Bioprocess Strategy of Haematococcus lacustris for Biomass and Astaxanthin Production Keys to Commercialization: Perspective and Future Direction

Siti Nur Hazwani Oslan; Siti Nurbaya Oslan; Rosfarizan Mohamad; Joo Shun Tan; Abdul Hafidz Yusoff; Patricia Matanjun; Ruzaidi Azli Mohd Mokhtar; Rossita Shapawi; Nurul Huda

doi:10.3390/fermentation8040179

journal article Open Access Apr 11, 2022

Bioprocess Strategy of Haematococcus lacustris for Biomass and Astaxanthin Production Keys to Commercialization: Perspective and Future Direction

Siti Nur Hazwani Oslan

Patricia Matanjun Ruzaidi Azli Mohd Mokhtar

Rossita Shapawi

Nurul Huda

Fermentation Vol. 8 No. 4 pp. 179 · MDPI AG

View at Publisher Save 10.3390/fermentation8040179

Abstract

Haematococcus lacustris (formerly called Haematococcus pluvialis) is regarded as the most promising microalgae for the production of natural astaxanthin, which is secondary metabolism used as a dietary supplement, also for cosmetic applications, due to its high anti-oxidant activity. Astaxanthin has a wide range of biological activities and high economic potential, and currently dominates the market in its synthetic form. Furthermore, because of the difficulty of bioprocess and the high cost of cultivation, astaxanthin extracted from this microalga is still expensive due to its low biomass and pigment productivities. Large-scale biomass production in biotechnological production necessitates the processing of a large number of cultures as well as the use of both indoor and outdoor systems, such as open pond raceway systems and photo-bioreactors (PBR). The photo-bioreactors systems are suitable for mass production because growth conditions can be controlled, and the risk of contamination can be reduced to a certain extent and under specific culture parameters. This review discusses current technologies being developed to improve cultivation and operation efficiency and profitability, as well as the effect of parameter factors associated with H. lacustris cultivation on biomass and astaxanthin bioproduction, and even strategies for increasing bioproduction and market potential for H. lacustris astaxanthin.

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Details

Published: Apr 11, 2022
Vol/Issue: 8(4)
Pages: 179
License: View

Authors

S

Siti Nur Hazwani Oslan

Faculty of Food Science and Nutrition, Universiti Malaysia Sabah, Jalan UMS, Kota Kinabalu 88400, Sabah, Malaysia

S

Siti Nurbaya Oslan

Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, UPM Serdang, Seri Kembangan 43400, Selangor, Malaysia

R

Rosfarizan Mohamad

Department of Bioprocess Technology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, UPM Serdang, Seri Kembangan 43400, Selangor, Malaysia

J

Joo Shun Tan

Bioprocess Technology, School of Industrial Technology, Universiti Sains Malaysia, Gelugor 11800, Penang, Malaysia

A

Abdul Hafidz Yusoff

Gold Rare Earth and Material Technopreneurship Centre (GREAT), Faculty of Bioengineering and Technology, Universiti Malaysia Kelantan, Jeli Campus, Jeli 17600, Kelantan, Malaysia

P

Patricia Matanjun

Faculty of Food Science and Nutrition, Universiti Malaysia Sabah, Jalan UMS, Kota Kinabalu 88400, Sabah, Malaysia

R

Ruzaidi Azli Mohd Mokhtar

Biotechnology Research Institute, Universiti Malaysia Sabah, Jalan UMS, Kota Kinabalu 88400, Sabah, Malaysia

R

Rossita Shapawi

Borneo Marine Research Institute, Universiti Malaysia Sabah, Jalan UMS, Kota Kinabalu 88400, Sabah, Malaysia

N

Nurul Huda

Faculty of Food Science and Nutrition, Universiti Malaysia Sabah, Jalan UMS, Kota Kinabalu 88400, Sabah, Malaysia

Cite This Article

Siti Nur Hazwani Oslan, Siti Nurbaya Oslan, Rosfarizan Mohamad, et al. (2022). Bioprocess Strategy of Haematococcus lacustris for Biomass and Astaxanthin Production Keys to Commercialization: Perspective and Future Direction. Fermentation, 8(4), 179. https://doi.org/10.3390/fermentation8040179

Bioprocess Strategy of Haematococcus lacustris for Biomass and Astaxanthin Production Keys to Commercialization: Perspective and Future Direction

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