An Increasing Incidence of Upper Gastrointestinal Disorders Over 23 Years: A Prospective Population-Based Study in Sweden

Anna Andreasson; Nicholas J. Talley; Marjorie M. Walker; Michael P. Jones; Loretta G. Platts; Bengt Wallner; Lars Kjellström; Per M. Hellström; Anna Forsberg; Lars Agréus

doi:10.14309/ajg.0000000000000972

journal article Oct 07, 2020

An Increasing Incidence of Upper Gastrointestinal Disorders Over 23 Years: A Prospective Population-Based Study in Sweden

Anna Andreasson

Nicholas J. Talley

Marjorie M. Walker Michael P. Jones

Loretta G. Platts

Bengt Wallner Lars Kjellström Per M. Hellström

Anna Forsberg Lars Agréus

American Journal of Gastroenterology Vol. 116 No. 1 pp. 210-213 · Ovid Technologies (Wolters Kluwer Health)

View at Publisher Save 10.14309/ajg.0000000000000972

Abstract

INTRODUCTION:
We hypothesized that the prevalence of functional dyspepsia and gastroesophageal reflux disease in the community may be increasing.

METHODS:
Randomly selected adults were surveyed on 4 occasions: 1988 (n = 1,151, 21–79 years, response rate [rr] = 90%), 1989 (n = 1,097, 22–80 years, rr = 87%), 1995 (n = 1,139, 20–85 years, rr = 76%), and 2011 (n = 1,175, 20–93 years, rr = 63%).

RESULTS:
In functional dyspepsia, the odds of postprandial distress syndrome tripled over 23 years' follow-up (odds ratio [OR]: 3.55; 95% confidence interval [CI]: 2.60–4.84, mixed-effect regression analysis), whereas a small decrease in epigastric pain syndrome was observed (OR: 0.65, 95% CI: 0.42–1.00). The odds of reporting gastroesophageal reflux disease doubled (OR: 2.02; 95% CI: 1.50–2.73).

DISCUSSION:
The underlying mechanisms behind the increase in postprandial distress syndrome and gastroesophageal reflux disease remain to be determined.

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References

10

[1]

Agreus "Natural history of gastroesophageal reflux disease and functional abdominal disorders: A population-based study" Am J Gastroenterol (2001) 10.1111/j.1572-0241.2001.04680.x

[2]

Ronkainen "High prevalence of gastroesophageal reflux symptoms and esophagitis with or without symptoms in the general adult Swedish population: A kalixanda study report" Scand J Gastroenterol (2005) 10.1080/00365520510011579

[3]

Aziz "Epidemiology, clinical characteristics, and associations for symptom-based rome IV functional dyspepsia in adults in the USA, Canada, and the UK: A cross-sectional population-based study" Lancet Gastroenterol Hepatol (2018) 10.1016/s2468-1253(18)30003-7

[4]

Agreus "Reproducibility and validity of a postal questionnaire. The abdominal symptom study" Scand J Prim Health Care (1993) 10.3109/02813439308994840

[5]

Towards a healthy stomach? Helicobacter pylori prevalence has dramatically decreased over 23 years in adults in a Swedish community

Lars Agréus, Per M Hellström, Nicholas J Talley et al.

United European Gastroenterology Journal 2016 10.1177/2050640615623369

[6]

Drossman "Rome IV-functional GI disorders: Disorders of gut-brain interaction" Gastroenterology (2016) 10.1053/j.gastro.2016.03.035

[7]

Ford "Global prevalence of, and risk factors for, uninvestigated dyspepsia: A meta-analysis" Gut (2015) 10.1136/gutjnl-2014-307843

[8]

Ramstrom "Patterns of smoking and snus use in Sweden: Implications for public health" Int J Environ Res Public Health (2016) 10.3390/ijerph13111110

[9]

Tack "Symptom pattern and pathophysiological correlates of weight loss in tertiary-referred functional dyspepsia" Neurogastroenterol Motil (2010) 10.1111/j.1365-2982.2008.01240.x

[10]

Waller Lidstrom "Time trends of comparative self-rated health in adults aged 25-34 in the Northern Sweden MONICA study, 1990–2014" PLoS One (2017) 10.1371/journal.pone.0187896

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Details

Published: Oct 07, 2020
Vol/Issue: 116(1)
Pages: 210-213

Authors

A

Anna Andreasson

Stress Research Institute, Department of Psychology, Stockholm University, Stockholm, Sweden;; Department of Psychology, Macquarie University, North Ryde, Australia;; Department of Medicine Solna, Karolinska Institutet, Sweden;

N

Nicholas J. Talley

Faculty of Health and Medicine, University of Newcastle, Newcastle, Australia;; NHMRC Centre of Research Excellence in Digestive Health, Newcastle, Australia;

M

Marjorie M. Walker

Faculty of Health and Medicine, University of Newcastle, Newcastle, Australia;; NHMRC Centre of Research Excellence in Digestive Health, Newcastle, Australia;

M

Michael P. Jones

Department of Psychology, Macquarie University, North Ryde, Australia;

L

Loretta G. Platts

Stress Research Institute, Department of Psychology, Stockholm University, Stockholm, Sweden;

B

Bengt Wallner

Umeå University, Umeå, Sweden;

L

Lars Kjellström

Gastromottagningen City, Stockholm, Sweden;

P

Per M. Hellström

Uppsala University, Uppsala, Sweden;

A

Anna Forsberg

Department of Medicine Solna, Karolinska Institutet, Sweden;

L

Lars Agréus

Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.

Cite This Article

Anna Andreasson, Nicholas J. Talley, Marjorie M. Walker, et al. (2020). An Increasing Incidence of Upper Gastrointestinal Disorders Over 23 Years: A Prospective Population-Based Study in Sweden. American Journal of Gastroenterology, 116(1), 210-213. https://doi.org/10.14309/ajg.0000000000000972

An Increasing Incidence of Upper Gastrointestinal Disorders Over 23 Years: A Prospective Population-Based Study in Sweden

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