On-demand optogenetic control of spontaneous seizures in temporal lobe epilepsy

Esther Krook-Magnuson; Caren Armstrong; Mikko Oijala; Ivan Soltesz

doi:10.1038/ncomms2376

journal article Open Access Jan 22, 2013

On-demand optogenetic control of spontaneous seizures in temporal lobe epilepsy

Esther Krook-Magnuson

Caren Armstrong Mikko Oijala Ivan Soltesz

Nature Communications Vol. 4 No. 1 · Springer Science and Business Media LLC

View at Publisher Save 10.1038/ncomms2376

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References

30

[1]

Chang, B. S. & Lowenstein, D. H. . Epilepsy. N Engl. J. Med. 349, 1257–1266 (2003). 10.1056/nejmra022308

[2]

Gloor, P., Olivier, A., Quesney, L. F., Andermann, F. & Horowitz, S. . The role of the limbic system in experiential phenomena of temporal lobe epilepsy. Ann. Neurol. 12, 129–144 (1982). 10.1002/ana.410120203

[3]

Morrell, M. J. . Responsive cortical stimulation for the treatment of medically intractable partial epilepsy. Neurology 77, 1295–1304 (2011). 10.1212/wnl.0b013e3182302056

[4]

Millisecond-timescale, genetically targeted optical control of neural activity

Edward S Boyden, Feng Zhang, Ernst Bamberg et al.

Nature Neuroscience 2005 10.1038/nn1525

[5]

Gradinaru, V. et al. Targeting and readout strategies for fast optical neural control in vitro and in vivo. J. Neurosci. 27, 14231–14238 (2007). 10.1523/jneurosci.3578-07.2007

[6]

Molecular and Cellular Approaches for Diversifying and Extending Optogenetics

Viviana Gradinaru, Feng Zhang, Charu Ramakrishnan et al.

Cell 2010 10.1016/j.cell.2010.02.037

[7]

Tonnesen, J., Sorensen, A. T., Deisseroth K., Lundberg, C. & Kokaia, M. . Optogenetic control of epileptiform activity. Proc. Natl Acad. Sci. USA 106, 12162–12167 (2009). 10.1073/pnas.0901915106

[8]

Wykes, R. C. et al. Optogenetic and potassium channel gene therapy in a rodent model of focal neocortical epilepsy. Sci. Transl. Med. 4, 161ra152 (2012). 10.1126/scitranslmed.3004190

[9]

Paz, J. T. et al. Closed-loop optogenetic control of thalamus as a tool for interrupting seizures after cortical injury. Nat. Neurosci. 16, 64–70 (2012). 10.1038/nn.3269

[10]

Freund, T. F. & Buzsaki, G. . Interneurons of the hippocampus. Hippocampus 6, 347–470 (1996). 10.1002/(sici)1098-1063(1996)6:4<347::aid-hipo1>3.0.co;2-i

[11]

Woodson, W., Nitecka, L. & Ben-Ari Y. . Organization of the GABAergic system in the rat hippocampal formation: a quantitative immunocytochemical study. J. Comp. Neurol. 280, 254–271 (1989). 10.1002/cne.902800207

[12]

Bragin, A., Engel, J. Jr, Wilson C. L., Vizentin, E. & Mathern, G. W. . Electrophysiologic analysis of a chronic seizure model after unilateral hippocampal KA injection. Epilepsia 40, 1210–1221 (1999). 10.1111/j.1528-1157.1999.tb00849.x

[13]

Cavalheiro, E. A., Riche, D. A. & Le Gal La Salle, G. . Long-term effects of intrahippocampal kainic acid injection in rats: a method for inducing spontaneous recurrent seizures. Electroencephalogr. Clin. Neurophysiol. 53, 581–589 (1982). 10.1016/0013-4694(82)90134-1

[14]

Staba, R. J. et al. Gray matter loss correlates with mesial temporal lobe neuronal hyperexcitability inside the human seizure-onset zone. Epilepsia 53, 25–34 (2012). 10.1111/j.1528-1167.2011.03333.x

[15]

Modification of seizure activity by electrical stimulation: II. Motor seizure

Ronald J Racine

Electroencephalography and Clinical Neurophysiolog... 1972 10.1016/0013-4694(72)90177-0

[16]

Tsien, J. Z. et al. Subregion- and cell type-restricted gene knockout in mouse brain. Cell 87, 1317–1326 (1996). 10.1016/s0092-8674(00)81826-7

[17]

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

Linda Madisen, Tianyi Mao, Henner Koch et al.

Nature Neuroscience 2012 10.1038/nn.3078

[18]

Zhang, F. et al. Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri. Nat. Neurosci. 11, 631–633 (2008). 10.1038/nn.2120

[19]

Hajos, N. & Paulsen, O. . Network mechanisms of gamma oscillations in the CA3 region of the hippocampus. Neural. Netw. 22, 1113–1119 (2009) . 10.1016/j.neunet.2009.07.024

[20]

Cobb, S. R., Buhl, E. H., Halasy K., Paulsen, O. & Somogyi, P. . Synchronization of neuronal activity in hippocampus by individual GABAergic interneurons. Nature 378, 75–78 (1995) . 10.1038/378075a0

[21]

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

Vikaas S. Sohal, Feng Zhang, Ofer Yizhar et al.

Nature 2009 10.1038/nature07991

[22]

Hippenmeyer, S. et al. A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 3, e159 (2005). 10.1371/journal.pbio.0030159

[23]

Wada, J. A. . Callosal bisection and transcallosal secondary antiepileptogenesis. Epilepsia 46, (Suppl 1): 2–6 (2005). 10.1111/j.0013-9580.2005.461002.x

[24]

Aravanis, A. M. et al. An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology. J. Neural. Eng. 4, S143–S156 (2007) . 10.1088/1741-2560/4/3/s02

[25]

Berenyi, A., Belluscio, M., Mao D. & Buzsaki, G. . Closed-loop control of epilepsy by transcranial electrical stimulation. Science 337, 735–737 (2012). 10.1126/science.1223154

[26]

Good, L. B. et al. Control of synchronization of brain dynamics leads to control of epileptic seizures in rodents. Int. J. Neural. Syst. 19, 173–196 (2009). 10.1142/s0129065709001951

[27]

Klausberger, T. & Somogyi, P. . Neuronal diversity and temporal dynamics: the unity of hippocampal circuit operations. Science 321, 53–57 (2008). 10.1126/science.1149381

[28]

Armstrong, C. & Soltesz, I. . Basket cell dichotomy in microcircuit function. J. Physiol. 590, 683–694 (2012). 10.1113/jphysiol.2011.223669

[29]

Howard, A., Tamas, G. & Soltesz I. . Lighting the chandelier: new vistas for axo-axonic cells. Trends Neurosci. 28, 310–316 (2005). 10.1016/j.tins.2005.04.004

[30]

Binding, J. et al. Brain refractive index measured in vivo with high-NA defocus-corrected full-field OCT and consequences for two-photon microscopy. Opt. Express 19, 4833–4847 (2011) . 10.1364/oe.19.004833

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Published: Jan 22, 2013
Vol/Issue: 4(1)
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Authors

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Esther Krook-Magnuson

Neuroscience Department, University of Minnesota, Minneapolis, United States

Cite This Article

Esther Krook-Magnuson, Caren Armstrong, Mikko Oijala, et al. (2013). On-demand optogenetic control of spontaneous seizures in temporal lobe epilepsy. Nature Communications, 4(1). https://doi.org/10.1038/ncomms2376

On-demand optogenetic control of spontaneous seizures in temporal lobe epilepsy

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