Abstract
Background: Among non-communicable disorders (NCDs), stroke remains the second leading cause of death and the third leading cause of death and disability combined (as expressed by disability-adjusted life-years lost—DALYs) in the world. Aims: The study was aimed to estimate global, regional and nationa burden of stroke and its risk factors from 1990 to 2021. Methods: Finding presented in this paper were derived mainly from the Global Burden of Disease 2021 Study on stroke burden published in The Lancet Neurology 2024:23:973-1003. Results: The estimated global cost of stroke is over US$890 billion (0.66% of the global GDP). From 1990 to 2021, the burden (in terms of the absolute number of cases) increased substantially (70.0% increase in incident strokes, 44.0% deaths from stroke, 86.0% prevalent strokes, and 32% DALYs), with the bulk of the global stroke burden (87.0% of deaths and 89.0% of DALYs) residing in lower-income and lower-middle-income countries (LMICs). Stroke attributable to metabolic risks constituted 69.0% of all strokes, environmental risks constituted 37.0%, and behavioral risks constituted 35.0%. Conclusion: This World Stroke Organization (WSO) Global Stroke Fact Sheet 2025 provides the most updated information that can be used to inform communication with all internal and external stakeholders; all statistics have been reviewed and approved for use by the WSO Executive Committee and leaders from the Global Burden of Disease research group.
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References
12
[1]
Global, regional, and national burden of stroke and its risk factors, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Valery L Feigin, Melsew Dagne Abate, Yohannes Habtegiorgis Abate et al.

The Lancet Neurology 10.1016/s1474-4422(24)00369-7
[2]
Pragmatic solutions to reduce the global burden of stroke: a World Stroke Organization–Lancet Neurology Commission

Valery L Feigin, Mayowa O Owolabi, Foad Abd-Allah et al.

The Lancet Neurology 10.1016/s1474-4422(23)00277-6
[3]
[4]
Tackling NCDs: best buys and other recommended interventions for the prevention and control of noncommunicable diseases. 2nd ed. Geneva: World Health Organization, 2024, https://iris.who.int/bitstream/handle/10665/376624/9789240091078-eng.pdf?sequence=1 (accessed 10 October 2024).
[5]
Brayne C. The Lancet Neurology 20th Anniversary Lecture: Professor Carol Brayne CBE, https://www.dementiaresearcher.nihr.ac.uk/the-lancet-neurology-20th-anniversary-lecture-professor-carol-brayne-cbe/ (2022, accessed 10 October 2024).
[7]
World Health Organization. Food systems for health: information brief. Geneva: World Health Organization, 2021, https://www.who.int/publications/i/item/9789240035263 (accessed 10 October 2024).
[8]
World Health Organization. Draft intersectoral global action plan on epilepsy and other neurological disorders 2022 – 2031, https://cdn.who.int/media/docs/default-source/mental-health/dementia/global-targets-and-indicators_summary.pdf?sfvrsn=33602d19_8 (accessed 24 June 2023).
[9]
Stahmeyer JT Dtsch Arztebl Int (2019)
[10]
Stacey N Prev Med (2017)
[12]
Martins S Int J Stroke (2021)
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Metrics
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Citations
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References
Details
Published
Jan 03, 2025
Vol/Issue
20(2)
Pages
132-144
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Cite This Article
Valery L Feigin, Michael Brainin, Bo Norrving, et al. (2025). World Stroke Organization: Global Stroke Fact Sheet 2025. International Journal of Stroke, 20(2), 132-144. https://doi.org/10.1177/17474930241308142
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