journal article Mar 15, 2016

CCR5 knockout suppresses experimental autoimmune encephalomyelitis in C57BL/6 mice

Oncotarget Vol. 7 No. 13 pp. 15382-15393 · Impact Journals, LLC
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References
76
[1]
Goverman "Mechanisms regulating regional localization of inflammation during CNS autoimmunity" Immunological reviews (2012) 10.1111/j.1600-065x.2012.01126.x
[2]
Gran "Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)" British journal of pharmacology (2011) 10.1111/j.1476-5381.2011.01302.x
[3]
Zipp "Molecular mechanisms linking neuroinflammation and neurodegeneration in MS" Experimental neurology (2014)
[4]
Lane "Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide" Journal of immunology (1993) 10.4049/jimmunol.151.4.2132
[5]
Sedgwick "Unimpaired autoreactive T-cell traffic within the central nervous system during tumor necrosis factor receptor-mediated inhibition of experimental autoimmune encephalomyelitis" Proceedings of the National Academy of Sciences of the United States of America (1995) 10.1073/pnas.92.24.11066
[6]
Johnson "Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system" Neurology (1987) 10.1212/wnl.37.7.1097
[7]
Clark "An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis" The Journal of experimental medicine (1990) 10.1084/jem.172.4.1193
[8]
Feldmann "Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins" European journal of immunology (1994) 10.1002/eji.1830240916
[9]
Sedgwick "Interactions between hemopoietically derived TNF and central nervous system-resident glial chemokines underlie initiation of autoimmune inflammation in the brain" Journal of immunology (2002) 10.4049/jimmunol.169.12.7054
[10]
Sedgwick "Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting" The Journal of experimental medicine (1997) 10.1084/jem.186.9.1585
[11]
Soulika "IFN-gamma signaling in the central nervous system controls the course of experimental autoimmune encephalomyelitis independently of the localization and composition of inflammatory foci" Journal of neuroinflammation (2012)
[12]
Iwakura "Abnormal T cell activation caused by the imbalance of the IL-1/IL-1R antagonist system is responsible for the development of experimental autoimmune encephalomyelitis" International immunology (2006) 10.1093/intimm/dxh379
[13]
Narumi "Interleukin-1beta induces tissue- and cell type-specific expression of adhesion molecules" Arteriosclerosis, thrombosis, and vascular biology (1998) 10.1161/01.atv.18.8.1292
[14]
Karpus "Acute and relapsing experimental autoimmune encephalomyelitis are regulated by differential expression of the CC chemokines macrophage inflammatory protein-1alpha and monocyte chemotactic protein-1" Journal of neuroimmunology (1998) 10.1016/s0165-5728(98)00187-8
[15]
Ruddle "Kinetics and cellular origin of cytokines in the central nervous system: insight into mechanisms of myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis" Journal of immunology (2000) 10.4049/jimmunol.164.1.419
[16]
Ransohoff "Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis" The Journal of experimental medicine (2001) 10.1084/jem.193.6.713
[17]
Karin "Long-lasting protective immunity to experimental autoimmune encephalomyelitis following vaccination with naked DNA encoding C-C chemokines" Journal of immunology (1998) 10.4049/jimmunol.161.8.3870
[18]
Hong "Deficiency of C-C chemokine receptor 5 suppresses tumor developmentinactivation of NF-kappaB and inhibition of monocyte chemoattractant protein-1 in urethane-induced lung tumor model" Carcinogenesis (2012) 10.1093/carcin/bgs265
[19]
Charo "Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice" The Journal of clinical investigation (1997) 10.1172/jci119798
[20]
Bravo "Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor" The Journal of experimental medicine (1997) 10.1084/jem.186.10.1757
[21]
Klein "CXCR7 antagonism prevents axonal injury during experimental autoimmune encephalomyelitis as revealed byaxial diffusivity" Journal of neuroinflammation (2011) 10.1186/1742-2094-8-170
[22]
Dustin "Two-photon laser scanning microscopy imaging of intact spinal cord and cerebral cortex reveals requirement for CXCR6 and neuroinflammation in immune cell infiltration of cortical injury sites" Journal of immunological methods (2010) 10.1016/j.jim.2009.09.007
[23]
Pittaluga "Functional adaptation of presynaptic chemokine receptors in EAE mouse central nervous system" Synapse (2014) 10.1002/syn.21774
[24]
Rostami "IL-9 is important for T-cell activation and differentiation in autoimmune inflammation of the central nervous system" European journal of immunology (2011) 10.1002/eji.201041125
[25]
Rieckmann "Pathogenesis and therapy of multiple sclerosis. The role of cytokines [Article in German]" Der Nervenarzt (1995)
[26]
Mohler "Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery" Journal of immunology (1992) 10.4049/jimmunol.149.7.2496
[27]
Ransohoff "Treatment of experimental autoimmune encephalomyelitis with the chemokine receptor antagonist Met-RANTES" Journal of neuroimmunology (2002) 10.1016/s0165-5728(02)00121-2
[28]
Hancock "Leukocyte recruitment during onset of experimental allergic encephalomyelitis is CCR1 dependent" European journal of immunology (2000) 10.1002/1521-4141(2000)30:8<2372::aid-immu2372>3.0.co;2-d
[29]
Karpus "CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis" The Journal of experimental medicine (2000) 10.1084/jem.192.6.899
[30]
Ransohoff "Myelin repair is accelerated by inactivating CXCR2 on nonhematopoietic cells" The Journal of neuroscience (2010) 10.1523/jneurosci.1238-10.2010
[31]
Kakiuchi "CCR7 ligands are required for development of experimental autoimmune encephalomyelitis through generating IL-23-dependent Th17 cells" Journal of immunology (2009) 10.4049/jimmunol.0800729
[32]
Issekutz "CXCR3 blockade inhibits T-cell migration into the CNS during EAE and prevents development of adoptively transferred, but not actively induced, disease" European journal of immunology (2010) 10.1002/eji.200939975
[33]
Varona "CCR6 regulates EAE pathogenesis by controlling regulatory CD4+ T-cell recruitment to target tissues" European journal of immunology (2009) 10.1002/eji.200839123
[34]
Kunkel "Chemokines in autoimmune disease" Current Opinion in Immunology (2001) 10.1016/s0952-7915(01)00277-1
[35]
Godessart "Chemokines in autoimmunity: from pathology to therapeutics" Autoimmunity Reviews (2002) 10.1016/s1568-9972(02)00085-x
[36]
Salvarani "Relationship between serum RANTES levels and radiological progression in rheumatoid arthritis patients treated with methotrexate" Clinical and experimental rheumatology (1999)
[37]
Whichard "CXCR3 and CCR5 ligands in rheumatoid arthritis synovium" Clinical Immunology (2001) 10.1006/clim.2000.4957
[38]
el-Eissawy "The role of T helper cell subsets in pathogenesis of Systemic Lupus Erythematosus and their relation to disease activity" The Egyptian journal of immunology (2006)
[39]
Owens "Induction of experimental autoimmune encephalomyelitis in C57BL/6 mice deficient in either the chemokine macrophage inflammatory protein-1alpha or its CCR5 receptor" European journal of immunology (2000) 10.1002/(sici)1521-4141(200005)30:5<1410::aid-immu1410>3.0.co;2-l
[40]
Guo "Mimic peptides bonding specifically with the first and second extracellular loops of the CC chemokine receptor 5 derived from a phage display peptide library are potent inhibitors of experimental autoimmune encephalomyelitis" Inflammation research (2011) 10.1007/s00011-011-0331-8
[41]
Ransohoff "Investigating chemokines and chemokine receptors in patients with multiple sclerosis: opportunities and challenges" Archives of neurology (2001) 10.1001/archneur.58.12.1975
[42]
Kollias "Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha" Proceedings of the National Academy of Sciences of the United States of America (1995) 10.1073/pnas.92.24.11294
[43]
Hancock "CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions" Proceedings of the National Academy of Sciences of the United States of America (1999) 10.1073/pnas.96.12.6873
[44]
Near "Protective effect of the interleukin-1 receptor antagonist (IL-1ra) on experimental allergic encephalomyelitis in rats" Journal of neuroimmunology (1995) 10.1016/0165-5728(95)00108-e
[45]
Stosic-Grujicic "Interleukin-1 receptor antagonist suppresses experimental autoimmune encephalomyelitis (EAE) in rats by influencing the activation and proliferation of encephalitogenic cells" Journal of neuroimmunology (1998) 10.1016/s0165-5728(98)00020-4
[46]
Moldawer "The induction of EAE is only partially dependent on TNF receptor signaling but requires the IL-1 type I receptor" Clinical immunology (Orlando, Fla) (2000) 10.1006/clim.2000.4851
[47]
Ransohoff "The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE)" Seminars in immunology (2003) 10.1016/s1044-5323(02)00125-2
[48]
Ransohoff "Synchronous synthesis of alpha- and beta-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encephalomyelitis" The American journal of pathology (1997)
[49]
Brosnan "MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study" Journal of neuroimmunology (1998) 10.1016/s0165-5728(98)00002-2
[50]
Woodroofe "Expression of monocyte chemoattractant protein-1 and other beta-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions" Journal of neuroimmunology (1998) 10.1016/s0165-5728(97)00208-7

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Published
Mar 15, 2016
Vol/Issue
7(13)
Pages
15382-15393
Authors
Cite This Article
Sun Mi Gu, Mi Hee Park, Hyung Mun Yun, et al. (2016). CCR5 knockout suppresses experimental autoimmune encephalomyelitis in C57BL/6 mice. Oncotarget, 7(13), 15382-15393. https://doi.org/10.18632/oncotarget.8097
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