2,4-D poisoning: a review with illustration of two cases

Ashok Kumar Pannu; Atul Saroch; Jatin Agrawal; Navneet Sharma

doi:10.1177/0049475518786834

journal article Jul 17, 2018

2,4-D poisoning: a review with illustration of two cases

Ashok Kumar Pannu Atul Saroch Jatin Agrawal Navneet Sharma

Tropical Doctor Vol. 48 No. 4 pp. 366-368 · SAGE Publications

View at Publisher Save 10.1177/0049475518786834

Abstract

2,4-D (2,4-dichlorphenoxyacetic acid) is a chlorphenoxy group pesticide. Its relative safety and broad leaf selectivity makes it a favourite herbicide of many home gardeners and agricultural workers. Severe systemic toxicity requiring hospital admission and intensive care usually occurs following intentional oral ingestion. 2,4-D poisoning is an under-recognised cause of a potentially lethal toxic syndrome, especially in low- and middle-income countries, where such compounds are widely used in farming and readily available in households. It warrants close monitoring and high-quality supportive care along with plasma alkalinisation or extracorporeal removal of the toxin. We present a short review on 2,4-D poisoning and describe two illustrative cases with significant oral ingestion resulted in early and rapidly developing systemic toxicity. Both patients were admitted to the intensive care unit; one patient was managed with alkaline diuresis and other case required three sessions of haemodialysis.

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Citations

9

References

Details

Published: Jul 17, 2018
Vol/Issue: 48(4)
Pages: 366-368
License: View

Authors

A

Ashok Kumar Pannu

Internal Medicine Assistant Professor, Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India

A

Atul Saroch

Medicine Assistant Professor, Department of Medicine, Post Graduate Institute of Medical Education and Research, Dr. RML Hospital, New Delhi, India

J

Jatin Agrawal

MD Resident Medicine, Department of Medicine, Sardar Patel Medical College, Bikaner, Rajasthan, India

N

Navneet Sharma

Internal Medicine Professor, Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India

Cite This Article

Ashok Kumar Pannu, Atul Saroch, Jatin Agrawal, et al. (2018). 2,4-D poisoning: a review with illustration of two cases. Tropical Doctor, 48(4), 366-368. https://doi.org/10.1177/0049475518786834

2,4-D poisoning: a review with illustration of two cases

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