Cyclin A-cdk1-Dependent Phosphorylation of Bora Is the Triggering Factor Promoting Mitotic Entry

Suzanne Vigneron; Lena Sundermann; Jean-Claude Labbé; Lionel Pintard; Ovidiu Radulescu; Anna Castro; Thierry Lorca

doi:10.1016/j.devcel.2018.05.005

journal article Open Access Jun 01, 2018

Cyclin A-cdk1-Dependent Phosphorylation of Bora Is the Triggering Factor Promoting Mitotic Entry

Suzanne Vigneron Lena Sundermann Jean-Claude Labbé Lionel Pintard

Ovidiu Radulescu

Anna Castro Thierry Lorca

Developmental Cell Vol. 45 No. 5 pp. 637-650.e7 · Elsevier BV

View at Publisher Save 10.1016/j.devcel.2018.05.005

Topics

No keywords indexed for this article. Browse by subject →

References

41

[1]

Abrieu "Mitogen-activated protein kinase activation down-regulates a mechanism that inactivates cyclin B-cdc2 kinase in G2-arrested oocytes" Mol. Biol. Cell (1997) 10.1091/mbc.8.2.249

[2]

Blake-Hodek "Determinants for activation of the atypical AGC kinase Greatwall during M phase entry" Mol. Cell. Biol. (2012) 10.1128/mcb.06525-11

[3]

Burgess "Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance" Proc. Natl. Acad. Sci. USA (2010) 10.1073/pnas.0914191107

[4]

Castro "The anaphase-promoting complex: a key factor in the regulation of cell cycle" Oncogene (2005) 10.1038/sj.onc.1207973

[5]

Chan "Plk1 regulates mitotic Aurora A function through betaTrCP-dependent degradation of hBora" Chromosoma (2008) 10.1007/s00412-008-0165-5

[6]

Clarke "Cyclin A- and cyclin B-dependent protein kinases are regulated by different mechanisms in Xenopus egg extracts" EMBO J. (1992) 10.1002/j.1460-2075.1992.tb05227.x

[7]

Deibler "Quantitative reconstitution of mitotic CDK1 activation in somatic cell extracts" Mol. Cell (2010) 10.1016/j.molcel.2010.02.023

[8]

Dumitru "Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability" eLife (2017) 10.7554/elife.29303

[9]

Eckerdt "Phosphorylation of TPX2 by Plx1 enhances activation of Aurora A" Cell Cycle (2009) 10.4161/cc.8.15.9086

[10]

Eyers "Regulation of Xenopus Aurora A activation by TPX2" J. Biol. Chem. (2004) 10.1074/jbc.m312424200

[11]

Gharbi-Ayachi "The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A" Science (2010) 10.1126/science.1197048

[12]

Gheghiani "PLK1 activation in late G2 sets up commitment to mitosis" Cell Rep. (2017) 10.1016/j.celrep.2017.05.031

[13]

Goldstone "Cdc25-dependent activation of cyclin A/cdk2 is blocked in G2 phase arrested cells independently of ATM/ATR" Oncogene (2001) 10.1038/sj.onc.1204177

[14]

Gu "Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15" EMBO J. (1992) 10.1002/j.1460-2075.1992.tb05493.x

[15]

Hutter "Interlinked bistable mechanisms generate robust mitotic transitions" Cell Cycle (2017) 10.1080/15384101.2017.1371885

[16]

Jang "Phosphorylation of threonine 210 and the role of serine 137 in the regulation of mammalian polo-like kinase" J. Biol. Chem. (2002) 10.1074/jbc.m202172200

[17]

Lane "Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes" J. Cell Biol. (1996) 10.1083/jcb.135.6.1701

[18]

Lindqvist "The decision to enter mitosis: feedback and redundancy in the mitotic entry network" J. Cell Biol. (2009) 10.1083/jcb.200812045

[19]

Lobjois "Study of the docking-dependent PLK1 phosphorylation of the CDC25B phosphatase" Biochem. Biophys. Res. Commun. (2011) 10.1016/j.bbrc.2011.05.110

[20]

Lorca "Constant regulation of both the MPF amplification loop and the Greatwall-PP2A pathway is required for metaphase II arrest and correct entry into the first embryonic cell cycle" J. Cell Sci. (2010) 10.1242/jcs.064527

[21]

Lorca "Fizzy is required for activation of the APC/cyclosome in Xenopus egg extracts" EMBO J. (1998) 10.1093/emboj/17.13.3565

[22]

Macurek "Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery" Nature (2008) 10.1038/nature07185

[23]

Mochida "Regulated activity of PP2A-B55 delta is crucial for controlling entry into and exit from mitosis in Xenopus egg extracts" EMBO J. (2009) 10.1038/emboj.2009.238

[24]

Mochida "Two bistable switches govern M phase entry" Curr. Biol. (2016) 10.1016/j.cub.2016.10.022

[25]

Nakajima "Identification of a consensus motif for Plk (Polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate" J. Biol. Chem. (2003) 10.1074/jbc.c300126200

[26]

Pagano "Cyclin A is required at two points in the human cell cycle" EMBO J. (1992) 10.1002/j.1460-2075.1992.tb05135.x

[27]

Pomerening "Systems-level dissection of the cell-cycle oscillator: bypassing positive feedback produces damped oscillations" Cell (2005) 10.1016/j.cell.2005.06.016

[28]

Qian "Purification and cloning of a protein kinase that phosphorylates and activates the polo-like kinase Plx1" Science (1998) 10.1126/science.282.5394.1701

[29]

Roshak "The human polo-like kinase, PLK, regulates cdc2/cyclin B through phosphorylation and activation of the cdc25C phosphatase" Cell. Signal. (2000) 10.1016/s0898-6568(00)00080-2

[30]

Seki "Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry" Science (2008) 10.1126/science.1157425

[31]

Sha "Hysteresis drives cell-cycle transitions in Xenopus laevis egg extracts" Proc. Natl. Acad. Sci. USA (2003) 10.1073/pnas.0235349100

[32]

Solomon "Cyclin activation of p34cdc2" Cell (1990) 10.1016/0092-8674(90)90504-8

[33]

Tavernier "Cdk1 phosphorylates SPAT-1/Bora to trigger PLK-1 activation and drive mitotic entry in C. elegans embryos" J. Cell Biol. (2015) 10.1083/jcb.201408064

[34]

Thomas "Cdk1 phosphorylates SPAT-1/Bora to promote Plk1 activation in C. elegans and human cells" Cell Rep. (2016) 10.1016/j.celrep.2016.03.049

[35]

Tsai "Changes in oscillatory dynamics in the cell cycle of early Xenopus laevis embryos" PLoS Biol. (2014) 10.1371/journal.pbio.1001788

[36]

Tuck "Robust mitotic entry is ensured by a latching switch" Biol. Open (2013) 10.1242/bio.20135199

[37]

Vigneron "Greatwall maintains mitosis through regulation of PP2A" EMBO J. (2009) 10.1038/emboj.2009.228

[38]

Vigneron "Characterization of the mechanisms controlling Greatwall activity" Mol. Cell. Biol (2011) 10.1128/mcb.00753-10

[39]

Wang "Regulation of polo-like kinase 1 by DNA damage and PP2A/B55alpha" Cell Cycle (2015) 10.4161/15384101.2014.986392

[40]

Watanabe "Cyclin-dependent kinase (CDK) phosphorylation destabilizes somatic Wee1 via multiple pathways" Proc. Natl. Acad. Sci. USA (2005) 10.1073/pnas.0500410102

[41]

Woo "Cyclin-dependent kinases and S phase control in mammalian cells" Cell Cycle (2003) 10.4161/cc.2.4.468

Cited By

111

Proteogenomic Characterization of Endometrial Carcinoma

Yongchao Dou, Emily A. Kawaler · 2020

Cell

Aurora-PLK1 cascades as key signaling modules in the regulation of mitosis

Vladimir Joukov, Arcangela De Nicolo · 2018

Science Signaling

Metrics

111

Citations

41

References

Details

Published: Jun 01, 2018
Vol/Issue: 45(5)
Pages: 637-650.e7
License: View

Authors

Funding

Agence Nationale de la Recherche Award: ANR-17-CE13-0011-01/02

Fondation pour la Recherche Médicale Award: DEQ20150331692

Labex EpiGenMed Award: ANR-10-LABEX-12-01

Cite This Article

Suzanne Vigneron, Lena Sundermann, Jean-Claude Labbé, et al. (2018). Cyclin A-cdk1-Dependent Phosphorylation of Bora Is the Triggering Factor Promoting Mitotic Entry. Developmental Cell, 45(5), 637-650.e7. https://doi.org/10.1016/j.devcel.2018.05.005

Cyclin A-cdk1-Dependent Phosphorylation of Bora Is the Triggering Factor Promoting Mitotic Entry

You May Also Like