Staphylococcus aureus Toxins and Their Molecular Activity in Infectious Diseases

Diana Oliveira; Anabela Borges; Manuel Simões

doi:10.3390/toxins10060252

journal article Open Access Jun 19, 2018

Staphylococcus aureus Toxins and Their Molecular Activity in Infectious Diseases

Diana Oliveira

Anabela Borges

Manuel Simões

Toxins Vol. 10 No. 6 pp. 252 · MDPI AG

View at Publisher Save 10.3390/toxins10060252

Abstract

Staphylococcus aureus is a microorganism resident in the skin and nasal membranes with a dreadful pathogenic potential to cause a variety of community and hospital-acquired infections. The frequency of these infections is increasing and their treatment is becoming more difficult. The ability of S. aureus to form biofilms and the emergence of multidrug-resistant strains are the main reasons determining the challenge in dealing with these infections. S. aureus' infectious capacity and its success as a pathogen is related to the expression of virulence factors, among which the production of a wide variety of toxins is highlighted. For this reason, a better understanding of S. aureus toxins is needed to enable the development of new strategies to reduce their production and consequently improve therapeutic approaches. This review focuses on understanding the toxin-based pathogenesis of S. aureus and their role on infectious diseases.

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References

Details

Published: Jun 19, 2018
Vol/Issue: 10(6)
Pages: 252
License: View

Authors

D

Diana Oliveira

LEPABE, Department of Chemical Engineering, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, s/n, 4200-465 Porto, Portugal

A

Anabela Borges

LEPABE, Department of Chemical Engineering, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, s/n, 4200-465 Porto, Portugal

M

Manuel Simões

LEPABE, Department of Chemical Engineering, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, s/n, 4200-465 Porto, Portugal

Funding

Fundação para a Ciência e a Tecnologia Award: POCI-01-0145-FEDER-006939

Cite This Article

Diana Oliveira, Anabela Borges, Manuel Simões (2018). Staphylococcus aureus Toxins and Their Molecular Activity in Infectious Diseases. Toxins, 10(6), 252. https://doi.org/10.3390/toxins10060252

Staphylococcus aureus Toxins and Their Molecular Activity in Infectious Diseases

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