CREB1/CRTC2 regulated tubular epithelial-derived exosomal miR-93-3p promotes kidney injury induced by calcium oxalate via activating M1 polarization and macrophage extracellular trap formation

Yushi Sun; Bojun Li; Baofeng Song; Yuqi Xia; Xiangjun Zhou; Fangyou Lin; Ting Rao; Fan Cheng

doi:10.1186/s12951-025-03246-9

journal article Open Access Mar 12, 2025

CREB1/CRTC2 regulated tubular epithelial-derived exosomal miR-93-3p promotes kidney injury induced by calcium oxalate via activating M1 polarization and macrophage extracellular trap formation

Yushi Sun Bojun Li Baofeng Song Yuqi Xia Xiangjun Zhou

Fangyou Lin Ting Rao Fan Cheng

Journal of Nanobiotechnology Vol. 23 No. 1 · Springer Science and Business Media LLC

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Details

Published: Mar 12, 2025
Vol/Issue: 23(1)
License: View

Authors

Y

Yushi Sun

HSBC Business School Peking University Shenzhen China

Department of Plant Breeding and Genetics (L.-W.C., X.Z., S.B., L.L.) and Robert W. Holley Center for Agriculture and Health, United States Department of Agriculture-Agricultural Research Service (L.L.), Cornell University, Ithaca, New York 14853; United States Department of Agriculture-Agricultural Research Service, Arkansas Children’s Nutrition Center, Little Rock, Arkansas 72202 (X.W., R.L.P.)

Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, P.R. China

F

Fan Cheng

Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, P.R. China

Funding

National Natural Science Foundation of China Award: 82270802

the Fundamental Research Funds for the Central Universities Award: 2042023kf0022

The Open Project of Hubei Key Laboratory Award: 2023KFZZ009

Cite This Article

Yushi Sun, Bojun Li, Baofeng Song, et al. (2025). CREB1/CRTC2 regulated tubular epithelial-derived exosomal miR-93-3p promotes kidney injury induced by calcium oxalate via activating M1 polarization and macrophage extracellular trap formation. Journal of Nanobiotechnology, 23(1). https://doi.org/10.1186/s12951-025-03246-9

CREB1/CRTC2 regulated tubular epithelial-derived exosomal miR-93-3p promotes kidney injury induced by calcium oxalate via activating M1 polarization and macrophage extracellular trap formation

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