journal article
Open Access
Jul 27, 2016
The Effect of Casein Protein Prior to Sleep on Fat Metabolism in Obese Men
Abstract
We have previously shown that ingesting protein at night before sleep is either beneficial or non-detrimental to metabolism, health, and body composition in obese women. However, the overnight protein-induced lipolytic actions and mechanism for improved metabolism and body composition have not been fully established. Therefore, in a crossover design, twelve obese men (age, 27.0 ± 2.2 years) were randomly assigned to ingest (within 30 min of sleep) casein protein (CAS, 120 kcal) or a non-nutritive placebo (PLA) before going to sleep. Markers of fat metabolism (lipolysis, substrate utilization, growth hormone), insulin, glucose, resting energy expenditure (REE), and appetite (questionnaire and ghrelin) were measured. During sleep and the next morning, interstitial glycerol from the subcutaneous abdominal adipose tissue (SCAAT) was measured using microdialysis. There were no differences in SCAAT glycerol (overnight: CAS, 177.4 ± 26.7; PLA, 183.8 ± 20.2 μmol/L; morning: CAS, 171.6 ± 19.1; PLA, 161.5 ± 18.6 μmol/L), substrate utilization, REE, or any blood markers between CAS and PLA. Desire to eat was greater for CAS compared to baseline (p = 0.03), but not different from PLA (baseline: 39 ± 6, CAS: 62 ± 8, PLA: 55 ± 5 mm). CAS consumption before sleep did not affect fat or glucose metabolism, REE, or suppress appetite in hyperinsulemic obese men. CAS may be consumed before sleep without impeding overnight or morning fat metabolism in young, obese men.
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Adipose Lipolysis Unchanged by Preexercise Carbohydrate Regardless of Glycemic Index
Medicine & Science in Sports &a...
DANIEL A. BAUR, BRANDON D. WILLINGHAM · 2018
Metrics
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Citations
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References
Details
- Published
- Jul 27, 2016
- Vol/Issue
- 8(8)
- Pages
- 452
- License
- View
Authors
Funding
NIH
Award: T32DK062710
Dymatize® Nutrition
FSU College of Human Sciences
FSU Graduate School
Cite This Article
Amber Kinsey, Stacy Cappadona, Lynn Panton, et al. (2016). The Effect of Casein Protein Prior to Sleep on Fat Metabolism in Obese Men. Nutrients, 8(8), 452. https://doi.org/10.3390/nu8080452
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