)01496-x

[23]

Hathwar P. Guru Row. Acta Crystallogr. Sect. E (2007) 10.1107/s1600536807037671

[24]

Hathwar P. Guru Row. Acta Crystallogr. Sect. E (2007) 10.1107/s1600536807037683

[25]

Syed Tajudeen F. Nawaz Khan. Synth. Commun. (2007) 10.1080/00397910701557796

[26]

Bhor N.S. Bhanage. Ulrasonics Sonochemistry (2008) 10.1016/j.ultsonch.2007.03.008

[27]

Kidwai Mohan. J. Chin. Chem. Soc. (2006)

[28]

Ansari L. Pieroni. Phytother. Res. (2005) 10.1002/ptr.1756

[29]

Chen M. Xie. J. Agric. Food Chem. (2004)

[30]

Jaleel P. Biointerfaces (2007) 10.1016/j.colsurfb.2007.06.010

[31]

T.Mc.C. Paterson, R.K. Smalley, and H. Suschitzky. Synthesis, 187 (1975).

[32]

F. Li, Y. Feng, Q. Meng, W. Li, Z. Li, Q. Wang, and F. Tao. ARKIVOC, i, 40 (2007). 10.3998/ark.5550190.0008.105

Cited By

65

Palladium-Catalyzed Three-Component Coupling of 2-Iodoanilines, Isocyanides, and Carbon Dioxide

T. K. Nguyen, S. A. Katkova · 2025

Russian Journal of Organic Chemistr...

Recent advances in synthesis of quinazoline‐2,4(1H,3H)‐diones: Versatile building blocks in N‐heterocyclic compounds

Davood Gheidari, Morteza Mehrdad · 2022

Applied Organometallic Chemistry

Efficient Catalytic and Thermal Syntheses of Novel Thiadiazole, Triazole, Benzothiazole, and Fused Quinazoline Derivatives

M. H. M. Abd El-Azim, M. G. Assay · 2022

Russian Journal of Organic Chemistr...

Synthesis and Antimicrobial Assessments of Some Quinazolines and Their Annulated Systems

Magdy M. Hemdan, Ahmed S.A. Youssef · 2017

Journal of Chemical Research

Metrics

65

Citations

32

References

Details

Published: Nov 01, 2008
Vol/Issue: 86(11)
Pages: 1019-1025
License: View

Authors

Cite This Article

S Mohana Roopan, T Maiyalagan, F Nawaz Khan (2008). Solvent-free syntheses of some quinazolin-4(3H)-ones derivatives. Canadian Journal of Chemistry, 86(11), 1019-1025. https://doi.org/10.1139/v08-149

Solvent-free syntheses of some quinazolin-4(3H)-ones derivatives

You May Also Like