Economic Burden and Clinical Epidemiology of Dialysis: A Cross-Sectional Analysis of Chronic Kidney Disease Patients

Moiz N Butt; Usman Zafar; Farrukh Ansar; Sundas Butt; Abdul Basit; Muhammad Abrar; Syed A Abrar; Ahmed Faraz; Sammar Ahmed; Sultan Awan

doi:10.7759/cureus.93372

journal article Sep 27, 2025

Economic Burden and Clinical Epidemiology of Dialysis: A Cross-Sectional Analysis of Chronic Kidney Disease Patients

Moiz N Butt Usman Zafar

Farrukh Ansar

Sundas Butt Abdul Basit

Muhammad Abrar Syed A Abrar Ahmed Faraz Sammar Ahmed Sultan Awan

Cureus · Springer Science and Business Media LLC

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References

28

[1]

Guo J, Jiao W, Xia S, Xiang X, Zhang Y, Ge X, Sun Q. The global, regional, and national patterns of change in the burden of chronic kidney disease from 1990 to 2021. BMC Nephrol. 2025, 26:136. 10.1186/s12882-025-04028-z 10.1186/s12882-025-04028-z

[2]

Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

Boris Bikbov, Caroline A Purcell, Andrew S Levey et al.

The Lancet 2020 10.1016/s0140-6736(20)30045-3

[3]

Francis A, Harhay MN, Ong AC, et al.. Chronic kidney disease and the global public health agenda: an international consensus. Nat Rev Nephrol. 2024, 20:473-85. 10.1038/s41581-024-00820-6 10.1038/s41581-024-00820-6

[4]

Elshahat S, Cockwell P, Maxwell AP, Griffin M, O'Brien T, O'Neill C. The impact of chronic kidney disease on developed countries from a health economics perspective: a systematic scoping review. PLoS One. 2020, 15:e0230512. 10.1371/journal.pone.0230512 10.1371/journal.pone.0230512

[5]

Darlington O, Dickerson C, Evans M, et al.. Costs and healthcare resource use associated with risk of cardiovascular morbidity in patients with chronic kidney disease: evidence from a systematic literature review. Adv Ther. 2021, 38:994-1010. 10.1007/s12325-020-01607-4 10.1007/s12325-020-01607-4

[6]

Jha V, Al-Ghamdi SM, Li G, et al.. Global economic burden associated with chronic kidney disease: a pragmatic review of medical costs for the inside CKD research programme. Adv Ther. 2023, 40:4405-20. 10.1007/s12325-023-02608-9 10.1007/s12325-023-02608-9

[7]

Nisar M, Tasleem Z, Muhammad SA, et al.. The direct cost of chronic kidney disease (CKD) reported in Asian countries; a systematic literature review. Cost Eff Resour Alloc. 2024, 22:65. 10.1186/s12962-024-00566-9 10.1186/s12962-024-00566-9

[8]

AlRashed H, Miele J, Prasad J, et al.. Systematic review of end stage renal disease in Pakistan: identifying implementation research outcomes. PLoS One. 2023, 18:e0296243. 10.1371/journal.pone.0296243 10.1371/journal.pone.0296243

[9]

Saeed ZI, Hussain SA. Chronic kidney disease in Pakistan: an under-recognized public health problem. Kidney Int. 2012, 81:1151; author reply 1151-2. 10.1038/ki.2012.47 10.1038/ki.2012.47

[10]

Khan SJ, Asif M, Aslam S, Khan WJ, Hamza SA. Pakistan’s healthcare system: a review of major challenges and the first comprehensive universal health coverage initiative. Cureus. 2023, 15:e44641. 10.7759/cureus.44641 10.7759/cureus.44641

[11]

Hasan SS, Mustafa ZU, Kow CS, Merchant HA. "Sehat Sahulat Program": a leap into the universal health coverage in Pakistan. Int J Environ Res Public Health. 2022, 19:10.3390/ijerph19126998 10.3390/ijerph19126998

[12]

Hirsch D, Lau B, Kushwaha V, Yong K. The controversies of coronary artery disease in end-stage kidney disease patients: a narrative review. Rev Cardiovasc Med. 2023, 24:181. 10.31083/j.rcm2406181 10.31083/j.rcm2406181

[13]

Evans M, Bower H, Cockburn E, Jacobson SH, Barany P, Carrero JJ. Contemporary management of anaemia, erythropoietin resistance and cardiovascular risk in patients with advanced chronic kidney disease: a nationwide analysis. Clin Kidney J. 2020, 13:821-7. 10.1093/ckj/sfaa054 10.1093/ckj/sfaa054

[14]

Torres VE, Ahn C, Barten TR, et al.. KDIGO 2025 clinical practice guideline for the evaluation, management, and treatment of autosomal dominant polycystic kidney disease (ADPKD): executive summary. Kidney Int. 2025, 107:234-54. 10.1016/j.kint.2024.07.010 10.1016/j.kint.2024.07.010

[15]

Kalantar-Zadeh K, Casino FG. Let us give twice-weekly hemodialysis a chance: revisiting the taboo. Nephrol Dial Transplant. 2014, 29:1618-20. 10.1093/ndt/gfu096 10.1093/ndt/gfu096

[16]

Soi V, Faber MD, Paul R. Incremental hemodialysis: what we know so far. Int J Nephrol Renovasc Dis. 2022, 15:161-72. 10.2147/IJNRD.S286947 10.2147/ijnrd.s286947

[17]

Mathew AT, Obi Y, Rhee CM, Chou JA, Kalantar-Zadeh K. Incremental dialysis for preserving residual kidney function-does one size fit all when initiating dialysis?. Semin Dial. 2018, 31:343-52. 10.1111/sdi.12701 10.1111/sdi.12701

[18]

Ngeugoue FT, Njoumemi Z, Kaze FF. Monthly direct and indirect costs of management of CKD 3 - 5 non-dialysis patients in an out-of-pocket expenditure system: the case of Yaoundé. Clin Nephrol. 2020, 93:100-2. 10.5414/CNP92S117 10.5414/cnp92s117

[19]

Arodiwe EB, Arodiwe IO, Okoronkwo I. Direct and indirect cost of treatment for chronic kidney disease among patients at the renal unit of the University of Nigeria Teaching Hospital, Enugu. Ethiop J Health Sci. 2024, 34:536-42. 10.4314/ejhs.v34i6.14 10.4314/ejhs.v34i6.14

[20]

Divyaveer SS, Ramachandran R, Sahay M, et al.. International Society of Nephrology Global Kidney Health Atlas: structures, organization, and services for the management of kidney failure in South Asia. Kidney Int Suppl (2011). 2021, 11:e97-e105. 10.1016/j.kisu.2021.01.006 10.1016/j.kisu.2021.01.006

[21]

Malik S, Allen RJ, Vachharajani TJ, Kluger B, Ahmad I, Saeed F. Dialysis decision making, dialysis experiences, and illness perceptions: a qualitative study of Pakistani patients receiving maintenance hemodialysis. Kidney Med. 2022, 4:100550. 10.1016/j.xkme.2022.100550 10.1016/j.xkme.2022.100550

[22]

Bashir S, Kishwar S, Nasir M, Ali S. Socioeconomic inequalities in out-of-pocket and catastrophic health expenditures in Pakistan. Int J Public Health. 2024, 69:1607313. 10.3389/ijph.2024.1607313 10.3389/ijph.2024.1607313

[23]

Households with out-of-pocket payments greater than 40% of capacity to pay for health care (food, housing and utilities approach - developed by WHO/Europe). (2023). https.//www.who.int/data/gho/indicator-metadata-registry/imr-details/4989.

[24]

Manzoor I, Imran M, Niaz A, Arshad A, Majoka AM, Dawood AB. Evaluation of satisfaction level of Sehat Sahulat Programme among patients and doctors in Lahore and Gujranwala districts, Pakistan. J Pak Med Assoc. 2024, 74:2055-60. 10.47391/JPMA.11294 10.47391/jpma.11294

[25]

Utilisation and barriers of social health protection program among its enrolled population of federally administrative areas, Pakistan

Marium Amir Farooqui, Khizar Nabeel Ali, Sonia Riaz

BMJ Open Quality 2024 10.1136/bmjoq-2023-002375

[26]

Pradhan N, Dobre M. Emerging preventive strategies in chronic kidney disease: recent evidence and gaps in knowledge. Curr Atheroscler Rep. 2023, 25:1047-58. 10.1007/s11883-023-01172-5 10.1007/s11883-023-01172-5

[27]

Lok CE, Huber TS, Lee T, et al.. KDOQI clinical practice guideline for vascular access: 2019 update. Am J Kidney Dis. 2020, 75:S1-S164. 10.1053/j.ajkd.2021.02.002 10.1053/j.ajkd.2021.02.002

[28]

Chao K, Sarker MN, Ali I, Firdaus RB, Azman A, Shaed MM. Big data-driven public health policy making: potential for the healthcare industry. Heliyon. 2023, 9:e19681. 10.1016/j.heliyon.2023.e19681 10.1016/j.heliyon.2023.e19681

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Published: Sep 27, 2025

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Cite This Article

Moiz N Butt, Usman Zafar, Farrukh Ansar, et al. (2025). Economic Burden and Clinical Epidemiology of Dialysis: A Cross-Sectional Analysis of Chronic Kidney Disease Patients. Cureus. https://doi.org/10.7759/cureus.93372

Economic Burden and Clinical Epidemiology of Dialysis: A Cross-Sectional Analysis of Chronic Kidney Disease Patients

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