D

Researcher Profile

David E Root

3

Publications

6,413

Citations

10

Co-Authors

3

Active Years

Publications

Journal Article Nature Biotechnology Jan 18, 2016

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

John G Doench · Nicolo Fusi · Meagan Sullender · Mudra Hegde +9 more

10.1038/nbt.3437 4,380 citations

Journal Article Nature Biotechnology Sep 03, 2014

Rational design of highly active sgRNAs for CRISPR-Cas9–mediated gene inactivation

John G Doench · Ella Hartenian · Daniel B Graham · Zuzana Tothova +6 more

10.1038/nbt.3026 1,500 citations

Open Access Journal Article Nature Methods Jun 26, 2011

A public genome-scale lentiviral expression library of human ORFs

Xiaoping Yang · Jesse S Boehm · Xinping Yang · Kourosh Salehi-Ashtiani +20 more

10.1038/nmeth.1638 533 citations

Publication Timeline

2016

1

2014

1

2011

1

Frequent Co-Authors

Meagan Sullender

Ramnik J Xavier

Emma W Vaimberg