Flavonoids as antioxidants in plants: Location and functional significance

Giovanni Agati; Elisa Azzarello; Susanna Pollastri; Massimiliano Tattini

doi:10.1016/j.plantsci.2012.07.014

journal article Nov 01, 2012

Flavonoids as antioxidants in plants: Location and functional significance

Giovanni Agati Elisa Azzarello Susanna Pollastri

Massimiliano Tattini

Plant Science Vol. 196 pp. 67-76 · Elsevier BV

View at Publisher Save 10.1016/j.plantsci.2012.07.014

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References

122

[1]

Winkel-Shirley "Biosynthesis of flavonoids and effect of stress" Curr. Opin. Plant Biol. (2002) 10.1016/s1369-5266(02)00256-x

[2]

Agati "Multiple functional roles of flavonoids in photoprotection" New Phytol. (2010) 10.1111/j.1469-8137.2010.03269.x

[3]

Pollastri "Flavonols: old compound for old roles" Ann. Bot. (2011) 10.1093/aob/mcr234

[4]

Pourcel "Flavonoid oxidation in plants: from biochemical properties to physiological functions" Trends Plant Sci. (2006) 10.1016/j.tplants.2006.11.006

[5]

Landry "Arabidopsis mutants lacking phenolic sunscreens exhibit enhanced ultraviolet-B injury and oxidative damage" Plant Physiol. (1995) 10.1104/pp.109.4.1159

[6]

Ryan "Flavonoid gene expression and UV photoprotection in transgenic and mutant Petunia leaves" Phytochemistry (2002) 10.1016/s0031-9422(01)00404-6

[7]

Tattini "Differential accumulation of flavonoids and hydroxycinnamates in leaves of Ligustrum vulgare under excess light and drought stress" New Phytol. (2004) 10.1111/j.1469-8137.2004.01126.x

[8]

Tattini "On the role of flavonoids in the integrated mechanisms of response of Ligustrum vulgare and Phillyrea latifolia to high solar radiation" New Phytol. (2005) 10.1111/j.1469-8137.2005.01442.x

[9]

Lillo "Nutrient depletion as a key factor for manipulating gene expression and product formation in different branches of the flavonoid pathway" Plant Cell Environ. (2008) 10.1111/j.1365-3040.2007.01748.x

[10]

Agati "Mesophyll distribution of ‘antioxidant’ flavonoid glycosides in Ligustrum vulgare leaves under contrasting sunlight irradiance" Ann. Bot. (2009) 10.1093/aob/mcp177

[11]

Agati "The biosynthesis of flavonoids is enhanced similarly by UV radiation and root zone salinity in L. vulgare leaves" J. Plant Physiol. (2011) 10.1016/j.jplph.2010.07.016

[12]

Pastori "Common components, networks, and pathways of cross-tolerance to stress. The central role of ‘redox’ and abscisic acid-mediated controls" Plant Physiol. (2002) 10.1104/pp.011021

[13]

Mittler "Reactive oxygen gene network of plants" Trends Plant Sci. (2004) 10.1016/j.tplants.2004.08.009

[14]

Walia "Comparative transcriptional profiling of two contrasting rice genotypes under salinity stress during the vegetative growth stage" Plant Physiol. (2005) 10.1104/pp.105.065961

[15]

Tattini "Morpho-anatomical, physiological and biochemical adjustments in response to root zone salinity stress and high solar radiation in two Mediterranean evergreen shrubs, Myrtus communis and Pistacia lentiscus" New Phytol. (2006) 10.1111/j.1469-8137.2006.01723.x

[16]

Wolf "The molecular and physiological responses of Physcomitrella patens to ultraviolet-B radiation" Plant Physiol. (2010) 10.1104/pp.110.154658

[17]

Taylor "Flavonoids as developmental regulators" Curr. Opin. Plant Biol. (2005) 10.1016/j.pbi.2005.03.005

[18]

Heine "Two cysteines in plant R2R3 MYB domains participate REDOX-dependent DNA binding" J. Biol. Chem. (2004) 10.1074/jbc.m405166200

[19]

Dubos "MYB transcription factors in Arabidopsis" Trends Plant Sci. (2010) 10.1016/j.tplants.2010.06.005

[20]

Falcone Ferreyra "Cloning and characterization of a UV-B-inducible maize flavonol synthase" Plant J. (2010) 10.1111/j.1365-313x.2010.04133.x

[21]

Hatier "Foliar anthocyanins as modulators of stress signals" J. Theor. Biol. (2008) 10.1016/j.jtbi.2008.04.018

[22]

Fini "Drought stress has contrasting effects on antioxidant enzymes activity and phenylpropanoid biosynthesis in Fraxinus ornus leaves: an excess light stress affair?" J. Plant Physiol. (2012) 10.1016/j.jplph.2012.02.014

[23]

Xu "Impact of solar ultraviolet-B on the proteome in soybean lines differing in flavonoid contents" Phytochemistry (2008) 10.1016/j.phytochem.2007.06.010

[24]

Peltzer "Diurnal fluctuations of antioxidative systems in leaves of field-grown beech trees (Fagus sylvatica): responses to light and temperature" Physiol. Plant. (2001) 10.1034/j.1399-3054.2001.1110205.x

[25]

Mullineaux "Signal transduction in response to excess light: getting out of the chloroplast" Curr. Opin. Plant Biol. (2002) 10.1016/s1369-5266(01)00226-6

[26]

Mubarakshina "Production and diffusion of chloroplastic H2O2 and its implication to signalling" J. Exp. Bot. (2010) 10.1093/jxb/erq171

[27]

Close "Rethinking the role of many plant phenolics – protection from photodamage, not herbivores?" Oikos (2002) 10.1034/j.1600-0706.2002.990117.x

[28]

Havaux "The protective functions of carotenoid and flavonoid pigments against excess visible radiation at chilling temperature investigated in Arabidopsis npq and tt mutants" Planta (2001) 10.1007/s004250100572

[29]

Agati "Chloroplast-located flavonoids can scavenge singlet oxygen" New Phytol. (2007) 10.1111/j.1469-8137.2007.01986.x

[30]

McClure "Photocontrol of Spirodella intemedia flavonoids" Plant Physiol. (1968) 10.1104/pp.43.2.193

[31]

Structure-antioxidant activity relationships of flavonoids and phenolic acids

Catherine A. Rice-evans, Nicholas J. Miller, George Paganga

Free Radical Biology and Medicine 1996 10.1016/0891-5849(95)02227-9

[32]

Hernández "How relevant are flavonoids as antioxidants in plants" Trends Plant Sci. (2009) 10.1016/j.tplants.2008.12.003

[33]

Markham "An increase in luteolin: apigenin ratio in Marchantia polymorpha on UV-B enhancement" Phytochemistry (1998) 10.1016/s0031-9422(97)00875-3

[34]

Ryan "UV-B radiation induces increase in quercetin: kaempferol ratio in wild-type and transgenic lines of Petunia" Photochem. Photobiol. (1998)

[35]

Brown "Structural dependence of flavonoid interactions with Cu(II) ions: implication for their antioxidant properties" Biochem. J. (1998) 10.1042/bj3301173

[36]

DeLong "Protein phosphorylation in the delivery of and response to auxin" Plant Mol. Biol. (2002) 10.1023/a:1015246828230

[37]

Peer "Flavonoids as signal molecules" (2006)

[38]

Jansen "Ultraviolet-B-radiation effects on plants: induction of morphogenic responses" Physiol. Plant. (2002) 10.1034/j.1399-3054.2002.1160319.x

[39]

Hectors "The phytohormone auxin is a component of the regulatory system that controls UV-mediated accumulation of flavonoids and UV-induced morphogenesis" Physiol. Plant. (2012) 10.1111/j.1399-3054.2012.01590.x

[40]

Wink "Modes of action of defensive secondary metabolites" (1999)

[41]

Rausher "The evolution of flavonoids and their genes" (2006)

[42]

Stafford "Flavonoid evolution: an enzymic approach" Plant Physiol. (1991) 10.1104/pp.96.3.680

[43]

Cockell "Ultraviolet radiation screening compounds" Biol. Rev. (1999) 10.1017/s0006323199005356

[44]

Rozema "UV-B as an environmental factor in plant life: stress and regulation" Trends Ecol. Evol. (1997) 10.1016/s0169-5347(96)10062-8

[45]

Burchard "Contribution of hydroxycinnamates and flavonoids to epidermal shielding of UV-A and UV-B radiation in developing rye primary leaves as measured by ultraviolet-induced chlorophyll fluorescence measurements" Plant Cell Environ. (2000) 10.1046/j.1365-3040.2000.00633.x

[46]

Tattini "Flavonoids accumulate in leaves and glandular trichomes of Phillyrea latifolia exposed to excess solar radiation" New Phytol. (2000) 10.1046/j.1469-8137.2000.00743.x

[47]

Agati "Flavonoid distribution in tissues of Phillyrea latifolia as estimated by microspectrofluorometry and multispectral fluorescence microimaging" Photochem. Photobiol. (2002) 10.1562/0031-8655(2002)076<0350:fditop>2.0.co;2

[48]

Strack "Cell wall-conjugated phenolics from Coniferae leaves" Phytochemistry (1988) 10.1016/0031-9422(88)80759-3

[49]

Tattini "Morphology and biochemistry of on-glandular trichomes in Cistus salvifolius leaves growing in extreme habitats of the Mediterranean basin" Plant Biol. (2007) 10.1055/s-2006-924662

[50]

Yamasaki "Flavonoid-peroxidase reaction as a detoxification mechanism of plant cells against H2O2" Plant Physiol. (1997) 10.1104/pp.115.4.1405

Showing 50 of 122 references

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Details

Published: Nov 01, 2012
Vol/Issue: 196
Pages: 67-76
License: View

Authors

Institute for Sustainable Plant Protection National Research Council of Italy Via Madonna del Piano 10 Sesto Fiorentino 50019 Florence Italy; Department of Biosciences Durham University South Road DH1 3LE Durham UK

M

Massimiliano Tattini

Cite This Article

Giovanni Agati, Elisa Azzarello, Susanna Pollastri, et al. (2012). Flavonoids as antioxidants in plants: Location and functional significance. Plant Science, 196, 67-76. https://doi.org/10.1016/j.plantsci.2012.07.014

Flavonoids as antioxidants in plants: Location and functional significance

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