Comparison of Intravenous Ondansetron and Dexamethasone for Preventing Propofol-Induced Pain During Laparoscopic Cholecystectomy: A Double-Blind, Randomized Study

Aravind Aditya; Khushboo Pandey; Manisha Bhagat; Wasimul Hoda; Priyanka Oraon; Ladhu Lakra

doi:10.7759/cureus.67382

journal article Aug 21, 2024

Comparison of Intravenous Ondansetron and Dexamethasone for Preventing Propofol-Induced Pain During Laparoscopic Cholecystectomy: A Double-Blind, Randomized Study

Aravind Aditya Khushboo Pandey

Manisha Bhagat Wasimul Hoda

Priyanka Oraon Ladhu Lakra

Cureus · Springer Science and Business Media LLC

View at Publisher Save 10.7759/cureus.67382

Topics

No keywords indexed for this article. Browse by subject →

References

22

[1]

Tan CH, Onsiong MK. Pain on injection of propofol. Anaesthesia. 1998, 53:468-76. 10.1046/j.1365-2044.1998.00405.x 10.1046/j.1365-2044.1998.00405.x

[2]

Wong WH, Cheong KF. Role of tramadol in reducing pain on propofol injection. Singapore Med J. 2001, 42:193-5.

[3]

Morton NS, Johnston G, White M, Marsh BJ. Propofol in paediatric anaesthesia. Pediatric Anesthesia. 1992, 2:89-97. 10.1111/j.1460-9592.1992.tb00182.x 10.1111/j.1460-9592.1992.tb00182.x

[4]

Desousa KA. Pain on propofol injection: causes and remedies. Indian J Pharmacol. 2016, 48:617-23. 10.4103/0253-7613.194845 10.4103/0253-7613.194845

[5]

El-Radaideh KM. Effect of pretreatment with lidocaine, intravenous paracetamol and lidocaine-fentanyl on propofol injection pain. Comparative study [Article in English, Portuguese]. Rev Bras Anestesiol. 2007, 57:32-8. 10.1590/s0034-70942007000100004 10.1590/s0034-70942007000100004

[6]

Mitchell C, Cheuk SJ, O'Donnell CM, Bampoe S, Walker D. What is the impact of dexamethasone on postoperative pain in adults undergoing general anaesthesia for elective abdominal surgery: a systematic review and meta-analysis. Perioper Med (Lond). 2022, 11:13. 10.1186/s13741-022-00243-6 10.1186/s13741-022-00243-6

[7]

Ye JH, Mui WC, Ren J, Hunt TE, Wu WH, Zbuzek VK. Ondansetron exhibits the properties of a local anesthetic. Anesth Analg. 1997, 1:1116-21. 10.1097/00000539-199711000-00029 10.1097/00000539-199711000-00029

[8]

Tyers MB, Freeman AJ. Mechanism of the anti-emetic activity of 5-HT3 receptor antagonists. Oncology. 1992, 49:263-8. 10.1159/000227054 10.1159/000227054

[9]

A comparative study of attenuation of propofol-induced pain by lignocaine, ondansetron, and ramosetron

RavichandraRamesh Dodawad, GangurBasappa Sumalatha, Sandeep Pandarpurkar et al.

Indian Journal of Anaesthesia 2016 10.4103/0019-5049.174810

[10]

Ahmad S, De Oliveira GS Jr, Fitzgerald PC, McCarthy RJ. The effect of intravenous dexamethasone and lidocaine on propofol-induced vascular pain: a randomized double-blinded placebo-controlled trial. Pain Res Treat. 2013, 2013:734531. 10.1155/2013/734531 10.1155/2013/734531

[11]

Ho CM, Wu HL, Ho ST, Wang JJ. Dexamethasone prevents postoperative nausea and vomiting: benefit versus risk. Acta Anaesthesiol Taiwan. 2011, 49:100-4. 10.1016/j.aat.2011.06.002 10.1016/j.aat.2011.06.002

[12]

Kharitonov SA, Yates DH, Barnes PJ. Inhaled glucocorticoids decrease nitric oxide in exhaled air of asthmatic patients. Am J Respir Crit Care Med. 1996, 153:454-7. 10.1164/ajrccm.153.1.8542158 10.1164/ajrccm.153.1.8542158

[13]

Grabowski PS, Macpherson H, Ralston SH. Nitric oxide production in cells derived from the human joint. Br J Rheumatol. 1996, 35:207-12. 10.1093/rheumatology/35.3.207 10.1093/rheumatology/35.3.207

[14]

Wasinwong W, Termthong S, Plansangkate P, Tanasansuttiporn J, Kosem R, Chaofan S. A comparison of ondansetron and lidocaine in reducing injection pain of propofol: a randomized controlled study. BMC Anesthesiol. 2022, 22:109. 10.1186/s12871-022-01650-4 10.1186/s12871-022-01650-4

[15]

Zahedi H, Nikooseresht M, Seifrabie M. Prevention of propofol injection pain with small-dose ketamine. Middle East J Anaesthesiol. 2009, 20:401-4.

[16]

Adinehmehr L, Salimi S, Sane S, Sina V, Najafizadeh R. Comparison the effect of granisetron and dexamethasone on intravenous propofol pain. Adv Biomed Res. 2018, 7:74. 10.4103/abr.abr_186_17 10.4103/abr.abr_186_17

[17]

Sharma SK, Singh S, Paul D, Ameta N, Taank P, Singh T. Effect of dexamethasone with granisetron or ondansetron for prevention of post-operative nausea vomiting in patients undergoing laparoscopic gynaecological surgery. Int J Res Med Sci. 2020, 8:1331-5. 10.18203/2320-6012.ijrms20201319 10.18203/2320-6012.ijrms20201319

[18]

Sharma M, Gupta S, Purohit S, Goyal AK. The effect of intravenous dexamethasone on intraoperative and early postoperative pain in lumbar spine surgery: a randomized double-blind placebo-controlled study. Anesth Essays Res. 2018, 12:803-8. 10.4103/aer.AER_115_18 10.4103/aer.aer_115_18

[19]

Fonseca NM, Pedrosa LR, Melo N, Oliveira RÁ. Effect of palonosetron, ondansetron and dexamethasone in the prevention of postoperative nausea and vomiting in video cholecystectomy with total venous anesthesia with propofol-remifentanil - randomized clinical trial [Article in Portuguese]. Braz J Anesthesiol. 2020, 70:464-70. 10.1016/j.bjan.2020.08.001 10.1016/j.bjan.2020.08.001

[20]

Saliminia A, Azimaraghi O, Javadi A, Abdoulahpoor M, Movafegh A. Comparison of granisetron and lidocaine on reducing injection pain of etomidate: a controlled randomized study. Rev Bras Anestesiol. 2017, 67:615-8. 10.1016/j.bjane.2017.04.001 10.1016/j.bjane.2017.04.001

[21]

Arslan M, Ciçek R, Kalender HÜ, Yilmaz H. Preventing postoperative nausea and vomiting after laparoscopic cholecystectomy: a prospective, randomized, double-blind study. Curr Ther Res Clin Exp. 2011, 72:1-12. 10.1016/j.curtheres.2011.02.002 10.1016/j.curtheres.2011.02.002

[22]

Wang JJ, Ho ST, Liu YH, Lee SC, Liu YC, Liao YC, Ho CM. Dexamethasone reduces nausea and vomiting after laparoscopic cholecystectomy. Br J Anaesth. 1999, 83:772-5. 10.1093/bja/83.5.772 10.1093/bja/83.5.772

Metrics

0

Citations

22

References

Details

Published: Aug 21, 2024

Authors

Assistant Professor, Department of Anaesthesia, All India Institute of Medical Sciences, Rajkot, Gujarat, India

Associate Professor, Department of Anaesthesia, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India

Department of Anaesthesiology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India

Cite This Article

Aravind Aditya, Khushboo Pandey, Manisha Bhagat, et al. (2024). Comparison of Intravenous Ondansetron and Dexamethasone for Preventing Propofol-Induced Pain During Laparoscopic Cholecystectomy: A Double-Blind, Randomized Study. Cureus. https://doi.org/10.7759/cureus.67382

Comparison of Intravenous Ondansetron and Dexamethasone for Preventing Propofol-Induced Pain During Laparoscopic Cholecystectomy: A Double-Blind, Randomized Study

You May Also Like