Biomarkers associated with low, moderate, and high vastus lateralis muscle hypertrophy following 12 weeks of resistance training

Christopher B. Mobley; Cody T. Haun; Paul A. Roberson; Petey W. Mumford; Wesley C. Kephart; Matthew A. Romero; Shelby C. Osburn; Christopher G. Vann; Kaelin C. Young; Darren T. Beck; Jeffrey S. Martin; Christopher M. Lockwood; Michael D. Roberts

doi:10.1371/journal.pone.0195203

journal article Open Access Apr 05, 2018

Biomarkers associated with low, moderate, and high vastus lateralis muscle hypertrophy following 12 weeks of resistance training

Christopher B. Mobley Cody T. Haun Paul A. Roberson Petey W. Mumford Wesley C. Kephart Matthew A. Romero Shelby C. Osburn Christopher G. Vann

Kaelin C. Young Darren T. Beck Jeffrey S. Martin Christopher M. Lockwood Michael D. Roberts

PLoS ONE Vol. 13 No. 4 pp. e0195203 · Public Library of Science (PLoS)

View at Publisher Save 10.1371/journal.pone.0195203

Topics

No keywords indexed for this article. Browse by subject →

References

50

[1]

C McGlory "Skeletal muscle and resistance exercise training; the role of protein synthesis in recovery and remodeling" J Appl Physiol (1985) (2017) 10.1152/japplphysiol.00613.2016

[2]

T Snijders "Satellite cells in human skeletal muscle plasticity" Front Physiol (2015) 10.3389/fphys.2015.00283

[3]

VC Figueiredo "Ribosome biogenesis adaptation in resistance training-induced human skeletal muscle hypertrophy" Am J Physiol Endocrinol Metab (2015) 10.1152/ajpendo.00050.2015

[4]

MJ Stec "Ribosome biogenesis may augment resistance training-induced myofiber hypertrophy and is required for myotube growth in vitro" Am J Physiol Endocrinol Metab (2016) 10.1152/ajpendo.00486.2015

[5]

Y Wen "Ribosome Biogenesis is Necessary for Skeletal Muscle Hypertrophy" Exerc Sport Sci Rev (2016) 10.1249/jes.0000000000000082

[6]

T Chaillou "Ribosome biogenesis: emerging evidence for a central role in the regulation of skeletal muscle mass" J Cell Physiol (2014) 10.1002/jcp.24604

[7]

GA Nader "Ribosomes 'muscle up' postnatal muscle growth" J Physiol (2014) 10.1113/jphysiol.2014.284828

[8]

L Yang "Regulation of SirT1-nucleomethylin binding by rRNA coordinates ribosome biogenesis with nutrient availability" Mol Cell Biol (2013) 10.1128/mcb.00476-13

[9]

P Percipalle "The chromatin remodelling complex WSTF-SNF2h interacts with nuclear myosin 1 and has a role in RNA polymerase I transcription" EMBO Rep (2006) 10.1038/sj.embor.7400657

[10]

JK Petrella "Potent myofiber hypertrophy during resistance training in humans is associated with satellite cell-mediated myonuclear addition: a cluster analysis" J Appl Physiol (1985) (2008) 10.1152/japplphysiol.01215.2007

[11]

A Thalacker-Mercer "Cluster analysis reveals differential transcript profiles associated with resistance training-induced human skeletal muscle hypertrophy" Physiol Genomics (2013) 10.1152/physiolgenomics.00167.2012

[12]

Data clustering: 50 years beyond K-means

Anil K. Jain

Pattern Recognition Letters 2010 10.1016/j.patrec.2009.09.011

[13]

MM Bamman "Cluster analysis tests the importance of myogenic gene expression during myofiber hypertrophy in humans" J Appl Physiol (1985) (2007) 10.1152/japplphysiol.00024.2007

[14]

F Haddad "IL-6-induced skeletal muscle atrophy" J Appl Physiol (1985) (2005) 10.1152/japplphysiol.01026.2004

[15]

O Zamir "Tumour necrosis factor (TNF) and interleukin-1 (IL-1) induce muscle proteolysis through different mechanisms" Mediators Inflamm (1992) 10.1155/s0962935192000371

[16]

CJ Mitchell "Muscular and systemic correlates of resistance training-induced muscle hypertrophy" PLoS One (2013) 10.1371/journal.pone.0078636

[17]

CB Mobley "Effects of Whey, Soy or Leucine Supplementation with 12 Weeks of Resistance Training on Strength, Body Composition, and Skeletal Muscle and Adipose Tissue Histological Attributes in College-Aged Males" Nutrients (2017) 10.3390/nu9090972

[18]

MK Menon "Ultrasound assessment of lower limb muscle mass in response to resistance training in COPD" Respir Res (2012) 10.1186/1465-9921-13-119

[19]

Distribution of different fiber types in human skeletal muscles: Effects of aging studied in whole muscle cross sections

Jan Lexell, Karin Henriksson‐Larsén, Bengt Winblad et al.

Muscle & Nerve 1983 10.1002/mus.880060809

[20]

MR Rhea "A comparison of linear and daily undulating periodized programs with equated volume and intensity for strength" J Strength Cond Res (2002)

[21]

G Haff "Essentials of strength training and conditioning" (2016)

[22]

M Ahmed "Validation of a Tablet Application for Assessing Dietary Intakes Compared with the Measured Food Intake/Food Waste Method in Military Personnel Consuming Field Rations" Nutrients (2017) 10.3390/nu9030200

[23]

J Antonio "A high protein diet (3.4 g/kg/d) combined with a heavy resistance training program improves body composition in healthy trained men and women—a follow-up investigation" J Int Soc Sports Nutr (2015) 10.1186/s12970-015-0100-0

[24]

J Antonio "The effects of consuming a high protein diet (4.4 g/kg/d) on body composition in resistance-trained individuals" J Int Soc Sports Nutr (2014) 10.1186/1550-2783-11-19

[25]

JK Petrella "Efficacy of myonuclear addition may explain differential myofiber growth among resistance-trained young and older men and women" Am J Physiol Endocrinol Metab (2006) 10.1152/ajpendo.00190.2006

[26]

AJ Murton "Resistance exercise and the mechanisms of muscle mass regulation in humans: acute effects on muscle protein turnover and the gaps in our understanding of chronic resistance exercise training adaptation" Int J Biochem Cell Biol (2013) 10.1016/j.biocel.2013.07.005

[27]

DT Wang "Resveratrol prevents TNF-alpha-induced muscle atrophy via regulation of Akt/mTOR/FoxO1 signaling in C2C12 myotubes" Int Immunopharmacol (2014) 10.1016/j.intimp.2014.02.002

[28]

J De Larichaudy "TNF-alpha- and tumor-induced skeletal muscle atrophy involves sphingolipid metabolism" Skelet Muscle (2012) 10.1186/2044-5040-2-2

[29]

P Munoz-Canoves "Interleukin-6 myokine signaling in skeletal muscle: a double-edged sword?" FEBS J (2013) 10.1111/febs.12338

[30]

DS Raj "Interleukin-6 modulates hepatic and muscle protein synthesis during hemodialysis" Kidney Int (2008) 10.1038/ki.2008.21

[31]

SM Pasiakos "Assessment of skeletal muscle proteolysis and the regulatory response to nutrition and exercise" IUBMB Life (2014) 10.1002/iub.1291

[32]

G Ben-Nissan "Regulating the 20S proteasome ubiquitin-independent degradation pathway" Biomolecules (2014) 10.3390/biom4030862

[33]

JS Greiwe "Resistance exercise decreases skeletal muscle tumor necrosis factor alpha in frail elderly humans" FASEB J (2001) 10.1096/fj.00-0274com

[34]

CP Lambert "Exercise but not diet-induced weight loss decreases skeletal muscle inflammatory gene expression in frail obese elderly persons" J Appl Physiol (1985) (2008) 10.1152/japplphysiol.00006.2008

[35]

I Sinha-Hikim "Testosterone-induced muscle hypertrophy is associated with an increase in satellite cell number in healthy, young men" Am J Physiol Endocrinol Metab (2003) 10.1152/ajpendo.00370.2002

[36]

I Sinha-Hikim "Testosterone-induced increase in muscle size in healthy young men is associated with muscle fiber hypertrophy" Am J Physiol Endocrinol Metab (2002) 10.1152/ajpendo.00502.2001

[37]

AA Ferrando "Testosterone injection stimulates net protein synthesis but not tissue amino acid transport" Am J Physiol (1998)

[38]

RC Griggs "Effect of testosterone on muscle mass and muscle protein synthesis" J Appl Physiol (1985) (1989) 10.1152/jappl.1989.66.1.498

[39]

BJ Schoenfeld "Postexercise hypertrophic adaptations: a reexamination of the hormone hypothesis and its applicability to resistance training program design" J Strength Cond Res (2013) 10.1519/jsc.0b013e31828ddd53

[40]

C McFarlane "Myostatin signals through Pax7 to regulate satellite cell self-renewal" Exp Cell Res (2008) 10.1016/j.yexcr.2007.09.012

[41]

WE Taylor "Myostatin inhibits cell proliferation and protein synthesis in C2C12 muscle cells" Am J Physiol Endocrinol Metab (2001) 10.1152/ajpendo.2001.280.2.e221

[42]

VJ Dalbo "Effects of pre-exercise feeding on serum hormone concentrations and biomarkers of myostatin and ubiquitin proteasome pathway activity" Eur J Nutr (2013) 10.1007/s00394-012-0349-x

[43]

E Louis "Time course of proteolytic, cytokine, and myostatin gene expression after acute exercise in human skeletal muscle" J Appl Physiol (1985) (2007) 10.1152/japplphysiol.00679.2007

[44]

JS Kim "Load-mediated downregulation of myostatin mRNA is not sufficient to promote myofiber hypertrophy in humans: a cluster analysis" J Appl Physiol (1985) (2007) 10.1152/japplphysiol.01194.2006

[45]

JJ Hulmi "Acute and long-term effects of resistance exercise with or without protein ingestion on muscle hypertrophy and gene expression" Amino Acids (2009) 10.1007/s00726-008-0150-6

[46]

HK Hammond "Heart size and maximal cardiac output are limited by the pericardium" Am J Physiol (1992)

[47]

JP White "Overload-induced skeletal muscle extracellular matrix remodelling and myofibre growth in mice lacking IL-6" Acta Physiol (Oxf) (2009) 10.1111/j.1748-1716.2009.02029.x

[48]

What is the relationship between the acute muscle protein synthesis response and changes in muscle mass?

Cameron J. Mitchell, Tyler A. Churchward-Venne, David Cameron-Smith et al.

Journal of Applied Physiology 2015 10.1152/japplphysiol.00609.2014

[49]

G Terzis "Resistance exercise-induced increase in muscle mass correlates with p70S6 kinase phosphorylation in human subjects" Eur J Appl Physiol (2008) 10.1007/s00421-007-0564-y

[50]

DL Mayhew "Translational signaling responses preceding resistance training-mediated myofiber hypertrophy in young and old humans" J Appl Physiol (1985) (2009) 10.1152/japplphysiol.91234.2008

Metrics

98

Citations

50

References

Details

Published: Apr 05, 2018
Vol/Issue: 13(4)
Pages: e0195203
License: View

Authors

C

Christopher B. Mobley

C

Cody T. Haun

Fitomics, LLC., Pelham, AL 35124, USA

Department of Health & Exercise Science Colorado State University Fort Collins Colorado USA; Center for Healthy Aging Colorado State University Fort Collins Colorado USA

C

Christopher G. Vann

Duke Molecular Physiology Institute Duke University Durham North Carolina USA

Christopher M. Lockwood

M

Michael D. Roberts

School of Kinesiology, Auburn University, Auburn, AL 36849, USA

Funding

Hilmar Ingredients

Bionutritional Research Group

Cite This Article

Christopher B. Mobley, Cody T. Haun, Paul A. Roberson, et al. (2018). Biomarkers associated with low, moderate, and high vastus lateralis muscle hypertrophy following 12 weeks of resistance training. PLoS ONE, 13(4), e0195203. https://doi.org/10.1371/journal.pone.0195203

Biomarkers associated with low, moderate, and high vastus lateralis muscle hypertrophy following 12 weeks of resistance training

You May Also Like