RIBOSOMES AND TRANSLATION

Rachel Green; Harry F. Noller

doi:10.1146/annurev.biochem.66.1.679

journal article Jun 01, 1997

RIBOSOMES AND TRANSLATION

Rachel Green

Harry F. Noller

Annual Review of Biochemistry Vol. 66 No. 1 pp. 679-716 · Annual Reviews

View at Publisher Save 10.1146/annurev.biochem.66.1.679

Abstract

The ribosome is a large multifunctional complex composed of both RNA and proteins. Biophysical methods are yielding low-resolution structures of the overall architecture of ribosomes, and high-resolution structures of individual proteins and segments of rRNA. Accumulating evidence suggests that the ribosomal RNAs play central roles in the critical ribosomal functions of tRNA selection and binding, translocation, and peptidyl transferase. Biochemical and genetic approaches have identified specific functional interactions involving conserved nucleotides in 16S and 23S rRNA. The results obtained by these quite different approaches have begun to converge and promise to yield an unprecedented view of the mechanism of translation in the coming years.

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References

202

[1]

Watson JD Bull. Soc. Chim. Biol. (1964)

[2]

Hill WE (1990)

[3]

Nierhaus KH (1992)

[4]

10.1139/o95-082

[5]

Zimmermann RA (1996)

[6]

Intermediate states in the movement of transfer RNA in the ribosome

Danesh Moazed, Harry F. Noller

Nature 10.1038/342142a0

[7]

Noller HF, Moazed D. 1993. InNucleic Acids and Molecular Biology, ed. F Eckstein, DMJ Lilley, 7:324–36. Heidelberg: Springer-Verlag 10.1007/978-3-642-77950-3_20

[8]

Hardesty B, Odom OW, Deng H-Y. 1986. InThe Structure, Function and Genetics of Ribosomes, ed. B Hardesty, G Kramer, pp. 495–508. New York: Springer–Verlag 10.1007/978-1-4612-4884-2_28

[9]

10.1021/bi00500a004

[10]

10.1002/j.1460-2075.1989.tb08574.x

[11]

10.1073/pnas.93.9.4202

[12]

10.1021/bi00473a001

[13]

10.1073/pnas.93.22.12183

[14]

10.1021/bi00359a025

[15]

The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution.

J. Czworkowski, J. Wang, T. A. Steitz et al.

The EMBO Journal 10.1002/j.1460-2075.1994.tb06675.x

[16]

10.1002/j.1460-2075.1994.tb06676.x

[17]

Crystal Structure of the Ternary Complex of Phe-tRNA Phe , EF-Tu, and a GTP Analog

Poul Nissen, Morten Kjeldgaard, Søren Thirup et al.

Science 10.1126/science.270.5241.1464

[18]

10.1016/0022-2836(90)90074-v

[19]

10.1016/0300-9084(94)90063-9

[20]

10.1126/science.8446899

[21]

10.1073/pnas.92.6.1945

[22]

10.1139/o95-112

[23]

10.1073/pnas.71.10.4135

[24]

10.1016/s0300-9084(75)80139-8

[25]

Thompson RC J. Biol. Chem. (1981) 10.1016/s0021-9258(19)69044-7

[26]

10.1074/jbc.271.2.646

[27]

10.1016/0168-9525(94)90016-7

[28]

10.1016/s0022-2836(05)80023-3

[29]

10.1126/science.274.5291.1367

[30]

10.1111/j.1432-1033.1994.tb20059.x

[31]

10.1002/j.1460-2075.1996.tb00453.x

[32]

10.1073/pnas.91.20.9223

[33]

10.1093/nar/22.16.3392

[34]

10.1074/jbc.270.16.9322

[35]

10.1126/science.271.5251.990

[36]

Characterization and preliminary attempts for derivatization of crystals of large ribosomal subunits from Haloarcula marismortui diffracting to 3 Å resolution

K. von Böhlen, I. Makowski, H.A.S. Hansen et al.

Journal of Molecular Biology 10.1016/0022-2836(91)90730-t

[37]

10.1139/o95-082

[38]

A new crystalline form of 30 S ribosomal subunits from Thermus thermophilus

M.M. Yusupov, S.V. Tischenko, S.D. Trakhanov et al.

FEBS Letters 10.1016/0014-5793(88)80237-0

[39]

10.1016/0300-9084(91)90130-s

[40]

10.1016/0968-0004(89)90166-7

[41]

10.1016/s0022-2836(05)80315-8

[42]

10.1016/0022-2836(89)90282-9

[43]

10.1016/0167-4781(90)90132-l

[44]

The structure of ribosomal protein S5 reveals sites of interaction with 16S rRNA

V. Ramakrishnan, Stephen W. White

Nature 10.1038/358768a0

[45]

Crystal structure of the ribosomal protein S6 from Thermus thermophilus.

M. Lindahl, L.A. Svensson, A. Liljas et al.

The EMBO Journal 10.1002/j.1460-2075.1994.tb06376.x

[46]

White SW. 1997. In press

[47]

Ribosomal protein S17: Characterization of the three-dimensional structure by proton and nitrogen-15 NMR

Barbara L. Golden, David W. Hoffman, V. Ramakrishnan et al.

Biochemistry 10.1021/bi00210a033

[48]

Crystal structure of the RNA binding ribosomal protein L1 from Thermus thermophilus.

S. Nikonov, N. Nevskaya, I. Eliseikina et al.

The EMBO Journal 10.1002/j.1460-2075.1996.tb00477.x

[49]

Crystal structure of a ribosomal component at 2.6 Å resolution

Marie Leijonmarck, Stig Eriksson, Anders Liljas

Nature 10.1038/286824a0

[50]

10.1002/j.1460-2075.1994.tb06250.x

Showing 50 of 202 references

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Metrics

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Citations

202

References

Details

Published: Jun 01, 1997
Vol/Issue: 66(1)
Pages: 679-716

Authors

R

Rachel Green

Center for Molecular Biology of RNA, Sinsheimer Laboratories, University of California, Santa Cruz, California 95064

H

Harry F. Noller

Center for Molecular Biology of RNA, Sinsheimer Laboratories, University of California, Santa Cruz, California 95064

Cite This Article

Rachel Green, Harry F. Noller (1997). RIBOSOMES AND TRANSLATION. Annual Review of Biochemistry, 66(1), 679-716. https://doi.org/10.1146/annurev.biochem.66.1.679

RIBOSOMES AND TRANSLATION

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