Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria

Kohta Ikegami; Stefano Secchia; Omar Almakki; Jason D. Lieb; Ivan P. Moskowitz

doi:10.1016/j.devcel.2020.02.011

journal article Open Access Mar 01, 2020

Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria

Kohta Ikegami

Stefano Secchia

Omar Almakki Jason D. Lieb Ivan P. Moskowitz

Developmental Cell Vol. 52 No. 6 pp. 699-713.e11 · Elsevier BV

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Nuclear lamin phosphorylation: an emerging role in gene regulation and pathogenesis of laminopathies

Sunny Yang Liu, Kohta Ikegami · 2020

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Citations

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References

Details

Published: Mar 01, 2020
Vol/Issue: 52(6)
Pages: 699-713.e11
License: View

Authors

Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.

Lewis Sigler Institute, Princeton University, Princeton, NJ 08544;

I

Ivan P. Moskowitz

Funding

National Institutes of Health

Progeria Research Foundation

Cite This Article

Kohta Ikegami, Stefano Secchia, Omar Almakki, et al. (2020). Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria. Developmental Cell, 52(6), 699-713.e11. https://doi.org/10.1016/j.devcel.2020.02.011

Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria

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