Streptococcus mutans, Caries and Simulation Models

Sofia D. Forssten; Marika Björklund; Arthur C. Ouwehand

doi:10.3390/nu2030290

journal article Open Access Mar 02, 2010

Streptococcus mutans, Caries and Simulation Models

Sofia D. Forssten Marika Björklund Arthur C. Ouwehand

Nutrients Vol. 2 No. 3 pp. 290-298 · MDPI AG

View at Publisher Save 10.3390/nu2030290

Abstract

Dental caries and dental plaque are among the most common diseases worldwide, and are caused by a mixture of microorganisms and food debris. Specific types of acid-producing bacteria, especially Streptococcus mutans, colonize the dental surface and cause damage to the hard tooth structure in the presence of fermentable carbohydrates e.g., sucrose and fructose. This paper reviews the link between S. mutans and caries, as well as different simulation models that are available for studying caries. These models offer a valuable approach to study cariogenicity of different substrates as well as colonization of S. mutans.

Topics

No keywords indexed for this article. Browse by subject →

References

42

[1]

Marsh "Are dental diseases examples of ecological catastrophes?" Microbiology-Sgm. (2003) 10.1099/mic.0.26082-0

[2]

Aas "Defining the Normal Bacterial Flora of the Oral Cavity" J. Clin. Microbiol. (2005) 10.1128/jcm.43.11.5721-5732.2005

[3]

Sakamoto "Molecular analysis of human oral microbiota" J. Periodont. Res. (2005) 10.1111/j.1600-0765.2005.00793.x

[4]

Holt, J., Krieg, N., Sneath, P., Staley, J., and Williams, S. (1994). Bergey's manual of determinative bacteriology, Williams & Wilkins. [9th].

[5]

Microbial Biofilms: from Ecology to Molecular Genetics

Mary Ellen Davey, George A. O'Toole

Microbiology and Molecular Biology Reviews 2000 10.1128/mmbr.64.4.847-867.2000

[6]

Lamont "Salivary-Agglutinin-Mediated Adherence of Streptococcus-Mutans to Early Plaque Bacteria" Infect. Immun. (1991) 10.1128/iai.59.10.3446-3450.1991

[7]

Marsh "Dental plaque as a biofilm and a microbial community - implications for health and disease" BMC Oral Health (2006) 10.1186/1472-6831-6-s1-s14

[8]

Trahan "Transport and phosphorylation of xylitol by a fructose phosphotransferase system in Streptococcus mutans" Caries Res. (1985) 10.1159/000260829

[9]

Sheiham "Changing Trends in Dental Caries" Int. J. Epidemiol. (1984) 10.1093/ije/13.2.142

[10]

(1990). Dental-Caries in Developed and Developing-Countries. Caries Res., 24, 43. 10.1159/000261324

[11]

Loesche "Role of Streptococcus mutans in human dental decay" Microbiol. Mol. Biol. Rev. (1986)

[12]

Trahan "Xylitol: a review of its action on mutans streptococci and dental plaque--its clinical significance" Int. Dent. J. (1995)

[13]

Desoet "Prevalence of Streptococcus-Sobrinus in Relation to Dental-Caries in Children from Iceland and the Netherlands" J. Dent. Child. (1990)

[14]

Tanzer "The microbiology of primary dental caries in humans" J. Dent. Educ. (2001) 10.1002/j.0022-0337.2001.65.10.tb03446.x

[15]

Mayooran "Dental caries is a preventable infectious disease" Aust. Dent. J. (2000) 10.1111/j.1834-7819.2000.tb00257.x

[16]

Zero "Sugars - The arch criminal?" Caries Res. (2004) 10.1159/000077767

[17]

Wiater "Insoluble glucans synthesized by cariogenic streptococci: a structural study" J. Basic Microbiol. (1999) 10.1002/(sici)1521-4028(199909)39:4<265::aid-jobm265>3.0.co;2-0

[18]

Zisu "Effects of pH, temperature, supplementation with whey protein concentrate, and adjunct cultures on the production of exopolysaccharides by Streptococcus thermophilus 1275" J. Dairy Sci. (2003) 10.3168/jds.s0022-0302(03)73944-7

[19]

Monsan "Homopolysaccharides from lactic acid bacteria" Int. Dairy J. (2001) 10.1016/s0958-6946(01)00113-3

[20]

Toda "Ultrastructure of Extracellular Polysaccharides Produced by Serotype c Streptococcus mutans" J. Dent. Res. (1987) 10.1177/00220345870660081601

[21]

Shellis "Analysis of the Buffering Systems in Dental Plaque" J. Dent. Res. (1988) 10.1177/00220345880670020101

[22]

Hata "Acid diffusion through extracellular polysaccharides produced by various mutants of Streptococcus mutans" Arch. Oral Biol. (2003) 10.1016/s0003-9969(03)00032-3

[23]

Wunder "Effects of antibodies to glucosyltransferase on soluble and insolubilized enzymes" Oral Dis. (2000) 10.1111/j.1601-0825.2000.tb00141.x

[24]

Marsh "Microbiological effects of new agents in dentifrices for plaque control" Int. Dent. J. (1993)

[25]

Rogers "Effects of Pulsing with Xylitol on Mixed Continuous Cultures of Oral Streptococci" Aust. Dent. J. (1991) 10.1111/j.1834-7819.1991.tb04709.x

[26]

Bradshaw "Effect of Sugar Alcohols on the Composition and Metabolism of A Mixed Culture of Oral Bacteria Grown in A Chemostat" Caries Res. (1994) 10.1159/000261977

[27]

Soderling "Xylitol, Mutans Streptococci, and Dental Plaque" Adv. Dental Res. (2009) 10.1177/0895937409335642

[28]

Lee "Xylitol for Prevention of Dental-Caries" Ann. Pharmacother. (1989)

[29]

Macdonald "The Role of Xylitol in the Prevention of Dental-Caries" J. Can. Diet. Assoc. (1988)

[30]

Peldyak "Xylitol for caries prevention" J. Dent. Hyg. (2002)

[31]

Soderling "Effect of Xylitol and Sorbitol on Polysaccharide Production by and Adhesive Properties of Streptococcus-Mutans" Caries Res. (1987) 10.1159/000261011

[32]

Buijs "The effect of triclosan toothpaste on enamel demineralization in a bacterial demineralization model" J. Antimicrob. Chemother. (2000) 10.1093/jac/45.2.153

[33]

DeVizio "Effect of a triclosan/copolymer/fluoride dentifrice on plaque formation and gingivitis: a 7-month clinical study" Am. J. Dent. (1990)

[34]

Phan "Triclosan inhibition of membrane enzymes and glycolysis of Streptococcus mutans in suspensions and biofilms" Can. J. Microbiol. (2006) 10.1139/w06-055

[35]

Haukioja "Oral adhesion and survival of probiotic and other lactobacilli and bifidobacteria in vitro" Oral Microbiol. Immunol. (2006) 10.1111/j.1399-302x.2006.00299.x

[36]

Guggenheim "Validation of an in vitro biofilm model of supragingival plaque" J. Dent. Res. (2001) 10.1177/00220345010800011201

[37]

Herles "Chemostat flow cell system: an in vitro model for the evaluation of antiplaque agents" J. Dent. Res. (1994) 10.1177/00220345940730111101

[38]

Seemann "A novel in vitro microbial-based model for studying caries formation - Development and initial testing" Caries Res. (2005) 10.1159/000084796

[39]

Sissons "A Multi-Station Dental Plaque Microcosm (Artificial Mouth) for the Study of Plaque Growth, Metabolism, Ph, and Mineralization" J. Dent. Res. (1991) 10.1177/00220345910700110301

[40]

Guessous "An animal model for the assessment of gingival lesions" J. Pharmacol. Toxicol. Methods (1994) 10.1016/1056-8719(94)90070-1

[41]

"Animal Caries Models: Reaction Paper" Adv. Dental Res. (1995) 10.1177/08959374950090030401

[42]

White "The Comparative Sensitivity of Intraoral, Invitro, and Animal-Models in the Profile Evaluation of Topical Fluorides" J. Dent. Res. (1992) 10.1177/002203459207100s19

Cited By

341

Streptococcus mutans biofilms in the establishment of dental caries: a review

Thangavelu Thayumanavan, B. S. Harish · 2025

3 Biotech

The Evolving Microbiome of Dental Caries

Grace Spatafora, Yihong Li · 2024

Microorganisms

Antimicrobial Effects of Edible Mixed Herbal Extracts on Oral Microorganisms: An In Vitro Study

Se-Eun Yun, Byul-Bo ra Choi · 2023

Medicina

Effect of Commonly Prescribed Liquid Medications on Streptococcus mutans Biofilm. An in vitro study

Samantha A Clark, LaQuia A Vinson · 2017

Journal of Clinical Pediatric Denti...

Metrics

341

Citations

42

References

Details

Published: Mar 02, 2010
Vol/Issue: 2(3)
Pages: 290-298
License: View

Authors

S

Sofia D. Forssten

Danisco Finland, Sokeritehtaantie 20, 02460 Kantvik, Finland

M

Marika Björklund

Danisco Finland, Sokeritehtaantie 20, 02460 Kantvik, Finland

A

Arthur C. Ouwehand

Danisco Finland, Sokeritehtaantie 20, 02460 Kantvik, Finland

Cite This Article

Sofia D. Forssten, Marika Björklund, Arthur C. Ouwehand (2010). Streptococcus mutans, Caries and Simulation Models. Nutrients, 2(3), 290-298. https://doi.org/10.3390/nu2030290

Streptococcus mutans, Caries and Simulation Models

You May Also Like