Human Embryonic Stem Cells: A Model for the Study of Neural Development and Neurological Diseases

Piya Prajumwongs; Oratai Weeranantanapan; Thiranut Jaroonwitchawan; Parinya Noisa

doi:10.1155/2016/2958210

journal article Open Access Jan 01, 2016

Human Embryonic Stem Cells: A Model for the Study of Neural Development and Neurological Diseases

Piya Prajumwongs Oratai Weeranantanapan Thiranut Jaroonwitchawan Parinya Noisa

Stem Cells International Vol. 2016 No. 1 · Hindawi Limited

View at Publisher Save 10.1155/2016/2958210

Abstract

Although the mechanism of neurogenesis has been well documented in other organisms, there might be fundamental differences between human and those species referring to species‐specific context. Based on principles learned from other systems, it is found that the signaling pathways required for neural induction and specification of human embryonic stem cells (hESCs) recapitulated those in the early embryo development in vivo at certain degree. This underscores the usefulness of hESCs in understanding early human neural development and reinforces the need to integrate the principles of developmental biology and hESC biology for an efficient neural differentiation.

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Details

Published: Jan 01, 2016
Vol/Issue: 2016(1)
License: View

Authors

P

Piya Prajumwongs

O

Oratai Weeranantanapan

T

Thiranut Jaroonwitchawan

P

Parinya Noisa

Funding

Suranaree University of Technology

Cite This Article

Piya Prajumwongs, Oratai Weeranantanapan, Thiranut Jaroonwitchawan, et al. (2016). Human Embryonic Stem Cells: A Model for the Study of Neural Development and Neurological Diseases. Stem Cells International, 2016(1). https://doi.org/10.1155/2016/2958210

Human Embryonic Stem Cells: A Model for the Study of Neural Development and Neurological Diseases

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