Flavonoids: Antioxidant Powerhouses and Their Role in Nanomedicine

Mehak Zahra; Heidi Abrahamse; Blassan P. George

doi:10.3390/antiox13080922

journal article Open Access Jul 29, 2024

Flavonoids: Antioxidant Powerhouses and Their Role in Nanomedicine

Mehak Zahra

Heidi Abrahamse

Blassan P. George

Antioxidants Vol. 13 No. 8 pp. 922 · MDPI AG

View at Publisher Save 10.3390/antiox13080922

Abstract

This study emphasizes the critical role of antioxidants in protecting human health by counteracting the detrimental effects of oxidative stress induced by free radicals. Antioxidants—found in various forms such as vitamins, minerals, and the phytochemicals abundant in fruits and vegetables—neutralize free radicals by stabilizing them through electron donation. Specifically, flavonoid compounds are highlighted as robust defenders, addressing oxidative stress and inflammation to avert chronic illnesses like cancer, cardiovascular diseases, and neurodegenerative diseases. This research explores the bioactive potential of flavonoids, shedding light on their role not only in safeguarding health, but also in managing conditions such as diabetes, cancer, cardiovascular diseases, and neurodegenerative diseases. This review highlights the novel integration of South African-origin flavonoids with nanotechnology, presenting a cutting-edge strategy to improve drug delivery and therapeutic outcomes. This interdisciplinary approach, blending traditional wisdom with contemporary techniques, propels the exploration of flavonoid-mediated nanoparticles toward groundbreaking pharmaceutical applications, promising revolutionary advancements in healthcare. This collaborative synergy between traditional knowledge and modern science not only contributes to human health, but also underscores a significant step toward sustainable and impactful biomedical innovations, aligning with principles of environmental conservation.

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References

Details

Published: Jul 29, 2024
Vol/Issue: 13(8)
Pages: 922
License: View

Authors

M

Mehak Zahra

Laser Research Centre, Faculty of Health Sciences, University of Johannesburg, P.O. Box 1711, Doornfontein 2028, South Africa

H

Heidi Abrahamse

Laser Research Centre, Faculty of Health Sciences, University of Johannesburg, P.O. Box 1711, Doornfontein 2028, South Africa

B

Blassan P. George

Laser Research Centre, Faculty of Health Sciences, University of Johannesburg, P.O. Box 1711, Doornfontein 2028, South Africa

Funding

South African Medical Research Council Award: 98337

University of Johannesburg Award: 98337

University Research Committee (URC) Award: 98337

Council for Scientific Industrial Research (CSIR)-National Laser Centre (NLC) Award: 98337

Cite This Article

Mehak Zahra, Heidi Abrahamse, Blassan P. George (2024). Flavonoids: Antioxidant Powerhouses and Their Role in Nanomedicine. Antioxidants, 13(8), 922. https://doi.org/10.3390/antiox13080922

Flavonoids: Antioxidant Powerhouses and Their Role in Nanomedicine

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