Size and Shape of Calcium Alginate Beads Produced by Extrusion Dripping

B.‐B. Lee; P. Ravindra; E.‐S. Chan

doi:10.1002/ceat.201300230

journal article Sep 10, 2013

Size and Shape of Calcium Alginate Beads Produced by Extrusion Dripping

B.‐B. Lee P. Ravindra E.‐S. Chan

Chemical Engineering & Technology Vol. 36 No. 10 pp. 1627-1642 · Wiley

View at Publisher Save 10.1002/ceat.201300230

Abstract

AbstractAlginate hydrogel beads are widely used as an encapsulation medium for biomedical, bioprocessing, and pharmaceutical applications. The size and shape of the beads are often critically controlled since in many usages the beads are monodisperse in size and spherical in shape. Extrusion dripping is a well‐known method to produce alginate beads. Nevertheless, the production of beads of desired size and spherical shape is often achieved based on one's experience or trial and error. An overview is provided on alginate properties, formulation and preparation of alginate and gelling solutions, production conditions, and post‐production treatment that may influence the bead size and shape. Various methods of bead size and shape measurement are also discussed.

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Details

Published: Sep 10, 2013
Vol/Issue: 36(10)
Pages: 1627-1642
License: View

Authors

Cite This Article

B.‐B. Lee, P. Ravindra, E.‐S. Chan (2013). Size and Shape of Calcium Alginate Beads Produced by Extrusion Dripping. Chemical Engineering & Technology, 36(10), 1627-1642. https://doi.org/10.1002/ceat.201300230

Size and Shape of Calcium Alginate Beads Produced by Extrusion Dripping

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