Electrocortical Dynamics of Usual Walking and the Planning to Step over Obstacles in Parkinson’s Disease

Rodrigo Vitorio; Ellen Lirani-Silva; Diego Orcioli-Silva; Victor Spiandor Beretta; Anderson Souza Oliveira; Lilian Teresa Bucken Gobbi

doi:10.3390/s23104866

journal article Open Access May 18, 2023

Electrocortical Dynamics of Usual Walking and the Planning to Step over Obstacles in Parkinson’s Disease

Rodrigo Vitorio

Ellen Lirani-Silva

Diego Orcioli-Silva

Victor Spiandor Beretta

Anderson Souza Oliveira

Lilian Teresa Bucken Gobbi

Sensors Vol. 23 No. 10 pp. 4866 · MDPI AG

View at Publisher Save 10.3390/s23104866

Abstract

The neural correlates of locomotion impairments observed in people with Parkinson’s disease (PD) are not fully understood. We investigated whether people with PD present distinct brain electrocortical activity during usual walking and the approach phase of obstacle avoidance when compared to healthy individuals. Fifteen people with PD and fourteen older adults walked overground in two conditions: usual walking and obstacle crossing. Scalp electroencephalography (EEG) was recorded using a mobile 64-channel EEG system. Independent components were clustered using a k-means clustering algorithm. Outcome measures included absolute power in several frequency bands and alpha/beta ratio. During the usual walk, people with PD presented a greater alpha/beta ratio in the left sensorimotor cortex than healthy individuals. While approaching obstacles, both groups reduced alpha and beta power in the premotor and right sensorimotor cortices (balance demand) and increased gamma power in the primary visual cortex (visual demand). Only people with PD reduced alpha power and alpha/beta ratio in the left sensorimotor cortex when approaching obstacles. These findings suggest that PD affects the cortical control of usual walking, leading to a greater proportion of low-frequency (alpha) neuronal firing in the sensorimotor cortex. Moreover, the planning for obstacle avoidance changes the electrocortical dynamics associated with increased balance and visual demands. People with PD rely on increased sensorimotor integration to modulate locomotion.

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References

Details

Published: May 18, 2023
Vol/Issue: 23(10)
Pages: 4866
License: View

Authors

R

Rodrigo Vitorio

Institute of Biosciences, Sao Paulo State University (UNESP), Rio Claro 13506-900, Brazil; Graduate Program in Movement Sciences, São Paulo State University (UNESP), Rio Claro 13506-900, Brazil; Department of Sport, Exercise and Rehabilitation, Northumbria University, Newcastle upon Tyne NE1 8ST, UK

E

Ellen Lirani-Silva

Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK

D

Diego Orcioli-Silva

Institute of Biosciences, Sao Paulo State University (UNESP), Rio Claro 13506-900, Brazil; Graduate Program in Movement Sciences, São Paulo State University (UNESP), Rio Claro 13506-900, Brazil

V

Victor Spiandor Beretta

Institute of Biosciences, Sao Paulo State University (UNESP), Rio Claro 13506-900, Brazil; Graduate Program in Movement Sciences, São Paulo State University (UNESP), Rio Claro 13506-900, Brazil; School of Technology and Sciences, Sao Paulo State University (UNESP), Presidente Prudente 19060-900, Brazil

A

Anderson Souza Oliveira

Department of Materials and Production, Aalborg University, 9220 Aalborg, Denmark

L

Lilian Teresa Bucken Gobbi

Institute of Biosciences, Sao Paulo State University (UNESP), Rio Claro 13506-900, Brazil; Graduate Program in Movement Sciences, São Paulo State University (UNESP), Rio Claro 13506-900, Brazil

Funding

Sao Paulo Research Foundation Award: 2014/22308-0

Coordenaçaõ de Aperfeiçoamento de Pessoal de Nível Superior—Brasil Award: 2014/22308-0

Cite This Article

Rodrigo Vitorio, Ellen Lirani-Silva, Diego Orcioli-Silva, et al. (2023). Electrocortical Dynamics of Usual Walking and the Planning to Step over Obstacles in Parkinson’s Disease. Sensors, 23(10), 4866. https://doi.org/10.3390/s23104866

Electrocortical Dynamics of Usual Walking and the Planning to Step over Obstacles in Parkinson’s Disease

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