Experimental evaluation of x‐ray acoustic computed tomography for radiotherapy dosimetry applications

Susannah Hickling; Hao Lei; Maritza Hobson; Pierre Léger; Xuanjie Wang; Issam El Naqa

doi:10.1002/mp.12039

journal article Jan 25, 2017

Experimental evaluation of x‐ray acoustic computed tomography for radiotherapy dosimetry applications

Susannah Hickling Hao Lei

Maritza Hobson Pierre Léger Xuanjie Wang

Issam El Naqa

Medical Physics Vol. 44 No. 2 pp. 608-617 · Wiley

View at Publisher Save 10.1002/mp.12039

Abstract

PurposeThe aim of this work was to experimentally demonstrate the feasibility of x‐ray acoustic computed tomography (XACT) as a dosimetry tool in a clinical radiotherapy environment.MethodsThe acoustic waves induced following a single pulse of linear accelerator irradiation in a water tank were detected with an immersion ultrasound transducer. By rotating the collimator and keeping the transducer stationary, acoustic signals at varying angles surrounding the field were detected and reconstructed to form an XACT image. Simulated XACT images were obtained using a previously developed simulation workflow. Profiles extracted from experimental and simulated XACT images were compared to profiles measured with an ion chamber. A variety of radiation field sizes and shapes were investigated.ResultsXACT images resembling the geometry of the delivered radiation field were obtained for fields ranging from simple squares to more complex shapes. When comparing profiles extracted from simulated and experimental XACT images of a 4 cm × 4 cm field, 97% of points were found to pass a 3%/3 mm gamma test. Agreement between simulated and experimental XACT images worsened when comparing fields with fine details. Profiles extracted from experimental XACT images were compared to profiles obtained through clinical ion chamber measurements, confirming that the intensity of XACT images is related to deposited radiation dose. Seventy‐seven percent of the points in a profile extracted from an experimental XACT image of a 4 cm × 4 cm field passed a 7%/4 mm gamma test when compared to an ion chamber measured profile. In a complicated puzzle‐piece shaped field, 86% of the points in an XACT extracted profile passed a 7%/4 mm gamma test.ConclusionsXACT images with intensity related to the spatial distribution of deposited dose in a water tank were formed for a variety of field sizes and shapes. XACT has the potential to be a useful tool for absolute, relative and in vivo dosimetry.

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References

Details

Published: Jan 25, 2017
Vol/Issue: 44(2)
Pages: 608-617
License: View

Authors

S

Susannah Hickling

Department of Physics and Medical Physics Unit McGill University Cedars Cancer Centre Montreal QC Canada H4A 3J1

H

Hao Lei

Department of Mechanical Engineering University of Michigan Ann Arbor MI 48109 USA

M

Maritza Hobson

Medical Physics Unit McGill University Health Centre Cedars Cancer Centre Montreal QC H4A 3J1 Canada

P

Pierre Léger

Medical Physics Unit McGill University Health Centre Cedars Cancer Centre Montreal QC H4A 3J1 Canada

X

Xuanjie Wang

Departments of Radiology and Biomedical Engineering University of Michigan Ann Arbor MI 48109‐0600 USA

I

Issam El Naqa

Department of Radiation Oncology University of Michigan Ann Arbor MI 48103‐4943 USA

Cite This Article

Susannah Hickling, Hao Lei, Maritza Hobson, et al. (2017). Experimental evaluation of x‐ray acoustic computed tomography for radiotherapy dosimetry applications. Medical Physics, 44(2), 608-617. https://doi.org/10.1002/mp.12039

Experimental evaluation of x‐ray acoustic computed tomography for radiotherapy dosimetry applications

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