journal article Open Access Sep 03, 2018

Antibiotic Residue in the Aquatic Environment: Status in Africa

Open Chemistry Vol. 16 No. 1 pp. 890-903 · Walter de Gruyter GmbH
View at Publisher Save 10.1515/chem-2018-0099
Abstract
AbstractInformation on the presence of antibiotics is sparse for all types of water in Africa, including groundwater, surface water, effluent of wastewater treatment plants (WWTPs) and municipal potable water. With the relatively high sales of different antibiotics to treat infectious diseases in the human population of Africa, the residual of the antibiotics is bound to be released through excretion via urine or fecal matter in parallel to the high sales. This article reviews the published analysis on the occurrence of antibiotics in the environment particularly in the aquatic environment in some countries in Africa. In general, sulfamethoxazole was the most commonly detected in Africa surface water (with eight reports from four countries) at a concentration range of 0.00027 – 39 μgL-1. Wastewater analysis is believed to give an early warning for preventing epidemics. Thus, we discuss the associated level of antibiotic resistance to some prevalent diseases in Africa whose aetiological agents can develop antibiotic resistance due to exposure to antibiotic residue in water. This is important because of rising population of immuno-deficient African residents ravaged by HIV/AIDS, poor nutrition and less efficient sanitation systems.
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References
220
[1]
"Development of an analytical method to determine avermectins in water, sediments and soils using liquid chromatography–tandem mass spectrometry" J. Chromatogr. Sci. (2008) 10.1016/j.chroma.2008.09.081
[2]
"Occurrence, partition and removal of pharmaceuticals in sewage water and sludge during wastewater treatment" Water Res. (2011) 10.1016/j.watres.2010.11.010
[3]
"Tuberculosis in Africa: learning from pathogenesis for biomarker identification" Cell Host Microbe. (2008) 10.1016/j.chom.2008.08.002
[4]
(2013)
[5]
"National surveillance programme on susceptibility patterns of respiratory pathogens in South Africa: moxifloxacin compared with eight other antimicrobial agents" J. Clin. Pathol. (2003) 10.1136/jcp.56.5.344
[6]
"Environmental risk and toxicology of human and veterinary waste pharmaceutical exposure to wild aquatic host–parasite relationships" Environ. Toxicol. Pharmacol. (2009) 10.1016/j.etap.2008.11.004
[7]
"The fate of pharmaceuticals and personal care products (PPCPs), endocrine disrupting contaminants (EDCs), metabolites and illicit drugs in a WWTW and environmental waters" Chemosphere (2017) 10.1016/j.chemosphere.2017.01.101
[8]
"Toxicological relevance of pharmaceuticals in drinking water" Environ. Sci. Technol. (2010) 10.1021/es1004895
[9]
"Acute toxicity to freshwater organisms of antiparasitic drugs for veterinary use" Environ. Toxicol. (2005) 10.1002/tox.20078
[10]
"Qualitative analysis of the presence of emerging contaminants in water supplies for human use: a case study of the Guilherme de Azevedo reservoir in Caruaru (PE, Brazil)" Int. J. Adv. Oper. Manag. (2014)
[11]
"Estimating the global burden of multidrug-resistant tuberculosis among prevalent cases of tuberculosis" Int. J. Tuberc. Lung Dis. (2017) 10.5588/ijtld.16.0110
[12]
"Occurrence of antibiotics as emerging contaminant substances in aquatic environment" Int. J. Environ. Health Res. (2013) 10.1080/09603123.2012.733934
[13]
"Quantitative PCR monitoring of antibiotic resistance genes and bacterial pathogens in three European artificial groundwater recharge systems" Appl. Environ. Microbiol. (2009) 10.1128/aem.01649-08
[14]
"Prevalence of Streptococcus pneumonia in patients diagnosed with pneumonia by culture and PCR" Life Sci. J. (2013)
[15]
"Performance Evaluation Of Activated Sludge Process For Treating Pharmaceutical Wastewater Contaminated With B-Lactam Antibiotics" Journal of Industrial Pollution Control (2015)
[16]
(2014)
[17]
"Investment in Agricultural Sector: Implication for Poverty Reduction in Nigeria (1985-2012)" Am. J. Bus. Soc. (2016)
[18]
"Investment in Agricultural Sector: Implication for Poverty Reduction in Nigeria (1985-2012)" Am. J. Bus. Soc. (2016)
[19]
"Occurrence of selected pharmaceuticals in water and sediment of Umgeni River, KwaZulu-Natal, South Africa" Environ. Sci. Pollut. Res. (2015) 10.1007/s11356-015-4217-0
[20]
"The environmental release and fate of antibiotics" Mar. Pollut. Bull. (2014) 10.1016/j.marpolbul.2014.01.005
[21]
"The effectiveness of sewage treatment processes to remove faecal pathogens and antibiotic residues" J. Environ. Sci. Health A (2012) 10.1080/10934529.2012.637432
[22]
"Toxicological relevance of pharmaceuticals in drinking water" Environ. Sci. Technol. (2010) 10.1021/es1004895
[23]
Drugs, Parasitol. Today (1994) 10.1016/0169-4758(94)90234-8
[24]
Antibiotic Uptake by Vegetable Crops from Manure-Applied Soils

Dong Hee Kang, Satish Gupta, Carl Rosen et al.

Journal of Agricultural and Food Chemistry 2013 10.1021/jf404045m
[25]
"Multi-residue determination of 115 veterinary drugs and pharmaceutical residues in milk powder, butter, fish tissue and eggs using liquid chromatography–tandem mass spectrometry" Anal. Chim. Acta (2015) 10.1016/j.aca.2015.04.013
[26]
"Antimicrobial susceptibility profile of selected bacteraemic pathogens from private institutions in South Africa" S. Afr. Med. J. (2007)
[27]
"Barceló D., Determination of antimicrobial residues and metabolites in the aquatic environment by liquid chromatography tandem mass spectrometry" Anal. Bioanal. Chem. (2006) 10.1007/s00216-006-0444-z
[28]
"Pharmaceuticals and illicit drugs in wastewater samples in north-eastern Tunisia" Environ. Sci. Pollut. Res. (2017)
[29]
"Determination of oxytetracycline residues in untreated and treated drinking water in Bindura town by RP-HPLC-UV visible spectrometry after ultrasonic assisted dispersive solid phase extraction (UA-DSPE)" World. J. Pharm. Res. (2014)
[30]
"The influence of antibiotics on the immune system II. Modulation of fish leukocyte responses in culture" Vet. Immunol. Immunopathol. (1985) 10.1016/0165-2427(85)90075-3
[31]
Global trends in antimicrobial use in food animals

Thomas P. Van Boeckel, Charles Brower, Marius Gilbert et al.

Proceedings of the National Academy of Sciences 2015 10.1073/pnas.1503141112
[32]
"Prevalence of antibiotic resistance genes and their relationship with antibiotics in the Huangpu River and the drinking water sources, Shanghai, China, Sci" Total Environ. (2013)
[33]
"Mycobacteria in municipal wastewater treatment and reuse: Microbial diversity for screening the occurrence of clinically and environmentally relevant species in rrid regions" Environ. Sci. Technol. (2017) 10.1021/acs.est.6b05580
[34]
"Occurrence patterns of pharmaceutical residues in wastewater, surface water and groundwater of Nairobi and Kisumu city, Kenya" Chemosphere (2016) 10.1016/j.chemosphere.2016.01.095
[35]
Pneumonia ‘superbug’ causes shivers in SA (2014)
[36]
"Occurrence of antibiotics in wastewater treatment facilities in Wisconsin" USA, Sci. Total Environ. (2006) 10.1016/j.scitotenv.2005.06.030
[37]
"Occurrence, partition and removal of pharmaceuticals in sewage water and sludge during wastewater treatment" Water Res. (2011) 10.1016/j.watres.2010.11.010
[38]
"Research advancement of ecotoxicity of tetracycline antibiotics" J. Agric. Environ. Sci. (2008)
[39]
"The occurrence of emerging trace organic chemicals in wastewater effluents in Saudi Arabia" Sci. Total Environ. (2014) 10.1016/j.scitotenv.2014.01.093
[40]
"Estimating the global burden of multidrug-resistant tuberculosis among prevalent cases of tuberculosis" Int. J. Tuberc. Lung Dis. (2017) 10.5588/ijtld.16.0110
[41]
(2005)
[42]
(2015)
[43]
"Toxicological assessment of hospital wastewater in different treatment processes" Environ. Sci. Pollut. Res. (2015)
[44]
"Antimicrobial drug resistance trends of bacteremia isolates in a rural hospital in southern Mozambique" Am. J. Trop. Med. Hyg. (2010) 10.4269/ajtmh.2010.09-0578
[45]
"The effectiveness of sewage treatment processes to remove faecal pathogens and antibiotic residues" J. Environ. Sci. Health A (2012) 10.1080/10934529.2012.637432
[46]
"The influence of antibiotics on the immune system II. Modulation of fish leukocyte responses in culture" Vet. Immunol. Immunopathol. (1985) 10.1016/0165-2427(85)90075-3
[47]
"Prevalence of antibiotic resistance genes and their relationship with antibiotics in the Huangpu River and the drinking water sources, Shanghai, China, Sci" Total Environ. (2013)
[48]
"Assessing the absorption of new pharmaceuticals" Curr. Top. Med. Chem. (2001) 10.2174/1568026013395010
[49]
"Antibiotic resistance–the need for global solutions" Lancet Infect. Dis. (2013) 10.1016/s1473-3099(13)70318-9
[50]
"Pharmaceuticals as emerging organic contaminants in Umgeni River water system, KwaZulu-Natal, South Africa" Environ. Monit. Assess. (2014) 10.1007/s10661-014-3926-z

Showing 50 of 220 references

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