Regulation of ovarian function: the role of anti-Mullerian hormone
Anti-Mullerian hormone (AMH), also known as Mullerian inhibiting substance, is a member of the transforming growth factor β superfamily of growth and differentiation factors. In contrast to other members of the family, which exert a broad range of functions in multiple tissues, the principal function of AMH is to induce regression of the Mullerian ducts during male sex differentiation. However, the patterns of expression of AMH and its type II receptor in the postnatal ovary indicate that AMH may play an important role in ovarian folliculogenesis. This review describes several in vivo and in vitro studies showing that AMH participates in two critical selection points of follicle development: it inhibits the recruitment of primordial follicles into the pool of growing follicles and also decreases the responsiveness of growing follicles to FSH.
No keywords indexed for this article. Browse by subject →
Florian Böhmer, Katharina Erber · 2022
Kristina W. Olsen, Juan Castillo-Fernandez · 2021
J. Xu, C.V. Bishop · 2016
A. Heather Eliassen, Anne Zeleniuch-Jacquotte · 2016
Alagu Thilagam · 2015
Didier Dewailly, Claus Yding Andersen · 2014
M. Lebbe, T. K. Woodruff · 2013
Jenny A. Visser, Izaäk Schipper · 2012
S. M. Schuh-Huerta, N. A. Johnson · 2011
Aparna Mahakali Zama, Mehmet Uzumcu · 2010
Eric Nilsson, Natalie Rogers · 2007
- Published
- Nov 01, 2002
- Vol/Issue
- 124(5)
- Pages
- 601-609
- License
- View
You May Also Like
Torben Pedersen, HANNAH PETERS · 1968
844 citations
Joseph Saragusty, Amir Arav · 2011
382 citations
Shawn M Briley, Susmita Jasti · 2016
325 citations
Shan Herath, Erin J Williams · 2007
280 citations
R John Aitken · 2020
253 citations