Non-Invasive Electrochemical Biosensors Operating in Human Physiological Fluids

Magnus Falk; Carolin Psotta; Stefan Cirovic; Sergey Shleev

doi:10.3390/s20216352

journal article Open Access Nov 07, 2020

Non-Invasive Electrochemical Biosensors Operating in Human Physiological Fluids

Magnus Falk Carolin Psotta Stefan Cirovic Sergey Shleev

Sensors Vol. 20 No. 21 pp. 6352 · MDPI AG

View at Publisher Save 10.3390/s20216352

Abstract

Non-invasive healthcare technologies are an important part of research and development nowadays due to the low cost and convenience offered to both healthcare receivers and providers. This work overviews the recent advances in the field of non-invasive electrochemical biosensors operating in secreted human physiological fluids, viz. tears, sweat, saliva, and urine. Described electrochemical devices are based on different electrochemical techniques, viz. amperometry, coulometry, cyclic voltammetry, and impedance spectroscopy. Challenges that confront researchers in this exciting area and key requirements for biodevices are discussed. It is concluded that the field of non-invasive sensing of biomarkers in bodily fluid is highly convoluted. Nonetheless, if the drawbacks are appropriately addressed, and the pitfalls are adroitly circumvented, the approach will most certainly disrupt current clinical and self-monitoring practices.

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Details

Published: Nov 07, 2020
Vol/Issue: 20(21)
Pages: 6352
License: View

Authors

M

Magnus Falk

Department of Biomedical Science, Faculty of Health and Society, and Biofilms—Research Center for Biointerfaces, Malmö University, 20506 Malmö, Sweden

C

Carolin Psotta

Department of Biomedical Science, Faculty of Health and Society, and Biofilms—Research Center for Biointerfaces, Malmö University, 20506 Malmö, Sweden; Aptusens AB, 293 94 Kyrkhult, Sweden

S

Stefan Cirovic

Department of Biomedical Science, Faculty of Health and Society, and Biofilms—Research Center for Biointerfaces, Malmö University, 20506 Malmö, Sweden

S

Sergey Shleev

Department of Biomedical Science, Faculty of Health and Society, and Biofilms—Research Center for Biointerfaces, Malmö University, 20506 Malmö, Sweden; Aptusens AB, 293 94 Kyrkhult, Sweden

Funding

Swedish Knowledge Foundation Award: 2170168

Cite This Article

Magnus Falk, Carolin Psotta, Stefan Cirovic, et al. (2020). Non-Invasive Electrochemical Biosensors Operating in Human Physiological Fluids. Sensors, 20(21), 6352. https://doi.org/10.3390/s20216352

Non-Invasive Electrochemical Biosensors Operating in Human Physiological Fluids

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