Dry Eye Syndrome in Patients with Diabetes Mellitus: Prevalence, Etiology, and Clinical Characteristics

Xinyuan Zhang; Lin Zhao; Shijing Deng; Xuguang Sun; Ningli Wang

doi:10.1155/2016/8201053

journal article Open Access Jan 01, 2016

Dry Eye Syndrome in Patients with Diabetes Mellitus: Prevalence, Etiology, and Clinical Characteristics

Xinyuan Zhang

Lin Zhao

Shijing Deng Xuguang Sun

Ningli Wang

Journal of Ophthalmology Vol. 2016 pp. 1-7 · Wiley

View at Publisher Save 10.1155/2016/8201053

Abstract

There has been substantial progress in our understanding of the ocular surface system/lacrimal function unit in the past 15 years. Keratoconjunctivitis sicca, more commonly referred to as dry eye syndrome (DES), is the most frequently encountered condition and diabetes mellitus (DM) has been identified as one of the leading causes of DES. Poor glycemic control affects both the anterior and the posterior segments of the eye and increasing prevalence of diabetes-associated DES (DMDES) has been reported in recent years. The pathogenesis and specific features of DMDES remain uncertain and interventions are limited to those used in DES. This review outlines the pathogenesis, clinical manifestations, and the current preventive and treatment strategies for diabetes-related DES.

Topics

No keywords indexed for this article. Browse by subject →

References

53

[1]

10.1001/jama.2013.168118

[2]

10.1186/1471-2415-8-10

[3]

Ophthalmologe (1994)

[4]

10.1016/j.optm.2006.08.002

[5]

10.1097/00003226-200007000-00017

[6]

10.1016/j.exer.2008.09.002

[7]

10.1136/bjo.76.3.157

[8]

10.1016/j.ajo.2008.05.016

[9]

The Ocular Surface (2007) 10.1016/s1542-0124(12)70086-1

[10]

10.1097/00003226-200401000-00006

[11]

Investigative Ophthalmology and Visual Science (1981)

[12]

10.1111/j.1444-0938.2008.00309.x

[13]

International Journal of Clinical and Experimental Pathology (2015)

[14]

10.1097/ico.0000000000000163

[15]

Molecular Vision (2013)

[16]

Clinical and Experimental Rheumatology (1994)

[17]

10.1016/s0161-6420(84)34251-8

[18]

10.1186/1756-0500-7-78

[19]

10.1001/archopht.1977.04450120099012

[20]

10.2337/dc14-0860

[21]

10.1016/s0039-6257(00)00203-4

[22]

10.1136/bjo.84.1.19

[23]

10.1016/s0161-6420(00)00599-6

[24]

10.1155/2014/848659

[25]

10.5935/0004-2749.20150041

[26]

10.1007/s12020-009-9208-9

[27]

Molecular Vision (2010)

[28]

10.1001/archophthalmol.2011.364

[29]

Hyperosmolar Saline Is a Proinflammatory Stress on the Mouse Ocular Surface

Lihui Luo, De-Quan Li, Rosa M. Corrales et al.

Eye & Contact Lens: Science & Clinical Pra... 10.1097/01.icl.0000162759.79740.46

[30]

10.1016/j.exer.2005.08.019

[31]

10.1167/iovs.13-12080

[32]

10.1016/s0168-8227(02)00244-9

[33]

10.1016/j.ajo.2004.10.022

[34]

10.2147/opth.s51514

[35]

10.1016/s0161-6420(90)32388-6

[36]

10.1097/00003226-200111000-00004

[37]

10.1001/archopht.118.5.615

[38]

The Ocular Surface (2007) 10.1016/s1542-0124(12)70085-x

[39]

10.3129/i09-015

[40]

Journal of Ophthalmic and Vision Research (2014)

[41]

10.1007/s40123-015-0038-y

[42]

10.1631/jzus.2006.b0675

[43]

Corneal Confocal Microscopy in Dry Eye Treated with Corticosteroids

Edoardo Villani, Elena Garoli, Vittoria Termine et al.

Optometry and Vision Science 10.1097/opx.0000000000000600

[44]

10.1155/2012/789623

[45]

10.4239/wjd.v6.i1.92

[46]

10.1016/j.sjopt.2013.12.003

[47]

10.1097/ico.0000000000000123

[48]

10.2165/00128071-200203060-00002

[49]

British Journal of Ophthalmology (2005) 10.1136/bjo.2004.051391

[50]

International Journal of Pharmaceutical Compounding (2014)

Showing 50 of 53 references

Cited By

131

Smart Contact Lenses for Healthcare Monitoring and Therapy

Xiaohu Liu, Ying Ye · 2024

ACS Nano

The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas

Fu-Shin X. Yu, Patrick S.Y. Lee · 2022

Progress in Retinal and Eye Researc...

Metrics

131

Citations

53

References

Details

Published: Jan 01, 2016
Vol/Issue: 2016
Pages: 1-7
License: View

Authors

X

Xinyuan Zhang