L

Researcher Profile

Lesley Tinker

🏛 Division of Public Health Sciences Fred Hutchinson Cancer Research Center Seattle Washington

10

Publications

3,517

Citations

10

Co-Authors

6

Active Years

Publications

Open Access Journal Article Genome Biology Sep 09, 2025

Whole genome sequence analysis of low-density lipoprotein cholesterol across 246 K individuals

Margaret Sunitha Selvaraj · Xihao Li · Zilin Li · Eric Van Buren +440 more

10.1186/s13059-025-03698-0 3 citations

Journal Article Nature Genetics Mar 01, 2022

Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data

Pierrick Wainschtein · Deepti Jain · Zhili Zheng · Stella Aslibekyan +451 more

10.1038/s41588-021-00997-7 304 citations

Open Access Journal Article Nature Communications Oct 11, 2022

Whole genome sequence analysis of blood lipid levels in >66,000 individuals

Margaret Sunitha Selvaraj · Xihao Li · Zilin Li · Akhil Pampana +429 more

10.1038/s41467-022-33510-7 67 citations

Journal Article Nature Methods Oct 27, 2022

A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies

Zilin Li · Xihao Li · Hufeng Zhou · Sheila M. Gaynor +508 more

10.1038/s41592-022-01640-x 104 citations

Open Access Journal Article Nature Feb 10, 2021

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

Daniel Taliun · Daniel N. Harris · Michael D. Kessler · Jedidiah Carlson +419 more

10.1038/s41586-021-03205-y 1,924 citations

Journal Article Nature Genetics Oct 01, 2021

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

Yang Luo · Masahiro Kanai · Wanson Choi · Xinyi Li +428 more

10.1038/s41588-021-00935-7 161 citations

Journal Article Nature Genetics Aug 24, 2020

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

Xihao Li · Zilin Li · Hufeng Zhou · Sheila M. Gaynor +428 more

10.1038/s41588-020-0676-4 256 citations

Journal Article Nature Oct 14, 2020

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

Alexander G. Bick · Joshua S. Weinstock · Satish K. Nandakumar · Charles P. Fulco +408 more

10.1038/s41586-020-2819-2 675 citations

Open Access Journal Article Chest Dec 01, 2019

Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma

Priyadarshini Kachroo · Julian Hecker · Bo L. Chawes · Tarunveer S. Ahluwalia +347 more

10.1016/j.chest.2019.08.2202 6 citations

Open Access Journal Article Cancer Medicine Mar 23, 2018

A prospective study of soluble receptor for advanced glycation end products and adipokines in association with pancreatic cancer in postmenopausal women

Donna L. White · Ron C. Hoogeveen · Liang Chen · Peter Richardson +7 more

10.1002/cam4.1426 17 citations

Publication Timeline

2025

1

2022

3

2021

2

2020

2

2019

1

2018

1

Frequent Co-Authors

Meher Preethi Boorgula

Nora Franceschini

Eric Boerwinkle