journal article Open Access May 15, 2021

Morphological types of anaemia integrated with distribution of red cell and platelet indices: Study in a rural tertiary healthcare centre

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Abstract
Anaemia is a critical global health problemA good morphological subtyping of anaemia can guide clinician in further patient management. With the advent of automation, red cell and platelet indices are available from the routinely used blood cell counters in the laboratory, these supplemented with peripheral smear examination help in a good categorization of anaemia. Aim of this study is to study the morphological types of anaemias in the adults with the Objectives of Categorization of the anaemias based on morphology and to study the distribution of the red cell and platelet indices in the same.: It was a prospective study conducted in the hematology wing of our central diagnostics over a period of three months and a total of 520 cases, which were morphologically classified according to the analyzer indices and peripheral smear. Distribution of the red cell and platelet indices in the different categories of anaemia were also noted. A majority of the anaemias were microcytic hypochromic in type (67.1%) followed by normocytic normochromic anaemias (26.5%). Increased RDW was seen in microcytic hypochromic anaemias (55%) and normocytic normochromic anaemias (6.9%). The Mean platelet count/ mean platelet volume was increased in microcytic anaemias compared to others. : Anaemias in the rural set up are predominantly of the microcytic in type. A good knowledge of the variation in RBC indices, RDW and platelet /mean platelet volume ratio along with a peripheral smear can help the reporting haematologist identify early stages of iron deficiency anaemia and can give a precise and accurate anaemia categorization at the basic entry level of laboratory investigation. Interpretation of variation in RBC and platelet indices though often neglected can contribute significantly to categorize the anaemia.
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References
21
[1]
Hafizl F, Mahajan S, Koul K, Study of Morphological Patterns of Anemia in Adults.IOSR J Dent Med Sci 2019;18(11):46-50
[3]
Garg M, Sangwan K, Comparision of Automated Analyzer Generated Red Cell Parameters and Histogram with Perpheral Smear in the Diagnosis of Anaemia.Int J Contemp Med Res 2019;6(8):111-6 10.21276/ijcmr.2019.6.8.4
[4]
Singla S, Bedi S, Joshi K, Comparative study of anemia cases based on peripheral blood smears and cell counter generated red cell indices.MedPulse - Int Med J 2017;4:44-8
[5]
Chavda J, Goswami P, Goswami A, RBC Histogram as diagnostic tool in anemias.J Dent Med Sci 2015;14:19-22
[6]
Patel S, Shah M, Patel J, Kumar N, Iron Deficiency Anemia in Moderate to Severely Anaemia Patients.Guj Med J 2009;64(2):15-7
[7]
Jadhav M V, Agarwal S A, Kadgi N V, Khedkar S S, Kulkarni K K, Kudrimoti J K, Utility of automated RBC parameters in evaluation of anemia.Int J Healthcare Biomed Res 2015;3(3):170-81
[8]
Elsayid M, Al-Qahtani A M, Alanazi A, Qureshi S, Determination of the most common morphological patterns of anemia among Saudi anemic patients attending King Abdul-aziz Medical City-Riyadh.Int J Med Public Health 2015;5:301-4 10.4103/2230-8598.165957
[9]
Kumar A, Kushwaha R, Gupta C, Singh US, An analytical study on peripheral blood smears in anemia and correlation with cell countergenerated red cell parameters.J Appl Haematol 2013;4(4):137-44 10.4103/1658-5127.127896
[10]
Adewoyin A, Nwogoh B, Peripheral blood film - A review.Ann Ib Postgrad Med 2014;12:71-9
[11]
Sans-Sabrafen J, Raebel CB, Corrons JLV, La anemia, aspectos enerals del diagnóstico.Hematología Clínica.107-26
[12]
Babu P U, Sai Prasad, Reddy Sudhakar B, Manasa E, R V, .A cross sectional study on morphological pattern of anaemia. IOSR journal of dental and medical sciences 2016;8:68-71 10.9790/0853-1508086871
[13]
Mukaya JE, Ddungu H, Ssali F, Shea T, Crowther MA, Prevalence and morphological types of anaemia and hookworm infestation in the medical Emergency ward, Mulago Hospital, Uganda.S Afr Med J 2009;99:881-6
[14]
Hempel EV, Bollard ER, The Evidence-Based Evaluation of Iron Deficiency Anemia.Med Clin North Am 2016;100(5):1065-75 10.1016/j.mcna.2016.04.015
[15]
Sultana GS, Haque SA, Sultana T, Ahmed AN, Value of red cell distribution width (RDW) and RBC indices in the detection of iron deficiency anaemia.Mymensingh Med J 2013;22(2):370-6
[17]
Chandurkar M, Pendalya S, Clinical profile of patients presenting with anemia in a tertiary care rural hospital of Western Maharashtra.Int J Clin Biomed Res 2017;3(4):74-7 10.5455/ijcbr.2017.34.17
[18]
Cho SY, Yang JJ, Suh JT, Lee WI, Lee HJ, Park TS, Mean platelet volume/platelet count ratio in anemia.Platelets 2013;24(3):244-5 10.3109/09537104.2012.684734
[19]
Singla S, Bedi S, Joshi K, Comparative study of anemia cases based on peripheral blood smears and cell counter generated red cell indices.Med Pulse - Int Med J 2017;4:44-8
[20]
Sandhya I, Muhasin T P, Study of RBC Histogram in Various Anemias.J Evol Med Dent Sci 2014;3:15521-34 10.14260/jemds/2014/4095
[21]
Rao BSS, Santhi V, Rao NM, Grandhi B, Reddy VLM, Siresala P, RBC Histogram as supplementary diagnostic tool with peripheral smear examination in evaluating anemias.Ann Pathol Lab Med 2017;4:668-72 10.21276/apalm.1468
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Published
May 15, 2021
Vol/Issue
8(1)
Pages
45-49
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Cite This Article
Anindita Saha, Archana Shetty, Komala H N (2021). Morphological types of anaemia integrated with distribution of red cell and platelet indices: Study in a rural tertiary healthcare centre. Indian Journal of Pathology and Oncology, 8(1), 45-49. https://doi.org/10.18231/j.ijpo.2021.009