journal article Nov 24, 2013

Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms

Oncotarget Vol. 4 No. 12 pp. 2186-2207 · Impact Journals, LLC
View at Publisher Save 10.18632/oncotarget.1497
Topics

No keywords indexed for this article. Browse by subject →

References
253
[1]
Carrasco "Pathogenesis of myeloma" Annu Rev Pathol (2011) 10.1146/annurev-pathol-011110-130249
[2]
Rajkumar "Monoclonal gammopathy of undetermined significance" Br J Haematol (2006) 10.1111/j.1365-2141.2006.06235.x
[3]
Dewald "Genomic abnormalities in monoclonal gammopathy of undetermined significance" Blood (2002) 10.1182/blood.v100.4.1417.h81602001417_1417_1424
[4]
Walker "The molecular classification of multiple myeloma" Blood (2006) 10.1182/blood-2005-11-013458
[5]
Matsui "Multiple myeloma: a paradigm for translation of the cancer stem cell hypothesis" Anticancer Agents Med Chem (2010) 10.2174/187152010790909344
[6]
Ullah "Cancer multidrug resistance (MDR): a major impediment to effective chemotherapy" Asian Pac J Cancer Prev (2008)
[7]
Gottesman "Mechanisms of cancer drug resistance" Annu Rev Med (2002) 10.1146/annurev.med.53.082901.103929
[8]
Sonneveld "Multidrug resistance in haematological malignancies" J Intern Med (2000) 10.1046/j.1365-2796.2000.t01-1-00689.x
[9]
Janne "Circumventing cancer drug resistance in the era of personalized medicine" Cancer Discov (2012) 10.1158/2159-8290.cd-12-0012
[10]
Swanton "Anti-cancer drug resistance: understanding the mechanisms through the use of integrative genomics and functional RNA interference" Eur J Cancer (2010) 10.1016/j.ejca.2010.03.019
[11]
Raaijmakers "ATP-binding-cassette transporters in hematopoietic stem cells and their utility as therapeutical targets in acute and chronic myeloid leukemia" Leukemia (2007) 10.1038/sj.leu.2404859
[12]
Marie "Drug resistance in hematologic malignancies" Curr Opin Oncol (2001) 10.1097/00001622-200111000-00008
[13]
Cabot "Ceramide glycosylation potentiates cellular multidrug resistance" FASEB J (2001) 10.1096/fj.00-0223com
[14]
Bendall "Oncogenic properties of sphingosine kinases in haematological malignancies" Br J Haematol (2013) 10.1111/bjh.12302
[15]
Ghidoni "Sphingolipid players in the leukemia arena" Biochim Biophys Acta (2006) 10.1016/j.bbamem.2006.06.016
[16]
Xiong "Expression of ABCB5 gene in hematological malignances and its significance" Leuk Lymphoma (2012) 10.3109/10428194.2011.637214
[17]
June "NCI first International Workshop on the biology, prevention, and treatment of relapse after allogeneic hematopoietic stem cell transplantation: report from the committee on the biological considerations of hematological relapse following allogeneic stem cell transplantation unrelated to graft-versus-tumor effects: state of the science" Biol Blood Marrow Transplant (2010) 10.1016/j.bbmt.2010.03.002
[18]
Wang "The resistance mechanisms of proteasome inhibitor bortezomib" Biomarker Research (2013)
[19]
Morgan "A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value" Blood (2010) 10.1182/blood-2010-04-279596
[20]
Munshi "Dysfunctional homologous recombination mediates genomic instability and progression in myeloma" Blood (2009) 10.1182/blood-2007-05-089193
[21]
Chen-Kiang "International Myeloma Working Group molecular classification of multiple myeloma: spotlight review" Leukemia (2009) 10.1038/leu.2009.174
[22]
Davies "Understanding the molecular biology of myeloma and its therapeutic implications" Expert Rev Hematol (2012) 10.1586/ehm.12.51
[23]
Crowley "Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells" Blood (2002) 10.1182/blood.v99.5.1745
[24]
Spencer "The t(4;14) translocation and FGFR3 overexpression in multiple myeloma: prognostic implications and current clinical strategies" Blood Cancer J (2012) 10.1038/bcj.2012.37
[25]
Pilarski "In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression" Blood (2003) 10.1182/blood-2002-06-1675
[26]
Stewart "Clinical outcomes in t(4;14) multiple myeloma: a chemotherapy-sensitive disease characterized by rapid relapse and alkylating agent resistance" J Clin Oncol (2005) 10.1200/jco.2005.17.129
[27]
Greipp "Clinical and biologic implications of recurrent genomic aberrations in myeloma" Blood (2003) 10.1182/blood-2002-10-3017
[28]
Fonseca "Clinical implications of t(11;14)(q13;q32), t(4;14)(p16.3;q32), and -17p13 in myeloma patients treated with high-dose therapy" Blood (2005) 10.1182/blood-2005-04-1411
[29]
Keith Stewart "The t(4;14) is associated with poor prognosis in myeloma patients undergoing autologous stem cell transplant" Br J Haematol (2004) 10.1111/j.1365-2141.2004.04867.x
[30]
Anderson "Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma" N Engl J Med (2008) 10.1056/nejmoa0801479
[31]
Hulin "Bortezomib plus dexamethasone induction improves outcome of patients with t(4;14) myeloma but not outcome of patients with del(17p)" J Clin Oncol (2010) 10.1200/jco.2010.28.3945
[32]
Reece "Bortezomib therapy response is independent of cytogenetic abnormalities in relapsed/refractory multiple myeloma" Leuk Res (2007) 10.1016/j.leukres.2006.08.002
[33]
Reece "Impact of cytogenetics in patients with relapsed or refractory multiple myeloma treated with bortezomib: Adverse effect of 1q21 gains" Leuk Res (2011) 10.1016/j.leukres.2010.05.002
[34]
Bahlis "Influence of cytogenetics in patients with relapsed or refractory multiple myeloma treated with lenalidomide plus dexamethasone: adverse effect of deletion 17p13" Blood (2009) 10.1182/blood-2008-12-193458
[35]
Bataille "Rearrangements of the c-myc oncogene are present in 15% of primary human multiple myeloma tumors" Blood (2001) 10.1182/blood.v98.10.3082
[36]
Kuehl "Diverse karyotypic abnormalities of the c-myc locus associated with c-myc dysregulation and tumor progression in multiple myeloma" Proc Natl Acad Sci U S A (2000) 10.1073/pnas.97.1.228
[37]
Fonseca "Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma" Leukemia (2011) 10.1038/leu.2011.53
[38]
Huber "Expression of the c-myc proto-oncogene in multiple myeloma and chronic lymphocytic leukemia: an in situ analysis" Blood (1991) 10.1182/blood.v78.1.180.180
[39]
Ameglio "c-MYC deregulation is involved in melphalan resistance of multiple myeloma: role of PDGF-BB" Int J Immunopathol Pharmacol (2006)
[40]
Richardson "Treatment options for relapsed and refractory multiple myeloma" Clin Cancer Res (2011) 10.1158/1078-0432.ccr-10-1805
[41]
Greipp "Clinical course of patients with relapsed multiple myeloma" Mayo Clin Proc (2004) 10.4065/79.7.867
[42]
Spencer "MEK inhibitors as a chemotherapeutic intervention in multiple myeloma" Blood Cancer J (2013) 10.1038/bcj.2013.1
[43]
Licht "MEK and MAF in myeloma therapy" Blood (2011) 10.1182/blood-2011-01-327262
[44]
Morgan "A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial" Leukemia (2012) 10.1038/leu.2011.204
[45]
Shaughnessy "Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation" Blood (2006) 10.1182/blood-2006-03-009910
[46]
Inazawa "Overexpression of PDZK1 within the 1q12-q22 amplicon is likely to be associated with drug-resistance phenotype in multiple myeloma" Am J Pathol (2004) 10.1016/s0002-9440(10)63276-2
[47]
Shaughnessy "Amplification and overexpression of CKS1B at chromosome band 1q21 is associated with reduced levels of p27Kip1 and an aggressive clinical course in multiple myeloma" Hematology (2005) 10.1080/10245330512331390140
[48]
Brown "Identification and partial characterization of PDZK1: a novel protein containing PDZ interaction domains" Lab Invest (1998)
[49]
Borst "Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines" Cancer Res (1997)
[50]
Shaughnessy "CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms" Blood (2007) 10.1182/blood-2006-07-038703

Showing 50 of 253 references

Metrics
139
Citations
253
References
Details
Published
Nov 24, 2013
Vol/Issue
4(12)
Pages
2186-2207
Cite This Article
Jahangir Abdi, Guoan Chen, Hong Chang (2013). Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms. Oncotarget, 4(12), 2186-2207. https://doi.org/10.18632/oncotarget.1497
Related

You May Also Like