journal article Sep 23, 2025

Craniovertebral Junction Compression in Patients With Morquio Syndrome: Case Series and Literature Review

View at Publisher Save 10.7759/cureus.93079
Topics

No keywords indexed for this article. Browse by subject →

References
14
[1]
International Morquio A Registry: Clinical manifestation and natural course of Morquio A disease

A. M. Montaño, S. Tomatsu, G. S. Gottesman et al.

Journal of Inherited Metabolic Disease 2007 10.1007/s10545-007-0529-7
[2]
Michaud M, Belmatoug N, Catros F, Ancellin S, Touati G, Levade T, Gaches F. [Mucopolysaccharidosis: A review]. Rev Med Interne. 2020, 41:180-188. 10.1016/j.revmed.2019.11.010 10.1016/j.revmed.2019.11.010
[3]
White KK, Steinman S, Mubarak SJ. Cervical stenosis and spastic quadriparesis in Morquio disease (MPS IV). A case report with twenty-six-year follow-up. J Bone Joint Surg Am. 2009, 91:438-442. 10.2106/JBJS.H.00148 10.2106/jbjs.h.00148
[4]
Liu HT, Song J, Zhou FC, Liang ZH, Zhang QQ, Zhang YH, Shao J. Cervical spine involvement in pediatric mucopolysaccharidosis patients: clinical features, early diagnosis, and surgical management. Front Surg. 2022, 9:1059567. 10.3389/fsurg.2022.1059567 10.3389/fsurg.2022.1059567
[5]
Stevens JM, Kendall BE, Crockard HA, Ransford A. The odontoid process in Morquio-Brailsford's disease. The effects of occipitocervical fusion. J Bone Joint Surg Br. 1991, 73:851-858. 10.1302/0301-620X.73B5.1910048 10.1302/0301-620x.73b5.1910048
[6]
Cadena Arteaga JA, Lasso Andrade FA, Achicanoy Puchana DM, et al.. Mucopolysaccharidosis type IV: report of 5 cases of Morquio syndrome. Radiol Case Rep. 2021, 17:385-391. 10.1016/j.radcr.2021.11.012 10.1016/j.radcr.2021.11.012
[7]
Demartini Z Jr, Munhoz da Rocha Guimaraes R, Cardoso-Demartini AA. Cervical disorders in mucopolysaccharidosis IVA-Morquio disease. World Neurosurg. 2021, 153:41-43. 10.1016/j.wneu.2021.07.009 10.1016/j.wneu.2021.07.009
[8]
Shukla D, Arvind S, Devi BI. Myelopathy in a dwarf: a case of Morquio's syndrome without odontoid hypoplasia. Neurol India. 2011, 59:126-127. 10.4103/0028-3886.76861 10.4103/0028-3886.76861
[9]
Palmucci S, Attinà G, Lanza ML, et al.. Imaging findings of mucopolysaccharidoses: a pictorial review. Insights Imaging. 2013, 4:443-459. 10.1007/s13244-013-0246-8 10.1007/s13244-013-0246-8
[10]
Giussani C, Guida L, Canonico F, Sganzerla EP. Cerebral and occipito-atlanto-axial involvement in mucopolysaccharidosis patients: clinical, radiological, and neurosurgical features. Ital J Pediatr. 2018, 44:119. 10.1186/s13052-018-0558-x 10.1186/s13052-018-0558-x
[11]
Hughes DG, Chadderton RD, Cowie RA, Wraith JE, Jenkins JP. MRI of the brain and craniocervical junction in Morquio's disease. Neuroradiology. 1997, 39:381-385. 10.1007/s002340050429 10.1007/s002340050429
[12]
Nicolas-Jilwan M. Imaging features of mucopolysaccharidoses in the head and neck. Int J Pediatr Otorhinolaryngol. 2020, 134:110022. 10.1016/j.ijporl.2020.110022 10.1016/j.ijporl.2020.110022
[13]
Muthukumar N. Problems in instrumentation of syndromic craniovertebral junction anomalies - case reports. Neurospine. 2019, 16:277-285. 10.14245/ns.1938176.088 10.14245/ns.1938176.088
[14]
Lyseng-Williamson KA. Elosulfase Alfa: a review of its use in patients with mucopolysaccharidosis type IVA (Morquio A syndrome). BioDrugs. 2014, 28:465-475. 10.1007/s40259-014-0108-z 10.1007/s40259-014-0108-z
Metrics
0
Citations
14
References
Details
Published
Sep 23, 2025
Cite This Article
Purbaday Rakshit, Andi Sadayandi Ramesh, Rajasekar Gopikrishnan, et al. (2025). Craniovertebral Junction Compression in Patients With Morquio Syndrome: Case Series and Literature Review. Cureus. https://doi.org/10.7759/cureus.93079
Related

You May Also Like

Artificial Hallucinations in ChatGPT: Implications in Scientific Writing

Hussam Alkaissi, Samy I McFarlane · 2023

803 citations

Role of Physical Activity on Mental Health and Well-Being: A Review

Aditya Mahindru, Pradeep Patil · 2023

311 citations

Epidemiology of Glaucoma: The Past, Present, and Predictions for the Future

Karen Allison, Deepkumar Patel · 2020

256 citations

Obesity: A Chronic Low-Grade Inflammation and Its Markers

Deepesh Khanna, Siya Khanna · 2022

195 citations