journal article Jun 01, 2026

A novel antagonist of Vibrio pathogens for aquaculture: Isolation, characterization and probiotic potential of Bacillus safensis ZY-1 from marine sediments

Aquaculture Vol. 620 pp. 743923 · Elsevier BV
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References
93
[1]
Abarike "Traditional Chinese medicine enhances growth, immune response, and resistance to Streptococcus agalactiae in Nile Tilapia" J. Aquat. Anim. Health (2019) 10.1002/aah.10049
[2]
Adams "Progress, challenges and opportunities in fish vaccine development" Fish Shellfish Immunol. (2019) 10.1016/j.fsi.2019.04.066
[3]
Amoah "Paenibacillus polymyxa improves the growth, immune and antioxidant activity, intestinal health, and disease resistance in Litopenaeus vannamei challenged with Vibrio parahaemolyticus" Aquacult (2020) 10.1016/j.aquaculture.2019.734563
[4]
Amoah "In vitro assessment of the safety and potential probiotic characteristics of three Bacillus strains isolated from the intestine of hybrid grouper (Epinephelus fuscoguttatus♀ × Epinephelus lanceolatus♂)" Front. Vet. Sci. (2021) 10.3389/fvets.2021.675962
[5]
Amoah "Identification and characterization of four Bacillus species from the intestine of hybrid grouper (Epinephelus fuscoguttatus♀ × E. lanceolatus♂), their antagonistic role on common pathogenic bacteria, and effects on intestinal health" Fish Shellfish Immunol. (2024) 10.1016/j.fsi.2024.109795
[6]
Andree "Co-infection with Pseudomonas anguilliseptica and Delftia acidovorans in the European eel, Anguilla anguilla (L.): a case history of an illegally trafficked protected species" J. Fish Dis. (2013) 10.1111/jfd.12066
[7]
Arya "Probiotic potential of Bacillus velezensis STPB10 sourced from the gut microbiota of a hillstream fish Schizothorax richardsonii (gray, 1832) for aquaculture applications" Sci. Rep. (2025) 10.1038/s41598-025-02836-9
[8]
Trimmomatic: a flexible trimmer for Illumina sequence data

Anthony M. Bolger, Marc Lohse, Bjoern Usadel

Bioinformatics 2014 10.1093/bioinformatics/btu170
[9]
Borković-Mitić "Integrated biomarker response of oxidative stress parameters in the digestive glands and gills of autochthonous and invasive freshwater mussels from the Sava River, Serbia" Toxics (2024) 10.3390/toxics12100756
[10]
Bruni "Dietary inclusion of full-fat Hermetia illucens prepupae meal in practical diets for rainbow trout (Oncorhynchus mykiss): lipid metabolism and fillet quality investigations" Aquacult (2020) 10.1016/j.aquaculture.2020.735678
[11]
Butprom "Effect of Lactobacillus plantarum C014 on innate immune response and disease resistance against Aeromonas hydrophila in hybrid catfish" Sci. World J. (2013) 10.1155/2013/392523
[12]
Campedelli "Genus-wide assessment of antibiotic resistance in Lactobacillus spp" Appl. Environ. Microbiol. (2019) 10.1128/aem.01738-18
[13]
Chen "Sexual dimorphism in physiological responses of turbot (Scophthalmus maximus L) under acute hypoxia and reoxygenation" Aquacult (2025) 10.1016/j.aquaculture.2024.741614
[14]
Bacillus probiotics

Simon M. Cutting

Food Microbiology 2011 10.1016/j.fm.2010.03.007
[15]
Dai "Simultaneous denitrification and phosphorus removal: a review on the functional strains and activated sludge processes" Sci. Total Environ. (2022) 10.1016/j.scitotenv.2022.155409
[16]
Das "Effects of potential probiotic Bacillus amyloliquifaciens FPTB16 on systemic and cutaneous mucosal immune responses and disease resistance of catla (Catla catla)" Fish Shellfish Immunol. (2013) 10.1016/j.fsi.2013.08.022
[17]
Probiotic application for sustainable aquaculture

Mahmoud A.O. Dawood, Shunsuke Koshio, Mohamed M. Abdel‐Daim et al.

Reviews in Aquaculture 2019 10.1111/raq.12272
[18]
Elshaghabee "Bacillus as potential probiotics: status, concerns, and future perspectives" Front. Microbiol. (2017) 10.3389/fmicb.2017.01490
[19]
Esteban "Effect of dietary supplementation of probiotics and palm fruits extracts on the antioxidant enzyme gene expression in the mucosae of gilthead seabream (Sparus aurata L.)" Fish Shellfish Immunol. (2014) 10.1016/j.fsi.2014.06.012
[20]
Fiocco "How probiotics face food stress: they get by with a little help" Crit. Rev. Food Sci. Nutr. (2020) 10.1080/10408398.2019.1580673
[21]
Fooks "Probiotics as modulators of the gut flora" Br. J. Nutr. (2002) 10.1079/bjn2002628
[22]
Gao "Characterization and mechanism of anti-Aeromonas salmonicida activity of a marine probiotic strain, Bacillus velezensis V4" Appl. Microbiol. Biotechnol. (2017) 10.1007/s00253-017-8095-x
[23]
Gao "The effects of Bacillus subtilis on the immunity, mucosal tissue morphology, immune-related gene transcriptions, and intestinal microbiota in flounder (Paralichthys olivaceus) with two feeding methods: continuous versus discontinuous feeding" Vet. Immunol. Immunopathol. (2024) 10.1016/j.vetimm.2024.110742
[24]
Geng "Effects of environmental pollutant benzop[α]yrene on the innate immunity of Scylla paramamosain and its mechanism" Fish Shellfish Immunol. (2023) 10.1016/j.fsi.2023.109228
[25]
Gerritsen "Intestinal microbiota in human health and disease: the impact of probiotics" Genes Nutr. (2011) 10.1007/s12263-011-0229-7
[26]
Giatsis "Probiotic legacy effects on gut microbial assembly in tilapia larvae" Sci. Rep. (2016) 10.1038/srep33965
[27]
Gong "A new isolate of Pediococcus pentosaceus (SL001) with antibacterial activity against fish pathogens and potency in facilitating the immunity and growth performance of grass carps" Front. Microbiol. (2019) 10.3389/fmicb.2019.01384
[28]
Guglielmotti "Probiotic potential of Lactobacillus delbrueckii strains and their phage resistant mutants" Int. Dairy J. (2007) 10.1016/j.idairyj.2006.11.004
[29]
Guo "Identification and characterization of Bacillus subtilis from grass carp (Ctenopharynodon idellus) for use as probiotic additives in aquatic feed" Fish Shellfish Immunol. (2016) 10.1016/j.fsi.2016.03.017
[30]
He "H2O2-induced oxidative stress responses in Eriocheir sinensis: antioxidant defense and immune gene expression dynamics" Antioxidants (2024) 10.3390/antiox13050524
[31]
Hong "The use of bacterial spore formers as probiotics: table 1" FEMS Microbiol. Rev. (2005) 10.1016/j.femsre.2004.12.001
[32]
Hong "Defining the natural habitat of Bacillus spore-formers" Res. Microbiol. (2009) 10.1016/j.resmic.2009.06.006
[33]
Hu "Use of fermented tea residues as a feed additive and effects on growth performance, body composition, intestinal enzyme activities, and inflammatory biomarkers in juvenile largemouth bass (Micropterus salmoides)" Aquacult. Rep. (2023)
[34]
Janicka "Content and speciation of phosphorus in Lake Kórnickie" Water (2022) 10.3390/w14203234
[35]
Ji "Prebiotics empower probiotics with gastrointestinal stress resistance for colon-targeted release to synergistically alleviate colitis" J. Control. Release (2025) 10.1016/j.jconrel.2025.01.059
[36]
Jia "Physiological response of juvenile turbot (Scophthalmus maximus. L) during hyperthermal stress" Aquaculture (2020) 10.1016/j.aquaculture.2020.735645
[37]
Jiao "Transcriptome analysis reveals the mechanism of the effect of perfluorocaproic acid exposure on brain injury in Carassius auratus" Aquat. Toxicol. (2023) 10.1016/j.aquatox.2023.106709
[38]
Kamilari "Bacillus safensis APC 4099 has broad-spectrum antimicrobial activity against both bacteria and fungi and produces several antimicrobial peptides, including the novel circular bacteriocin safencin E" Appl. Environ. Microbiol. (2025) 10.1128/aem.01942-24
[39]
Kandati "Probiotic Bacillus subtilis attenuates cisplatin-induced multi-organ toxicity via redox modulation and anti-apoptotic mechanisms: evidence from a preclinical probiotic intervention study" Medicine in Microecology (2026) 10.1016/j.medmic.2025.100160
[40]
Koboziev "Role of the enteric microbiota in intestinal homeostasis and inflammation" Free Radic. Biol. Med. (2014) 10.1016/j.freeradbiomed.2013.11.008
[41]
Kuebutornye "In vitro assessment of the probiotic characteristics of three Bacillus species from the gut of Nile Tilapia, Oreochromis niloticus" Probiot. Antimicrob. Proteins (2020) 10.1007/s12602-019-09562-5
[42]
Kumar "Application of probiotics in shrimp aquaculture: importance, mechanisms of action, and methods of administration" Rev. Fish. Sci. Aquac. (2016) 10.1080/23308249.2016.1193841
[43]
Lakshmi "Probiotics as antiviral agents in shrimp aquaculture" J. Pathogens (2013) 10.1155/2013/424123
[44]
Lalloo "High-density spore production of a B. Cereus aquaculture biological agent by nutrient supplementation" Appl. Microbiol. Biotechnol. (2009) 10.1007/s00253-008-1845-z
[45]
Layadi "Effect of Juniperus communis extract on probiotic properties of Bacillus safensis isolated from camel milk in the region of El Oued (Algeria)" Food Sci. Nutr. (2024) 10.1002/fsn3.4262
[46]
Lee "Lactic acid Bacteria-fermented diet containing bacterial extracellular vesicles inhibited pathogenic Bacteria in striped Beakfish (Oplegnathus fasciatus)" Fermentation (2024) 10.3390/fermentation10010049
[47]
Lee "Antimicrobial and immunoprotective effects of Bacillus safensis BS22LVI against acute hepatopancreatic necrosis disease in whiteleg shrimp (Penaeus vannamei)" Aquacult (2026) 10.1016/j.aquaculture.2025.743327
[48]
Li "Advances in the treatment of phosphorus-containing wastewater" IOP Conf. Ser. Earth Environ. Sci. (2021) 10.1088/1755-1315/647/1/012163
[49]
Li "Biological effects of viable and nonviable Bacillus subtilis on the microbiota-gut-blood system through the modulation of gut microbiota and circulating metabolites" J. Future Foods (2025)
[50]
Lin "Multiple probiotic effects of Ligilactobacillus murinus strain S27 on large yellow croaker (Larimichthys crocea): promoting growth, improving intestinal health, and enhancing resistance against Pseudomonas plecoglossicida" Aquacult (2025) 10.1016/j.aquaculture.2025.742657

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Published
Jun 01, 2026
Vol/Issue
620
Pages
743923
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Funding
National Natural Science Foundation of China Award: 32373160
Fundamental Research Funds for the Central Universities Award: 202212012
National Key Research and Development Program of China Award: 2024YFD2401202
Ocean University of China Award: 2022010042
Ministry of Science and Technology of the People's Republic of China
Cite This Article
Ziyue Yang, Xiaolei Wang, Xiaoqian Tang, et al. (2026). A novel antagonist of Vibrio pathogens for aquaculture: Isolation, characterization and probiotic potential of Bacillus safensis ZY-1 from marine sediments. Aquaculture, 620, 743923. https://doi.org/10.1016/j.aquaculture.2026.743923