journal article Open Access Aug 16, 2017

Detection Methodologies for Pathogen and Toxins: A Review

Sensors Vol. 17 No. 8 pp. 1885 · MDPI AG
View at Publisher Save 10.3390/s17081885
Abstract
Pathogen and toxin-contaminated foods and beverages are a major source of illnesses, even death, and have a significant economic impact worldwide. Human health is always under a potential threat, including from biological warfare, due to these dangerous pathogens. The agricultural and food production chain consists of many steps such as harvesting, handling, processing, packaging, storage, distribution, preparation, and consumption. Each step is susceptible to threats of environmental contamination or failure to safeguard the processes. The production process can be controlled in the food and agricultural sector, where smart sensors can play a major role, ensuring greater food quality and safety by low cost, fast, reliable, and profitable methods of detection. Techniques for the detection of pathogens and toxins may vary in cost, size, and specificity, speed of response, sensitivity, and precision. Smart sensors can detect, analyse and quantify at molecular levels contents of different biological origin and ensure quality of foods against spiking with pesticides, fertilizers, dioxin, modified organisms, anti-nutrients, allergens, drugs and so on. This paper reviews different methodologies to detect pathogens and toxins in foods and beverages.
Topics

No keywords indexed for this article. Browse by subject →

References
151
[1]
Dwivedi "Detection of pathogens in foods: The current state-of-the-art and future directions" Crit. Rev. Microbiol. (2011) 10.3109/1040841x.2010.506430
[2]
Sayad "A microfluidic lab-on-a-disc integrated loop mediated isothermal amplification for foodborne pathogen detection" Sens. Actuators B Chem. (2016) 10.1016/j.snb.2015.10.116
[3]
Oliver "Foodborne pathogens in milk and the dairy farm environment: Food safety and public health implications" Foodbourne Pathog. Dis. (2005) 10.1089/fpd.2005.2.115
[4]
Services, U.S.D.O.H.H. (2017, August 14). Cdc: Estimates of Foodborne Illness in the United States, Available online: https://www.cdc.gov/foodborneburden/2011-foodborne-estimates.html.
[5]
On, S., Lim, E., Lopez, L., Cressey, P., and Pirie, R. (2011). Annual Report Concerning Foodborne Disease in New Zealand, Enviromental Science and Research Limited (ESR).
[6]
Organization, W.H. (2017, August 14). Foodborne Diseases. Available online: http://www.who.int/foodsafety/areas_work/foodborne-diseases/en/.
[7]
Kirk, M.D., Pires, S.M., Black, R.E., Caipo, M., Crump, J.A., Devleesschauwer, B., Döpfer, D., Fazil, A., Fischer-Walker, C.L., and Hald, T. (2015). World health organization estimates of the global and regional disease burden of 22 foodborne bacterial, protozoal, and viral diseases, 2010: A data synthesis. PLoS Med., 12. 10.1371/journal.pmed.1001940
[8]
Scallan "Foodborne illness acquired in the united states-major pathogens" Emerg. Infect. Dis. (2011) 10.3201/eid1701.p11101
[9]
Butler "Expert elicitation as a means to attribute 28 enteric pathogens to foodborne, waterborne, animal contact, and person-to-person transmission routes in canada" Foodborne Pathog. Dis. (2015) 10.1089/fpd.2014.1856
[10]
Kirk, M., Glass, K., Ford, L., Brown, K., and Hall, G. (2005). Foodborne Illness in Australia: Annual Incidence Circa 2000.
[11]
Vally "Proportion of illness acquired by foodborne transmission for nine enteric pathogens in australia: An expert elicitation" Foodborne Pathog. Dis. (2014) 10.1089/fpd.2014.1746
[12]
Adak "Trends in indigenous foodborne disease and deaths, england and wales: 1992 to 2000" Gut (2002) 10.1136/gut.51.6.832
[13]
Havelaar "Attribution of foodborne pathogens using structured expert elicitation" Foodborne Pathog. Dis. (2008) 10.1089/fpd.2008.0115
[14]
Alocilja "Market analysis of biosensor for food safety" Biosens. Bioelectron. (2003) 10.1016/s0956-5663(03)00009-5
[15]
Wagner, A.B. (2017, August 14). Bacterial Food Poisoning. Available online: http://aggie-horticulture.tamu.edu/food-technology/bacterial-food-poisoning/.
[16]
Seydel "Chemical structure, molecular conformation, and bioactivity of endotoxins" Chem. Immunol. (2000)
[17]
Lazcka "Pathogen detection: A perspective of traditional methods and biosensors" Biosens. Bioelectron. (2007) 10.1016/j.bios.2006.06.036
[18]
Wolff "Improved detection of respiratory pathogens by use of high-quality sputum with taqman array card technology" J. Clin. Microbiol. (2017) 10.1128/jcm.01805-16
[19]
Chen "A self-contained microfluidic in-gel loop-mediated isothermal amplification for multiplexed pathogen detection" Sens. Actuators B Chem. (2017) 10.1016/j.snb.2016.07.164
[20]
Velusamy "An overview of foodborne pathogen detection: In the perspective of biosensors" Biotechnol. Adv. (2010) 10.1016/j.biotechadv.2009.12.004
[21]
Leonard "Advances in biosensors for detection of pathogens in food and water" Enzyme Microb. Technol. (2003) 10.1016/s0141-0229(02)00232-6
[22]
Lee "Review of salmonella detection and identification methods: Aspects of rapid emergency response and food safety" Food Control (2015) 10.1016/j.foodcont.2014.07.011
[23]
Leoni "Comparison of selective procedures for isolation and enumeration of legionella species from hot water systems" J. Appl. Microbiol. (2001) 10.1046/j.1365-2672.2001.01178.x
[24]
Ratnam "Characterization of Escherichia coli serotype 0157:H7" J. Clin. Microbiol. (1988) 10.1128/jcm.26.10.2006-2012.1988
[25]
Fratamico "Comparison of culture, polymerase chain reaction (PCR), taqman salmonella, and transia card salmonella assays for detection of salmonella spp. in naturally-contaminated ground chicken, ground turkey, and ground beef" Mol. Cell. Probes (2003) 10.1016/s0890-8508(03)00056-2
[26]
Oh "Centrifugal loop-mediated isothermal amplification microdevice for rapid, multiplex and colorimetric foodborne pathogen detection" Biosens. Bioelectron. (2016) 10.1016/j.bios.2015.08.052
[27]
Jensen "Rapid identification of bacteria on the basis of polymerase chain reaction-amplified ribosomal DNA spacer polymorphisms" Appl. Environ. Microbiol. (1993) 10.1128/aem.59.4.945-952.1993
[28]
Belgrader "Infectious disease—PCR detection of bacteria in seven minutes" Science (1999) 10.1126/science.284.5413.449
[29]
Naravaneni "Rapid detection of food-borne pathogens by using molecular techniques" J. Med. Microbiol. (2005) 10.1099/jmm.0.45687-0
[30]
Russell "Application of a multiplex PCR for the detection of protozoan pathogens of the eastern oyster crassostrea virginica in field samples" Dis. Aquat. Org. (2004) 10.3354/dao059085
[31]
Lee "Multiplex PCR detection of waterborne intestinal protozoa: Microsporidia, cyclospora, and cryptosporidium" Korean J. Parasitol. (2010) 10.3347/kjp.2010.48.4.297
[32]
Traore "Reverse transcriptase PCR detection of astrovirus, hepatitis a virus, and poliovirus in experimentally contaminated mussels: Comparison of several extraction and concentration methods" Appl. Environ. Microbiol. (1998) 10.1128/aem.64.8.3118-3122.1998
[33]
Wolffs "Simultaneous separation and detection of hepatitis a virus and norovirus in produce" Int. J. Food Microbiol. (2010) 10.1016/j.ijfoodmicro.2010.02.011
[34]
Yaron "A reverse transcriptase-polymerase chain reaction assay for detection of viable Escherichia coli O157: H7: Investigation of specific target genes" J. Appl. Microbiol. (2002) 10.1046/j.1365-2672.2002.01563.x
[35]
Choi "Development of reverse transcriptase-polymerase chain reaction of fima gene to detect viable salmonella in milk" J. Anim. Sci. Technol. (2004) 10.5187/jast.2004.46.5.841
[36]
Lambertz "Real-time PCR method for detection of pathogenic yersinia enterocolitica in food" Appl. Environ. Microbiol. (2008) 10.1128/aem.00405-08
[37]
Mukhopadhyay "Novel multiplex PCR approaches for the simultaneous detection of human pathogens: Escherichia coli O157: H7 and listeria monocytogenes" J. Microbiol. Methods (2007) 10.1016/j.mimet.2006.07.009
[38]
Iqbal "A review of molecular recognition technologies for detection of biological threat agents" Biosens. Bioelectron. (2000) 10.1016/s0956-5663(00)00108-1
[39]
Gracias "A review of conventional detection and enumeration methods for pathogenic bacteria in food" Can. J. Microbiol. (2004) 10.1139/w04-080
[40]
Chen "Simultaneous detection of Escherichia coli O157: H7, salmonella spp. And listeria monocytogenes with an array-based immunosorbent assay using universal protein g-liposomal nanovesicles" Talanta (2006) 10.1016/j.talanta.2005.09.036
[41]
Magliulo "A rapid multiplexed chemiluminescent immunoassay for the detection of Escherichia coli O157: H7, yersinia enterocolitica, salmonella typhimurium, and listeria monocytogenes pathogen bacteria" J. Agric. Food Chem. (2007) 10.1021/jf063600b
[42]
Qadri "Sandwich enzyme immunoassays for detection of salmonella-typhi" J. Immunoass. (1990) 10.1080/01971529008053272
[43]
Chapman "Use of commercial enzyme immunoassays and immunomagnetic separation systems for detecting Escherichia coli O157 in bovine fecal samples" Appl. Environ. Microbiol. (1997) 10.1128/aem.63.7.2549-2553.1997
[44]
Rozand "Specificity analysis of a novel phage-derived ligand in an enzyme-linked fluorescent assay for the detection of Escherichia coli O157: H7" J. Food Protect. (2009) 10.4315/0362-028x-72.5.1078
[45]
Tufi "Detection of Escherichia coli O157 in raw and cooked meat: Comparison of conventional direct culture method and enzyme linked fluorescent assay (ELFA)" Ital. J. Public Health (2011)
[46]
Vazquez "Development and evaluation of an ELISA to detect Escherichia coli K88 (F4) fimbrial antibody levels" J. Med. Microbiol. (1996) 10.1099/00222615-44-6-453
[47]
Song "Development of a lateral flow colloidal gold immunoassay strip for the simultaneous detection of shigella boydii and Escherichia coli O157: H7 in bread, milk and jelly samples" Food Control (2016) 10.1016/j.foodcont.2015.06.012
[48]
Ivnitski "Highly sensitive flow-injection immunoassay system for rapid detection of bacteria" Anal. Chim. Acta (1999) 10.1016/s0003-2670(99)00580-2
[49]
Desruisseau "Evaluation of a 24-h bioluminescent enzyme immunoassay for the rapid detection of salmonella in chicken carcass rinses" J. Food Protect. (2003) 10.4315/0362-028x-66.11.1996
[50]
Rasooly "Detection and analysis of staphylococcal enterotoxin a in food by western immunoblotting" Int. J. Food Microbiol. (1998) 10.1016/s0168-1605(98)00050-6

Showing 50 of 151 references

Cited By
171
Rendiconti Lincei. Scienze Fisiche...
Environment International
Metrics
171
Citations
151
References
Details
Published
Aug 16, 2017
Vol/Issue
17(8)
Pages
1885
License
View
Cite This Article
Md Alahi, Subhas Mukhopadhyay (2017). Detection Methodologies for Pathogen and Toxins: A Review. Sensors, 17(8), 1885. https://doi.org/10.3390/s17081885
Related

You May Also Like

SECOND: Sparsely Embedded Convolutional Detection

Yan Yan, Yuyin Mao · 2018

2,824 citations

Metal Oxide Gas Sensors: Sensitivity and Influencing Factors

Chengxiang Wang, Longwei Yin · 2010

2,595 citations

Machine Learning in Agriculture: A Review

Konstantinos Liakos, Patrizia Busato · 2018

2,472 citations

Wearable Electronics and Smart Textiles: A Critical Review

Matteo Stoppa, Alessandro Chiolerio · 2014

1,823 citations