A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation

Cristina Moncunill-Massaguer; José Saura-Esteller; Alba Pérez-Perarnau; Claudia Mariela Palmeri; Sonia Núñez-Vázquez; Ana M. Cosialls; Diana M. González-Gironès; Helena Pomares; Anne Korwitz; Sara Preciado; Fernando Albericio; Rodolfo Lavilla; Gabriel Pons; Thomas Langer; Daniel Iglesias-Serret; Joan Gil

doi:10.18632/oncotarget.6154

journal article Oct 19, 2015

A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation

Cristina Moncunill-Massaguer José Saura-Esteller Alba Pérez-Perarnau Claudia Mariela Palmeri Sonia Núñez-Vázquez Ana M. Cosialls Diana M. González-Gironès Helena Pomares Anne Korwitz Sara Preciado Fernando Albericio

Rodolfo Lavilla Gabriel Pons Thomas Langer

Daniel Iglesias-Serret Joan Gil

Oncotarget Vol. 6 No. 39 pp. 41750-41765 · Impact Journals, LLC

View at Publisher Save 10.18632/oncotarget.6154

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Published: Oct 19, 2015
Vol/Issue: 6(39)
Pages: 41750-41765

Authors

C

Cristina Moncunill-Massaguer

Departament de Ciències Fisiològiques II, Universitat de Barcelona-Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Catalunya, Spain

J

José Saura-Esteller

Departament de Ciències Fisiològiques II, Universitat de Barcelona-Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Catalunya, Spain

A

Alba Pérez-Perarnau

Departament de Ciències Fisiològiques II, Universitat de Barcelona-Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Catalunya, Spain

C

Claudia Mariela Palmeri

Departament de Ciències Fisiològiques II, Universitat de Barcelona-Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Catalunya, Spain

S

Sonia Núñez-Vázquez

Departament de Ciències Fisiològiques II, Universitat de Barcelona-Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Catalunya, Spain

A

Ana M. Cosialls

Departament de Ciències Fisiològiques II, Universitat de Barcelona-Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Catalunya, Spain

D

Diana M. González-Gironès

Departament de Ciències Fisiològiques II, Universitat de Barcelona-Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Catalunya, Spain

H

Helena Pomares

Departament de Ciències Fisiològiques II, Universitat de Barcelona-Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Catalunya, Spain

A

Anne Korwitz

Institute for Genetics and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany

S

Sara Preciado

Barcelona Science Park and CIBER-BBN, Networking Centre on Bioengineering, Biomaterials and Nanomedicine, Barcelona, Spain

F

Fernando Albericio

Barcelona Science Park and CIBER-BBN, Networking Centre on Bioengineering, Biomaterials and Nanomedicine, Barcelona, Spain; Institute for Research in Biomedicine Barcelona, Barcelona, Spain; Department of Organic Chemistry, University of Barcelona, Barcelona, Spain

R

Rodolfo Lavilla

Barcelona Science Park and CIBER-BBN, Networking Centre on Bioengineering, Biomaterials and Nanomedicine, Barcelona, Spain; Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain

G

Gabriel Pons

Departament de Ciències Fisiològiques II, Universitat de Barcelona-Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Catalunya, Spain

T

Thomas Langer

Institute for Genetics and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany

D

Daniel Iglesias-Serret

Departament de Ciències Fisiològiques II, Universitat de Barcelona-Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Catalunya, Spain

J

Joan Gil

Departament de Ciències Fisiològiques II, Universitat de Barcelona-Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Catalunya, Spain

Cite This Article

Cristina Moncunill-Massaguer, José Saura-Esteller, Alba Pérez-Perarnau, et al. (2015). A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation. Oncotarget, 6(39), 41750-41765. https://doi.org/10.18632/oncotarget.6154

A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation

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