2. Diagnosis and Classification of Diabetes:Standards of Care in Diabetes—2024

The American Diabetes Association (ADA) “Standards of Care in Diabetes” includes the ADA’s current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, an interprofessional expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA’s clinical practice recommendations and a full list of Professional Practice Committee members, please refer to Introduction and Methodology. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.

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References

234

[1]

Sacks "Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus" Diabetes Care (2023) 10.2337/dci23-0036

[2]

American Diabetes Association "Diagnosis and classification of diabetes mellitus" Diabetes Care (2014) 10.2337/dc14-s081

[3]

International Expert Committee "International Expert Committee report on the role of the A1C assay in the diagnosis of diabetes" Diabetes Care (2009) 10.2337/dc09-9033

[4]

Meijnikman "Not performing an OGTT results in significant underdiagnosis of (pre)diabetes in a high risk adult Caucasian population" Int J Obes (2017) 10.1038/ijo.2017.165

[5]

Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

New England Journal of Medicine 2002 10.1056/nejmoa012512

[6]

Tuomilehto "Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance" N Engl J Med (2001) 10.1056/nejm200105033441801

[7]

Diabetes Prevention Program Research Group "HbA1c as a predictor of diabetes and as an outcome in the diabetes prevention program: a randomized clinical trial" Diabetes Care (2015) 10.2337/dc14-0886

[8]

Echouffo-Tcheugui "Prediabetes and what it means: the epidemiological evidence" Annu Rev Public Health (2021) 10.1146/annurev-publhealth-090419-102644

[9]

Chadha "Reproducibility of a prediabetes classification in a contemporary population" Metabol Open (2020) 10.1016/j.metop.2020.100031

[10]

Expert Committee on the Diagnosis and Classification of Diabetes Mellitus "Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus" Diabetes Care (1997) 10.2337/diacare.20.7.1183

[11]

Expert Committee on the Diagnosis and Classification of Diabetes Mellitus "Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus" Diabetes Care (2003) 10.2337/diacare.26.2007.s5

[12]

Klein "Carbohydrate intake prior to oral glucose tolerance testing" J Endocr Soc (2021) 10.1210/jendso/bvab049

[13]

Conn "Interpretation of the glucose tolerance test. The necessity of a standard preparatory diet" Am J Med Sci (1940) 10.1097/00000441-194004000-00014

[14]

Wilkerson "The effect of prior carbohydrate intake on the oral glucose tolerance test" Diabetes (1960) 10.2337/diab.9.5.386

[15]

Lenters-Westra "Six of eight hemoglobin A1c point-of-care instruments do not meet the general accepted analytical performance criteria" Clin Chem (2010) 10.1373/clinchem.2009.130641

[16]

Hirst "Performance of point-of-care HbA1c test devices: implications for use in clinical practice—a systematic review and meta-analysis" Clin Chem Lab Med (2017) 10.1515/cclm-2016-0303

[17]

Nathan "Accuracy of a point-of-care hemoglobin A1c assay" J Diabetes Sci Technol (2019) 10.1177/1932296819836101

[18]

Centers for Medicare & Medicaid Services . CLIA Brochures. Accessed 26 September 2023. Available from https://www.cms.gov/Regulations-and-Guidance/Legislation/CLIA/CLIA_Brochures

[19]

Eckhardt "Glycated hemoglobin A(1c) as screening for diabetes mellitus in HIV-infected individuals" AIDS Patient Care STDS (2012) 10.1089/apc.2011.0379

[20]

Kim "A1C underestimates glycemia in HIV infection" Diabetes Care (2009) 10.2337/dc09-0177

[21]

Wheeler "Impact of common genetic determinants of hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: a transethnic genome-wide meta-analysis" PLoS Med (2017) 10.1371/journal.pmed.1002383

[22]

Bergenstal "Racial differences in the relationship of glucose concentrations and hemoglobin A1c levels" Ann Intern Med (2017) 10.7326/m16-2596

[23]

Herman "Differences in A1C by race and ethnicity among patients with impaired glucose tolerance in the Diabetes Prevention Program" Diabetes Care (2007) 10.2337/dc06-2003

[24]

Saaddine "Distribution of HbA(1c) levels for children and young adults in the U.S.: Third National Health and Nutrition Examination Survey" Diabetes Care (2002) 10.2337/diacare.25.8.1326

[25]

Selvin "Racial differences in glycemic markers: a cross-sectional analysis of community-based data" Ann Intern Med (2011) 10.7326/0003-4819-154-5-201103010-00004

[26]

Landry "Lack of diversity in genomic databases is a barrier to translating precision medicine research into practice" Health Aff (Millwood) (2018) 10.1377/hlthaff.2017.1595

[27]

Wojcik "Genetic analyses of diverse populations improves discovery for complex traits" Nature (2019) 10.1038/s41586-019-1310-4

[28]

Selvin "No racial differences in the association of glycated hemoglobin with kidney disease and cardiovascular outcomes" Diabetes Care (2013) 10.2337/dc12-2715

[29]

Selvin "Prognostic implications of single-sample confirmatory testing for undiagnosed diabetes: a prospective cohort study" Ann Intern Med (2018) 10.7326/m18-0091

[30]

Rewers "Incidence of diabetic ketoacidosis at diagnosis of type 1 diabetes in Colorado youth, 1998-2012" JAMA (2015) 10.1001/jama.2015.1414

[31]

Alonso "Diabetic ketoacidosis at diagnosis of type 1 diabetes in Colorado children, 2010-2017" Diabetes Care (2020) 10.2337/dc19-0428

[32]

Jensen "Increase in prevalence of diabetic ketoacidosis at diagnosis among youth with type 1 diabetes: the SEARCH for Diabetes in Youth Study" Diabetes Care (2021) 10.2337/dc20-0389

[33]

Humphreys "Individual and diabetes presentation characteristics associated with partial remission status in children and adults evaluated up to 12 months following diagnosis of type 1 diabetes: an ADDRESS-2 (After Diagnosis Diabetes Research Support System-2) study analysis" Diabetes Res Clin Pract (2019) 10.1016/j.diabres.2019.107789

[34]

Thomas "Type 1 diabetes defined by severe insulin deficiency occurs after 30 years of age and is commonly treated as type 2 diabetes" Diabetologia (2019) 10.1007/s00125-019-4863-8

[35]

Hope "Practical classification guidelines for diabetes in patients treated with insulin: a cross-sectional study of the accuracy of diabetes diagnosis" Br J Gen Pract (2016) 10.3399/bjgp16x684961

[36]

Holt "The management of type 1 diabetes in adults. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)" Diabetes Care (2021) 10.2337/dci21-0043

[37]

Zhong "Trends in hospital admission for diabetic ketoacidosis in adults with type 1 and type 2 diabetes in England, 1998-2013: a retrospective cohort study" Diabetes Care (2018) 10.2337/dc17-1583

[38]

Lawrence "Incidence and predictors of type 1 diabetes among younger adults aged 20-45 years: the diabetes in young adults (DiYA) study" Diabetes Res Clin Pract (2021) 10.1016/j.diabres.2020.108624

[39]

Vellanki "Diabetic ketoacidosis: a common debut of diabetes among African Americans with type 2 diabetes" Endocr Pract (2017) 10.4158/ep161679.ra

[40]

Skyler "Differentiation of diabetes by pathophysiology, natural history, and prognosis" Diabetes (2017) 10.2337/db16-0806

[41]

Williams "Personalized type 2 diabetes management: an update on recent advances and recommendations" Diabetes Metab Syndr Obes (2022) 10.2147/dmso.s331654

[42]

Seroconversion to Multiple Islet Autoantibodies and Risk of Progression to Diabetes in Children

Anette G. Ziegler, Marian Rewers, Olli Simell et al.

JAMA 2013 10.1001/jama.2013.6285

[43]

Ziegler "Age-related islet autoantibody incidence in offspring of patients with type 1 diabetes" Diabetologia (2012) 10.1007/s00125-012-2472-x

[44]

Parikka "Early seroconversion and rapidly increasing autoantibody concentrations predict prepubertal manifestation of type 1 diabetes in children at genetic risk" Diabetologia (2012) 10.1007/s00125-012-2523-3

[45]

Krischer "The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study" Diabetologia (2015) 10.1007/s00125-015-3514-y

[46]

Bogun "C-peptide levels in subjects followed longitudinally before and after type 1 diabetes diagnosis in TrialNet" Diabetes Care (2020) 10.2337/dc19-2288

[47]

Insel "Staging presymptomatic type 1 diabetes: a scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association" Diabetes Care (2015) 10.2337/dc15-1419

[48]

Zhu "Glutamic acid decarboxylase autoantibody detection by electrochemiluminescence assay identifies latent autoimmune diabetes in adults with poor islet function" Diabetes Metab J (2020) 10.4093/dmj.2019.0007

[49]

Lynam "Development and validation of multivariable clinical diagnostic models to identify type 1 diabetes requiring rapid insulin therapy in adults aged 18-50 years" BMJ Open (2019) 10.1136/bmjopen-2019-031586

[50]

Jones "Latent autoimmune diabetes of adults (LADA) is likely to represent a mixed population of autoimmune (type 1) and nonautoimmune (type 2) diabetes" Diabetes Care (2021) 10.2337/dc20-2834

Showing 50 of 234 references

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Details

Published: Dec 11, 2023
Vol/Issue: 47(Supplement_1)
Pages: S20-S42
License: View

Authors

Raveendhara R. Bannuru

Department of Diabetes Research Centre, University of Leicester, Leicester Diabetes Centre, Leicester General Hospital, Leicester, UK

Cite This Article

Nuha A. ElSayed, Grazia Aleppo, Raveendhara R. Bannuru, et al. (2023). 2. Diagnosis and Classification of Diabetes:Standards of Care in Diabetes—2024. Diabetes Care, 47(Supplement_1), S20-S42. https://doi.org/10.2337/dc24-s002

2. Diagnosis and Classification of Diabetes:Standards of Care in Diabetes—2024

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