Measurement properties of the Timed Up &amp; Go test in patients with COPD

Rafael Mesquita; Sarah Wilke; Dionne E Smid; Daisy JA Janssen; Frits ME Franssen; Vanessa S Probst; Emiel FM Wouters; Jean WM Muris; Fabio Pitta; Martijn A Spruit

doi:10.1177/1479972316647178

journal article Jul 08, 2016

Measurement properties of the Timed Up & Go test in patients with COPD

Rafael Mesquita Sarah Wilke Dionne E Smid Daisy JA Janssen Frits ME Franssen Vanessa S Probst Emiel FM Wouters Jean WM Muris Fabio Pitta Martijn A Spruit

Chronic Respiratory Disease Vol. 13 No. 4 pp. 344-352 · SAGE Publications

View at Publisher Save 10.1177/1479972316647178

Abstract

We aimed to investigate the construct validity of the Timed Up & Go (TUG) test in chronic obstructive pulmonary disease (COPD), to identify characteristics related to an abnormal TUG time and to examine the responsiveness of the TUG to pulmonary rehabilitation (PR). TUG time was assessed before and after comprehensive PR in 500 COPD patients, and compared cross-sectionally in 100 non-COPD subjects. Physical health outcomes, mental health outcomes, symptom-related outcomes and multidimensional indices were assessed in COPD patients only. Good convergent and discriminant validity was demonstrated by fair-to-moderate correlation with physical health outcomes, symptom-related outcomes and multidimensional indices ( rs = 0.18–0.70) and by little correlation with mental health outcomes ( rs = 0.21–0.26). COPD patients had a worse TUG time than non-COPD subjects, demonstrating known-groups validity. A TUG time of 11.2 seconds had good sensitivity (0.75) and specificity (0.83) for identifying patients with a baseline 6-minute walk distance <350 m. TUG time improved after PR ( p < 0.0001) and a change of 0.9–1.4 seconds was identified as clinically important. The TUG is valid and responsive in COPD. An abnormal result is indicative of poor health outcomes. This simple test provides valuable information and can be adopted in clinical and research settings.

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Details

Published: Jul 08, 2016
Vol/Issue: 13(4)
Pages: 344-352
License: View

Authors

R

Rafael Mesquita

Department of Research and Education, CIRO, Horn, The Netherlands; Department of Respiratory Medicine, Maastricht University Medical Center+ (MUMC+), Maastricht, The Netherlands

S

Sarah Wilke

Department of Research and Education, CIRO, Horn, The Netherlands

D

Dionne E Smid

Department of Research and Education, CIRO, Horn, The Netherlands

D

Daisy JA Janssen

Department of Research and Education, CIRO, Horn, The Netherlands

F

Frits ME Franssen

Department of Research and Education, CIRO, Horn, The Netherlands

V

Vanessa S Probst

Center for Research in Health Sciences, University North of Paraná (UNOPAR), Londrina, Brazil; Laboratory of Research in Respiratory Physiotherapy, Department of Physiotherapy, State University of Londrina (UEL), Londrina, Brazil

E

Emiel FM Wouters

Department of Research and Education, CIRO, Horn, The Netherlands; Department of Respiratory Medicine, Maastricht University Medical Center+ (MUMC+), Maastricht, The Netherlands

J

Jean WM Muris

Caphri School of Public Health and Primary Care, Department of Family Medicine, Maastricht University, Maastricht, The Netherlands

F

Fabio Pitta

Laboratory of Research in Respiratory Physiotherapy, Department of Physiotherapy, State University of Londrina (UEL), Londrina, Brazil

M

Martijn A Spruit

Department of Research and Education, CIRO, Horn, The Netherlands

Cite This Article

Rafael Mesquita, Sarah Wilke, Dionne E Smid, et al. (2016). Measurement properties of the Timed Up & Go test in patients with COPD. Chronic Respiratory Disease, 13(4), 344-352. https://doi.org/10.1177/1479972316647178

Measurement properties of the Timed Up &amp; Go test in patients with COPD

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